Search Results - "Pongracic, Jacqueline"
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Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations
Published in Journal of allergy and clinical immunology (01-12-2015)“…Background Short-term targeted treatment can potentially prevent fall asthma exacerbations while limiting therapy exposure. Objective We sought to compare (1)…”
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2
Omalizumab facilitates rapid oral desensitization for peanut allergy
Published in Journal of allergy and clinical immunology (01-03-2017)“…Background Peanut oral immunotherapy is a promising approach to peanut allergy, but reactions are frequent, and some patients cannot be desensitized. The…”
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Multicenter, randomized, double-blind, placebo-controlled clinical trial of vital wheat gluten oral immunotherapy
Published in Journal of allergy and clinical immunology (01-02-2019)“…Wheat is a common food allergen that can cause anaphylaxis. We sought to determine the efficacy and safety of vital wheat gluten (VWG) oral immunotherapy…”
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The prevalence, severity, and distribution of childhood food allergy in the United States
Published in Pediatrics (Evanston) (01-07-2011)“…The goal of this study was to better estimate the prevalence and severity of childhood food allergy in the United States. A randomized, cross-sectional survey…”
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Primary Prevention of Allergic Disease Through Nutritional Interventions
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01-01-2013)“…With the rising prevalence of atopic disease, primary prevention may play a role in reducing its burden, especially in high-risk infants. With this in mind,…”
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Randomized Trial of Omalizumab (Anti-IgE) for Asthma in Inner-City Children
Published in The New England journal of medicine (17-03-2011)“…In this study, the introduction of guidelines-based therapy in all children decreased the number of days per fortnight that children had asthma symptoms…”
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Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion Among Children With Peanut Allergy: The PEPITES Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (12-03-2019)“…IMPORTANCE: There are currently no approved treatments for peanut allergy. OBJECTIVE: To assess the efficacy and adverse events of epicutaneous immunotherapy…”
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Short-term ibrutinib therapy suppresses skin test responses and eliminates IgE-mediated basophil activation in adults with peanut or tree nut allergy
Published in Journal of allergy and clinical immunology (01-05-2018)“…[...]IgE-mediated BAT responses began to recover within days after cessation of ibrutinib treatment, and all were back to baseline within 1 week for all…”
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Asthma phenotypes in inner-city children
Published in Journal of allergy and clinical immunology (01-10-2016)“…Background Children with asthma in low-income urban areas have high morbidity. Phenotypic analysis in these children is lacking, but may identify…”
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Pathways through which asthma risk factors contribute to asthma severity in inner-city children
Published in Journal of allergy and clinical immunology (01-10-2016)“…Background Pathway analyses can be used to determine how host and environmental factors contribute to asthma severity. Objective To investigate pathways…”
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Safety, clinical, and immunologic efficacy of a Chinese herbal medicine (Food Allergy Herbal Formula-2) for food allergy
Published in Journal of allergy and clinical immunology (01-10-2015)“…Background Food Allergy Herbal Formula-2 (FAHF-2) is a 9-herb formula based on traditional Chinese medicine that blocks peanut-induced anaphylaxis in a murine…”
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Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial
Published in The Lancet (British edition) (13-08-2022)“…Black and Hispanic children living in urban environments in the USA have an excess burden of morbidity and mortality from asthma. Therapies directed at the…”
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Individualized Therapy for Persistent Asthma in Young Children
Published in Journal of allergy and clinical immunology (01-12-2016)“…Abstract Background Phenotypic presentations in young children with asthma are varied and may contribute to differential responses to asthma controller…”
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14
Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children
Published in Nature communications (24-02-2015)“…Food allergy (FA) affects 2%–10% of US children and is a growing clinical and public health problem. Here we conduct the first genome-wide association study of…”
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Effect of Varying Doses of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Exposure Among Patients With Peanut Sensitivity: A Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (14-11-2017)“…IMPORTANCE: Epicutaneous immunotherapy may have potential for treating peanut allergy but has been assessed only in preclinical and early human trials…”
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Distinguishing characteristics of difficult-to-control asthma in inner-city children and adolescents
Published in Journal of allergy and clinical immunology (01-10-2016)“…Background Treatment levels required to control asthma vary greatly across a population with asthma. The factors that contribute to variability in treatment…”
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Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children
Published in Nature immunology (01-05-2019)“…Respiratory infections are common precursors to asthma exacerbations in children, but molecular immune responses that determine whether and how an infection…”
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Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (17-11-2015)“…IMPORTANCE: Many preschool children develop recurrent, severe episodes of lower respiratory tract illness (LRTI). Although viral infections are often present,…”
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Coconut allergy: Characteristics of reactions and diagnostic predictors in a pediatric tertiary care center
Published in Annals of allergy, asthma, & immunology (01-05-2021)“…Little is known on the clinical manifestations of coconut allergy. Our knowledge to date is mainly based on case reports. To characterize the allergic…”
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Development and validation of the Composite Asthma Severity Index—an outcome measure for use in children and adolescents
Published in Journal of allergy and clinical immunology (01-03-2012)“…Background Asthma severity is reflected in many aspects of the disease, including impairment and future risks, particularly for exacerbations. According to the…”
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