Search Results - "Ponomaryova, Anastasia"
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Tumor-Associated Macrophages in Human Breast, Colorectal, Lung, Ovarian and Prostate Cancers
Published in Frontiers in oncology (22-10-2020)“…Tumor-associated macrophages (TAMs) are major innate immune cells that constitute up to 50% of the cell mass of human tumors. TAMs are highly heterogeneous…”
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The potential of circulating cell-free RNA as a cancer biomarker: challenges and opportunities
Published in Expert review of molecular diagnostics (01-02-2018)“…Cancer statistics show that recent improvements in cancer management are only mildly effective in the absence of reliable biomarkers for the detection,…”
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Plasma miR-19b and miR-183 as Potential Biomarkers of Lung Cancer
Published in PloS one (21-10-2016)“…Lung cancer is a complex disease that often manifests at the point when treatment is not effective. Introduction of blood-based complementary diagnostics using…”
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Genomic and Transcriptomic Research in the Discovery and Application of Colorectal Cancer Circulating Markers
Published in International journal of molecular sciences (01-08-2023)“…Colorectal cancer (CRC) is the most frequently occurring malignancy in the world. However, the mortality from CRC can be reduced through early diagnostics,…”
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Premalignant lesions of squamous cell carcinoma of the lung: The molecular make-up and factors affecting their progression
Published in Lung cancer (Amsterdam, Netherlands) (01-09-2019)“…•Bronchial premalignant lesions may progress to cancer or regress to normal mucosa.•The progression of bronchial lesions is governed by exo- and endogenous…”
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Aberrant Methylation of LINE-1 Transposable Elements: A Search for Cancer Biomarkers
Published in Cells (Basel, Switzerland) (02-09-2020)“…Cancer remains one of the main causes of human mortality despite significant progress in its diagnostics and therapy achieved in the past decade. Massive…”
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Profiling of 179 miRNA Expression in Blood Plasma of Lung Cancer Patients and Cancer-Free Individuals
Published in Scientific reports (20-04-2018)“…Lung cancer is one of major cancers, and survival of lung cancer patients is dictated by the timely detection and diagnosis. Cell-free circulating miRNAs were…”
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Potentialities of aberrantly methylated circulating DNA for diagnostics and post-treatment follow-up of lung cancer patients
Published in Lung cancer (Amsterdam, Netherlands) (01-09-2013)“…Abstract To date, aberrant DNA methylation has been shown to be one of the most common and early causes of malignant cell transformation and tumors of…”
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Dynamic Changes in Circulating Methylated Markers in Response to Antitumor Therapy of Rectal Cancer
Published in Journal of gastrointestinal cancer (01-09-2024)“…Background Rectal cancer (RC) occupies a leading position in the structure of oncological morbidity and mortality. Aberrant methylation of tumor-suppressor…”
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Long interspersed nuclear element-1 methylation status in the circulating DNA from blood of patients with malignant and chronic inflammatory lung diseases
Published in European journal of cancer prevention (01-03-2021)“…Along with other malignant diseases, lung cancer arises from the precancerous lung tissue state. Aberrant DNA methylation (hypermethylation of certain genes…”
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Hypomethylation of human-specific family of LINE-1 retrotransposons in circulating DNA of lung cancer patients
Published in Lung cancer (Amsterdam, Netherlands) (01-09-2016)“…Highlights • MIRA detects hypomethylation of LINE-1 promoters in csbDNA of lung cancer patients. • Level of hypomethylation is more pronounced for…”
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Cell-free and cell-bound circulating nucleic acid complexes: mechanisms of generation, concentration and content
Published in Expert opinion on biological therapy (01-06-2012)“…Extracellular nucleic acids are found in human blood and cell culture medium as cell-free or being adsorbed at cell surface. In the last years, the circulating…”
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Recurrence of squamous cell lung carcinoma is associated with the co-presence of reactive lesions in tumor-adjacent bronchial epithelium
Published in Tumor biology (01-03-2016)“…Recurrences occur in 30 % of lung cancer patients after radical therapy; however, known prognostic factors are not always effective. In this study, we…”
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Dynamic changes in circulating miRNA levels in response to antitumor therapy of lung cancer
Published in Experimental lung research (07-02-2016)“…Purpose: Expression levels of cancer-associated microRNAs were reported to be altered in serum/plasma samples from lung cancer patients compared with healthy…”
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RARβ2 gene methylation level in the circulating DNA from blood of patients with lung cancer
Published in European journal of cancer prevention (01-11-2011)“…Alterations in the patterns of DNA methylation are among the earliest and most common events in tumorigenesis. Epigenetic changes were shown to be detectable…”
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Circulating DNA-based lung cancer diagnostics and follow-up: looking for epigenetic markers
Published in Translational cancer research (01-03-2018)Get full text
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