Recurrence of Listeria monocytogenes meningitis

A case of Listeria monocytogenes meningitis in a 3-year-old boy which relapsed after chloramphenicol treatment is described. The patient was subsequently successfully treated with ampicillin and gentamicin and made a complete recovery. In vitro studies confirmed the inadequacy of chloramphenicol the...

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Bibliographic Details
Published in:	The Journal of infection Vol. 16; no. 1; p. 65
Main Authors:	Richards, J, Swann, R A, Ponton, A W
Format:	Journal Article
Language:	English
Published:	England 01-01-1988
Subjects:	Ampicillin - therapeutic use Child, Preschool Chloramphenicol - therapeutic use Drug Combinations - therapeutic use Drug Interactions Gentamicins - therapeutic use Humans Listeria monocytogenes - drug effects Male Meningitis, Listeria - diagnosis Meningitis, Listeria - drug therapy Recurrence
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Summary:	A case of Listeria monocytogenes meningitis in a 3-year-old boy which relapsed after chloramphenicol treatment is described. The patient was subsequently successfully treated with ampicillin and gentamicin and made a complete recovery. In vitro studies confirmed the inadequacy of chloramphenicol therapy. The value of combination therapy, as evidenced by chessboard and killing-curve techniques with the strain, is discussed.
ISSN:	0163-4453
DOI:	10.1016/S0163-4453(88)96161-0