Search Results - "Pongrácz, Judit E."

The PARP inhibitor rucaparib blocks SARS‐CoV‐2 virus binding to cells and the immune reaction in models of COVID‐19 by Papp, Henrietta, Tóth, Emese, Bóvári‐Biri, Judit, Bánfai, Krisztina, Juhász, Péter, Mahdi, Mohamed, Russo, Lilian Cristina, Bajusz, Dávid, Sipos, Adrienn, Petri, László, Szalai, Tibor Viktor, Kemény, Ágnes, Madai, Mónika, Kuczmog, Anett, Batta, Gyula, Mózner, Orsolya, Vaskó, Dorottya, Hirsch, Edit, Bohus, Péter, Méhes, Gábor, Tőzsér, József, Curtin, Nicola J., Helyes, Zsuzsanna, Tóth, Attila, Hoch, Nicolas C., Jakab, Ferenc, Keserű, György M., Pongrácz, Judit E., Bai, Péter

“…Background and Purpose To date, there are limited options for severe Coronavirus disease 2019 (COVID‐19), caused by SARS‐CoV‐2 virus. As ADP‐ribosylation…”
Get full text

In vivo and in vitro investigation of anti-inflammatory and mucus-regulatory activities of a fixed combination of thyme and primula extracts by Seibel, Jan, Kryshen, Kirill, Pongrácz, Judit E., Lehner, Martin D.

“…Hypersecretion of viscous mucus is one of the hallmark symptoms of acute and chronic bronchitis and typically develops secondary to an inflammation of the…”
Get full text

Role of CD248 as a potential severity marker in idiopathic pulmonary fibrosis by Bartis, Domokos, Crowley, Louise E, D'Souza, Vijay K, Borthwick, Lee, Fisher, Andrew J, Croft, Adam P, Pongrácz, Judit E, Thompson, Richard, Langman, Gerald, Buckley, Christopher D, Thickett, David R

“…CD248 or Endosialin is a transmembrane molecule expressed in stromal cells binding to extracellular matrix (ECM) components. It has been previously implicated…”
Get full text

The scaffold protein Tks4 is required for the differentiation of mesenchymal stromal cells (MSCs) into adipogenic and osteogenic lineages by Dülk, Metta, Kudlik, Gyöngyi, Fekete, Anna, Ernszt, Dávid, Kvell, Krisztián, Pongrácz, Judit E., Merő, Balázs L., Szeder, Bálint, Radnai, László, Geiszt, Miklós, Csécsy, Dalma E., Kovács, Tamás, Uher, Ferenc, Lányi, Árpád, Vas, Virag, Buday, László

“…The commitment steps of mesenchymal stromal cells (MSCs) to adipogenic and other lineages have been widely studied but not fully understood. Therefore, it is…”
Get full text

Toxicology studies of primycin-sulphate using a three-dimensional (3D) in vitro human liver aggregate model by Pénzes, Ágota, Mahmud Abdelwahab, Elhusseiny Mohamed, Rapp, Judit, Péteri, Zsanett A., Bovári-Biri, Judit, Fekete, Csaba, Miskei, György, Kvell, Krisztián, Pongrácz, Judit E.

“…•Primycin is an antibiotic with broad antimicrobial spectrum.•Primycin-sulphate at 1μg/ml and below did not show cytotoxicity in human liver aggregate…”
Get full text

Cell death and survival following manual and femtosecond laser-assisted capsulotomy in age-related cataract by Sükösd, Andrea Krisztina, Rapp, Judit, Feller, Diána, Sétáló, Jr, György, Gáspár, Beáta, Pongrácz, Judit E, Ábrahám, Hajnalka, Biró, Zsolt

“…To study molecular and morphological changes in lens epithelial cells following femtosecond laser-assisted and manually performed continuous curvilinear…”
Get full text

Expression of the Somatostatin Receptor Subtype 4 in Intact and Inflamed Pulmonary Tissues by Varecza, Zoltan, Elekes, Krisztian, Laszlo, Terezia, Perkecz, Aniko, Pinter, Erika, Sandor, Zoltan, Szolcsanyi, Janos, Keszthelyi, Daniel, Szabo, Arpad, Sandor, Katalin, Molnar, Tamas F, Szanto, Zalan, Pongracz, Judit E, Helyes, Zsuzsanna

“…Somatostatin released from capsaicin-sensitive sensory nerves of the lung during endotoxin-induced murine pneumonitis inhibits inflammation and…”
Get full text

Characterisation of eGFP-transgenic BALB/c mouse strain established by lentiviral transgenesis by Kvell, Krisztián, Czömpöly, Tamás, Hiripi, László, Balogh, Péter, Kóbor, József, Bodrogi, Lilla, Pongrácz, Judit E., Ritchie, William A., Bősze, Zsuzsanna

“…Lentiviral technology is a powerful tool for the creation of stable transgenic animals. However, uncertainties have remained whether constitutive promoters…”
Get full text

WNT signaling - lung cancer is no exception by Rapp, Judit, Jaromi, Luca, Kvell, Krisztian, Miskei, Gyorgy, Pongracz, Judit E

