Search Results - "Pons, Nicolas"
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Alterations of the human gut microbiome in liver cirrhosis
Published in Nature (London) (04-09-2014)“…Liver cirrhosis occurs as a consequence of many chronic liver diseases that are prevalent worldwide. Here we characterize the gut microbiome in liver cirrhosis…”
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Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake
Published in Gut (01-07-2020)“…This study aimed to explore the effects of an isocaloric Mediterranean diet (MD) intervention on metabolic health, gut microbiome and systemic metabolome in…”
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Major microbiota dysbiosis in severe obesity: fate after bariatric surgery
Published in Gut (01-01-2019)“…Decreased gut microbial gene richness (MGR) and compositional changes are associated with adverse metabolism in overweight or moderate obesity, but lack…”
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Changes of the human gut microbiome induced by a fermented milk product
Published in Scientific reports (11-09-2014)“…The gut microbiota (GM) consists of resident commensals and transient microbes conveyed by the diet but little is known about the role of the latter on GM…”
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Gut Bacteria Composition Drives Primary Resistance to Cancer Immunotherapy in Renal Cell Carcinoma Patients
Published in European urology (01-08-2020)“…The development of immune checkpoint blockade (ICB) has revolutionized the clinical outcome of renal cell carcinoma (RCC). Nevertheless, improvement of…”
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Indole, a Signaling Molecule Produced by the Gut Microbiota, Negatively Impacts Emotional Behaviors in Rats
Published in Frontiers in neuroscience (09-04-2018)“…Gut microbiota produces a wide and diverse array of metabolites that are an integral part of the host metabolome. The emergence of the gut microbiome-brain…”
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A metagenome-wide association study of gut microbiota in type 2 diabetes
Published in Nature (London) (04-10-2012)“…Assessment and characterization of gut microbiota has become a major research area in human disease, including type 2 diabetes, the most prevalent endocrine…”
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Protection of the Human Gut Microbiome From Antibiotics
Published in The Journal of infectious diseases (30-01-2018)“…In a phase 1 clinical study, coadministration of the adsorbent-based DAV132 product together with the fluoroquinolone antibiotic moxifloxacin, while not…”
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CDC20B is required for deuterosome-mediated centriole production in multiciliated cells
Published in Nature communications (07-11-2018)“…Multiciliated cells (MCCs) harbor dozens to hundreds of motile cilia, which generate hydrodynamic forces important in animal physiology. In vertebrates, MCC…”
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Benchmarking second and third-generation sequencing platforms for microbial metagenomics
Published in Scientific data (11-11-2022)“…Shotgun metagenomic sequencing is a common approach for studying the taxonomic diversity and metabolic potential of complex microbial communities. Current…”
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Overview of a surface-ripened cheese community functioning by meta-omics analyses
Published in PloS one (13-04-2015)“…Cheese ripening is a complex biochemical process driven by microbial communities composed of both eukaryotes and prokaryotes. Surface-ripened cheeses are…”
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Identification of rumen microbial biomarkers linked to methane emission in Holstein dairy cows
Published in Journal of animal breeding and genetics (1986) (01-01-2020)“…Mitigation of greenhouse gas emissions is relevant for reducing the environmental impact of ruminant production. In this study, the rumen microbiome from…”
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Dissemination of the mcr-1 colistin resistance gene
Published in The Lancet infectious diseases (01-03-2016)“…[...]we showed that the newly described mcr-1 gene has been disseminating in China since before 2010, as a mobile form…”
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The bacterial species profiles of the lingual and salivary microbiota differ with basic tastes sensitivity in human
Published in Scientific reports (20-11-2023)“…Taste perception is crucial and impairments, which can be linked to pathologies, can lead to eating disorders. It is triggered by taste compounds stimulating…”
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Characterizing isomiR variants within the microRNA‐34/449 family
Published in FEBS letters (01-03-2017)“…miR‐34/449 microRNAs are conserved regulators of multiciliated cell differentiation. Here, we evidence and characterize expression of two isomiR variant…”
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The gut microbiota in multiple sclerosis varies with disease activity
Published in Genome medicine (05-01-2023)“…Multiple sclerosis is a chronic immune-mediated disease of the brain and spinal cord resulting in physical and cognitive impairment in young adults. It is…”
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The "one airway, one disease" concept in light of Th2 inflammation
Published in The European respiratory journal (01-10-2018)“…In line with the pathophysiological continuum described between nose and bronchus in allergic respiratory diseases, we assessed whether nasal epithelium could…”
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Inferring Aggregated Functional Traits from Metagenomic Data Using Constrained Non-negative Matrix Factorization: Application to Fiber Degradation in the Human Gut Microbiota
Published in PLoS computational biology (01-12-2016)“…Whole Genome Shotgun (WGS) metagenomics is increasingly used to study the structure and functions of complex microbial ecosystems, both from the taxonomic and…”
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Diet and gut microbiome interactions of relevance for symptoms in irritable bowel syndrome
Published in Microbiome (26-03-2021)“…While several studies have documented associations between dietary habits and microbiota composition and function in healthy individuals, no study explored…”
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Increasing the diversity of dietary fibers in a daily-consumed bread modifies gut microbiota and metabolic profile in subjects at cardiometabolic risk
Published in Gut microbes (2022)“…Some cardiometabolic risk factors such as dyslipidemia and insulin resistance are known to be associated with low gut microbiota richness. A link between gut…”
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