Search Results - "Pongratz, I."

The hsp90 Chaperone Complex Regulates Intracellular Localization of the Dioxin Receptor by Kazlauskas, Arunas, Sundström, Sara, Poellinger, Lorenz, Pongratz, Ingemar

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The Immunophilin-like Protein XAP2 Regulates Ubiquitination and Subcellular Localization of the Dioxin Receptor by Kazlauskas, Arunas, Poellinger, Lorenz, Pongratz, Ingemar

“…The dioxin (aryl hydrocarbon) receptor is a ligand-dependent transcription factor that induces expression of a number of genes encoding drug metabolizing…”
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Biotransformation of genistein and bisphenol A in cell lines used for screening endocrine disruptors by Bursztyka, J., Perdu, E., Pettersson, K., Pongratz, I., Fernández-Cabrera, M., Olea, N., Debrauwer, L., Zalko, D., Cravedi, J.P.

“…In vitro assays provide the opportunity for generating alerts for chemicals which interact with hormone receptors and are also valuable tools for mechanistic…”
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Endocrine disruptors targeting ERβ function by Swedenborg, E, Pongratz, I, Gustafsson, J.-Å

“…Endocrine disruptive chemicals (EDCs) circulating in the environment constitute a risk to ecosystems, wildlife and human health. Oestrogen receptor (ER) alpha…”
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Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor by WHITELAW, M, PONGRATZ, I, WILHELMSSON, A, GUSTAFSSON, J.-Å, POELLINGER, L

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Dual roles of the 90-kDa heat shock protein hsp90 in modulating functional activities of the dioxin receptor. Evidence that the dioxin receptor functionally belongs to a subclass of nuclear receptors which require hsp90 both for ligand binding activity and repression of intrinsic DNA binding activity by PONGRATZ, I, MASON, G. G. F, POELLINGER, L

“…Signal transduction by dioxin (2,3,7,8-tetrachloro-dibenzo-p-dioxin) is mediated by the intracellular dioxin receptor which, in its dioxin-activated state,…”
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Cross-coupling of signal transduction pathways: the dioxin receptor mediates induction of cytochrome P-450IA1 expression via a protein kinase C-dependent mechanism by BERGHARD, A, GRADIN, K, PONGRATZ, I, WHITELAW, M, POELLINGER, L

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AhR and ARNT modulate ER signaling by Swedenborg, Elin, Pongratz, Ingemar

“…Abstract The aryl hydrocarbon receptor (AhR), in complex with its binding partner ARNT, mediates the cellular response to xenobiotic compounds such as the…”
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A cellular factor stimulates ligand-dependent release of hsp90 from the basic helix-loop-helix dioxin receptor by MCGUIRE, J, WHITELAW, M. L, PONGRATZ, I, GUSTAFSSON, J.-Å, POELLINGER, L

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Biotransformation of bisphenol A and genistein in MCF7, HC11 and HepG2 cell lines used for testing endocrine disruptors by Bursztyka, J., Perdu, E., Pettersson, K., Pongratz, I., Fernández-Cabrera, M., Olea, N., Gamet-Payrastre, L., Cravedi, J.P., Zalko, D.

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Inhibition of the specific DNA binding activity of the dioxin receptor by phosphatase treatment by PONGRATZ, I, STROMSTEDT, P.-E, MASON, G. G. F, POELLINGER, L

“…The dioxin receptor stimulates transcription of the cytochrome P-450IA1 gene in response to dioxin. Exposure of the intracellular dioxin receptor to dioxin…”
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Endocrine disruptive chemicals: mechanisms of action and involvement in metabolic disorders by Swedenborg, Elin, Rüegg, Joëlle, Mäkelä, Sari, Pongratz, Ingemar

“…Endocrine disruption refers to the ability of chemicals to interfere with hormonal systems, and has raised considerable concern in recent years. Endocrine…”
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Assembly of a glucocorticoid receptor complex prior to DNA binding enhances its specific interaction with a glucocorticoid response element by CAIRNS, W, CAIRNS, C, PONGRATZ, I, POELLINGER, L, OKRET, S

“…Gel retardation analysis with full- and half-palindromic sequences using partially purified glucocorticoid receptor (GR) resulted in GR-glucocorticoid response…”
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Tryptamine Serves As a Proligand of the AhR Transcriptional Pathway Whose Activation Is Dependent of Monoamine Oxidases by Vikström Bergander, Linda, Cai, Wen, Klocke, Bernward, Seifert, Martin, Pongratz, Ingemar

“…The function of the aryl hydrocarbon receptor (AhR) in mediating the biological effect to environmental pollutants is well established. However, accumulated…”
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The Transcription Factor Aryl Hydrocarbon Receptor Nuclear Translocator Functions as an Estrogen Receptor β-Selective Coactivator, and Its Recruitment to Alternative Pathways Mediates Antiestrogenic Effects of Dioxin by Rüegg, Joëlle, Swedenborg, Elin, Wahlström, David, Escande, Aurelie, Balaguer, Patrick, Pettersson, Katarina, Pongratz, Ingemar

“…The biological effects of dioxins are mediated by the aryl hydrocarbon receptor (AhR) and its dimerization partner, the AhR nuclear translocator (ARNT), and…”
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Regulation of estrogen receptor beta activity and implications in health and disease by Swedenborg, Elin, Power, Krista A, Cai, Wen, Pongratz, Ingemar, Rüegg, Joëlle

“…Together with the estrogen receptor (ER) alpha, estrogen receptor beta (ERβ) mediates many of the physiological effects of estrogens. As ERβ is crucially…”
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Epigenetic Regulation of Glucose Transporter 4 by Estrogen Receptor β by Rüegg, Joëlle, Cai, Wen, Karimi, Mohsen, Kiss, Nimrod B, Swedenborg, Elin, Larsson, Catharina, Ekström, Tomas J, Pongratz, Ingemar

“…Glucose transporter 4 (Glut4) is an important regulator of cellular glucose uptake in adipose tissue and skeletal muscle. The estrogen receptors α and β (ERα…”
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Diet-Derived Polyphenol Metabolite Enterolactone Is a Tissue-Specific Estrogen Receptor Activator by Penttinen, Pauliina, Jaehrling, Jan, Damdimopoulos, Anastasios E, Inzunza, José, Lemmen, Josephine G, van der Saag, Paul, Pettersson, Katarina, Gauglitz, Günter, Mäkelä, Sari, Pongratz, Ingemar

“…Numerous dietary compounds can modify gene expression by binding to the members of the nuclear receptor superfamily of transcription factors. For example,…”
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Evidence That the Co-chaperone p23 Regulates Ligand Responsiveness of the Dioxin (Aryl Hydrocarbon) Receptor by Kazlauskas, Arunas, Poellinger, Lorenz, Pongratz, Ingemar

“…The dioxin (aryl hydrocarbon) receptor is a ligand-dependent transcription factor that induces expression of a number of genes encoding drug metabolizing…”
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A single dose of enterolactone activates estrogen signaling and regulates expression of circadian clock genes in mice by Damdimopoulou, Pauliina, Nurmi, Tarja, Salminen, Anu, Damdimopoulos, Anastasios E, Kotka, Maria, van der Saag, Paul, Strauss, Leena, Poutanen, Matti, Pongratz, Ingemar, Mäkelä, Sari

“…Enterolactone (EL) is an enterolignan produced by gut microbiota from dietary plant lignans. Epidemiological and experimental studies suggest that EL and plant…”
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