“…Since the initial discovery of the oncogenic activity of WNT ligands our understanding of the complex roles for WNT signaling pathways in lung cancers has…”
Get full text

Physical Activity as a Preventive Lifestyle Intervention Acts Through Specific Exosomal miRNA Species—Evidence From Human Short- and Long-Term Pilot Studies by Garai, Kitti, Adam, Zoltan, Herczeg, Robert, Banfai, Krisztina, Gyebrovszki, Adam, Gyenesei, Attila, Pongracz, Judit E., Wilhelm, Marta, Kvell, Krisztian

“…Exercise initiates systemic adaptation to promote health and prevent various lifestyle-related chronic diseases. Emerging evidence suggests that circulating…”
Get full text

Transgenic Exosomes for Thymus Regeneration by Banfai, Krisztina, Garai, Kitti, Ernszt, David, Pongracz, Judit E, Kvell, Krisztian

“…During senescence, Wnt4 expression is down-regulated (unlike their Frizzled receptors), while PPARgamma expression increases in the thymus. Together, these…”
Get full text

Cigarette Smoke-Induced Pulmonary Inflammation Becomes Systemic by Circulating Extracellular Vesicles Containing Wnt5a and Inflammatory Cytokines by Feller, Diana, Kun, Jozsef, Ruzsics, Istvan, Rapp, Judit, Sarosi, Veronika, Kvell, Krisztian, Helyes, Zsuzsanna, Pongracz, Judit E

“…Chronic obstructive pulmonary disease (COPD) is a devastating, irreversible pathology affecting millions of people worldwide. Clinical studies show that…”
Get full text

miRNAs as Predictors of Barrier Integrity by Bovari-Biri, Judit, Garai, Kitti, Banfai, Krisztina, Csongei, Veronika, Pongracz, Judit E

“…The human body has several barriers that protect its integrity and shield it from mechanical, chemical, and microbial harm. The various barriers include the…”
Get full text

Comprehensive Study of Mechanical, Electrical and Biological Properties of Conductive Polymer Composites for Medical Applications through Additive Manufacturing by Paari-Molnar, Emese, Kardos, Kinga, Told, Roland, Simon, Imre, Sahai, Nitin, Szabo, Peter, Bovari-Biri, Judit, Steinerbrunner-Nagy, Alexandra, Pongracz, Judit E, Rendeki, Szilard, Maroti, Peter

“…Conductive polymer composites are commonly present in flexible electrodes for neural interfaces, implantable sensors, and aerospace applications. Fused…”
Get full text

Corrigendum: Physical Activity as a Preventive Lifestyle Intervention Acts Through Specific Exosomal miRNA Species—Evidence From Human Short- and Long-Term Pilot Studies by Garai, Kitti, Adam, Zoltan, Herczeg, Robert, Banfai, Krisztina, Gyebrovszki, Adam, Gyenesei, Attila, Pongracz, Judit E., Wilhelm, Marta, Kvell, Krisztian

Get full text

Wnt4 and LAP2alpha as pacemakers of thymic epithelial senescence by Kvell, Krisztian, Varecza, Zoltan, Bartis, Domokos, Hesse, Sebastian, Parnell, Sonia, Anderson, Graham, Jenkinson, Eric J, Pongracz, Judit E

“…Age-associated thymic involution has considerable physiological impact by inhibiting de novo T-cell selection. This impaired T-cell production leads to…”
Get full text

Wnt signalling in lung development and diseases by Pongracz, Judit E, Stockley, Robert A

“…There are several signalling pathways involved in lung organogenesis including Notch, TGFbeta/BMP, Sonic hedgehog (Shh), FGF, EGF, and Wnt. Despite the widely…”
Get full text

Prdx5 in the Regulation of Tuberous Sclerosis Complex Mutation-Induced Signaling Mechanisms by Bovari-Biri, Judit, Abdelwahab, ElHusseiny Mohamed Mahmoud, Garai, Kitti, Pongracz, Judit E

“…(1) Background: Tuberous sclerosis complex (TSC) mutations directly affect mTORC activity and, as a result, protein synthesis. In several cancer types, TSC…”
Get full text

Normalization of Enzyme Expression and Activity Regulating Vitamin A Metabolism Increases RAR-Beta Expression and Reduces Cellular Migration and Proliferation in Diseases Caused by Tuberous Sclerosis Gene Mutations by Abdelwahab, Elhusseiny Mohamed Mahmoud, Bovari-Biri, Judit, Smuk, Gabor, Harko, Tunde, Fillinger, Janos, Moldvay, Judit, Krymskaya, Vera P, Pongracz, Judit E

“…Mutation in a tuberous sclerosis gene (TSC1 or 2) leads to continuous activation of the mammalian target of rapamycin (mTOR). mTOR activation alters cellular…”
Get full text

PPARgamma Deficiency Counteracts Thymic Senescence by Ernszt, David, Banfai, Krisztina, Kellermayer, Zoltan, Pap, Attila, Lord, Janet M, Pongracz, Judit E, Kvell, Krisztian

“…Thymic senescence contributes to increased incidence of infection, cancer and autoimmunity at senior ages. This process manifests as adipose involution. As…”
Get full text