Search Results - "Ponczek, Michał"

Blood Coagulation Activities of Cotton-Alginate-Copper Composites by Mrozińska, Zdzisława, Ponczek, Michał, Kaczmarek, Anna, Boguń, Maciej, Sulak, Edyta, Kudzin, Marcin H

“…Alginate-based materials have gained significant attention in the medical industry due to their biochemical properties. In this article, we aimed to synthesize…”
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Extracts from Uncaria tomentosa as antiplatelet agents and thrombin inhibitors – The in vitro and in silico study by Kolodziejczyk-Czepas, Joanna, Ponczek, Michał, Sady-Janczak, Magdalena, Pilarski, Radosław, Bukowska, Bożena

“…A wide range of traditional medicine applications of Uncaria tomentosa (Willd. ex Schult.) DC., commonly known as ‘vilcacora’ or ‘cat's claw’, includes blood…”
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High Molecular Weight Kininogen: A Review of the Structural Literature by Ponczek, Michał B

“…Kininogens are multidomain glycoproteins found in the blood of most vertebrates. High molecular weight kininogen demonstrate both carrier and co-factor…”
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Antagonists of Vitamin K-Popular Coumarin Drugs and New Synthetic and Natural Coumarin Derivatives by Kasperkiewicz, Kinga, Ponczek, Michał B, Owczarek, Jacek, Guga, Piotr, Budzisz, Elżbieta

“…Many natural coumarins and their chemically synthesized analogs and derivatives exert diverse properties, such as anticancer, antioxidant, anti-inflammatory,…”
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Finding inhibitors for PCSK9 using computational methods by Zainab, Rida, Kaleem, Afshan, Ponczek, Michal B, Abdullah, Roheena, Iqtedar, Mehwish, Hoessli, Daniel C

“…Proprotein convertase subtilisin/kexin type 9 (PCSK9) is one of the key targets for atherosclerosis drug development as its binding with low-density…”
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The synthesis of proteins in unnucleated blood platelets by Bijak, Michał, Saluk, Joanna, Ponczek, Michał Błażej Ponczek, Nowak, Paweł, Wachowicz, Barbara

“…Platelets are the smallest, unnucleated blood cells that play a key role in maintaining normal hemostasis. In the human body about 1x1011 platelets are formed…”
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Effects of Rheum rhaponticum and Rheum rhabarbarum extracts on haemostatic activity of blood plasma components and endothelial cells in vitro by Liudvytska, Oleksandra, Ponczek, Michał B., Krzyżanowska-Kowalczyk, Justyna, Kowalczyk, Mariusz, Balcerczyk, Aneta, Kolodziejczyk-Czepas, Joanna

“…Traditional medicine recommends the use of Rheum rhaponticum L. and R. rhabarbarum L. to treat over thirty complaints, including disorders related to the…”
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Reviews The role of fibrinogen, fibrin and fibrin(ogen) degradation products (FDPs) in tumor progression by Kołodziejczyk, Joanna, Ponczek, Michał B.

“…Participation of fibrin, fibrinogen, and their degradation products in pathogenesis and progression of cancer may lead to complications of thromboembolic…”
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Biochemical Approach to Poly(Lactide)-Copper Composite-Impact on Blood Coagulation Processes by Mrozińska, Zdzisława, Kudzin, Marcin H, Ponczek, Michał B, Kaczmarek, Anna, Król, Paulina, Lisiak-Kucińska, Agnieszka, Żyłła, Renata, Walawska, Anetta

“…The paper presents the investigation of the biological properties of Poly(Lactide)-Copper composite material obtained by sputter deposition of copper onto…”
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A biological, fluorescence and computational examination of synthetic coumarin derivatives with antithrombotic potential by Kasperkiewicz, Kinga, Ponczek, Michal B, Budzisz, Elzbieta

“…Scientists still look for new drugs, which have anticoagulant properties. This is so important because existing anticoagulant drugs give many side effects, for…”
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Rheum rhaponticum and Rheum rhabarbarum Extracts as Modulators of Endothelial Cell Inflammatory Response by Liudvytska, Oleksandra, Ponczek, Michał B, Ciesielski, Oskar, Krzyżanowska-Kowalczyk, Justyna, Kowalczyk, Mariusz, Balcerczyk, Aneta, Kolodziejczyk-Czepas, Joanna

“…Inflammation, endothelial dysfunction, and alterations in blood physiology are key factors contributing to atherosclerosis and other cardiovascular disorders…”
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Oxidative modification of patient's plasma proteins and its role in pathogenesis of multiple sclerosis by Miller, Elżbieta, Walczak, Anna, Saluk, Joanna, Ponczek, Michał B., Majsterek, Ireneusz

“…Oxidative stress plays an important role in multiple sclerosis (MS). The present study was designed to evaluate the modifications of plasma proteins by…”
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Flavonol and A-type procyanidin-rich extracts of Prunus spinosa L. flower exhibit anticoagulant activity through direct thrombin inhibition, but do not affect platelet aggregation in vitro by Marchelak, Anna, Kolodziejczyk-Czepas, Joanna, Ponczek, Michał B, Liudvytska, Oleksandra, Markowicz-Piasecka, Magdalena, Bielska, Beata, Miłowska, Katarzyna, Olszewska, Monika A

“…Blackthorn flower ( L.) is a traditional herbal remedy recommended for treating cardiovascular diseases (CVDs). This study investigates the effects of flavonol…”
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Pulmonaria obscura and Pulmonaria officinalis Extracts as Mitigators of Peroxynitrite-Induced Oxidative Stress and Cyclooxygenase-2 Inhibitors-In Vitro and In Silico Studies by Krzyżanowska-Kowalczyk, Justyna, Kowalczyk, Mariusz, Ponczek, Michał B, Pecio, Łukasz, Nowak, Paweł, Kolodziejczyk-Czepas, Joanna

“…The species (lungwort) are edible plants and traditional remedies for different disorders of the respiratory system. Our work covers a comparative study on…”
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The evolution of factor XI and the kallikrein-kinin system by Ponczek, Michał B., Shamanaev, Aleksandr, LaPlace, Alec, Dickeson, S. Kent, Srivastava, Priyanka, Sun, Mao-fu, Gruber, Andras, Kastrup, Christian, Emsley, Jonas, Gailani, David

“…Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of…”
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Interaction of Arylidenechromanone/Flavanone Derivatives with Biological Macromolecules Studied as Human Serum Albumin Binding, Cytotoxic Effect, Biocompatibility Towards Red Blood Cells by Adamus-Grabicka, Angelika A, Markowicz-Piasecka, Magdalena, Ponczek, Michał B, Kusz, Joachim, Małecka, Magdalena, Krajewska, Urszula, Budzisz, Elzbieta

“…The aim of this study was to determine the cytotoxic effect of 3-arylidenechromanone (1) and 3arylideneflavanone (2) on HL-60 and NALM-6 cell lines (two human…”
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The susceptibility of plasma coagulation factor XI to nitration and peroxynitrite action by Ponczek, Michaſ Bſażej

“…Coagulation factor XI is present in blood plasma as the zymogen, like other serine proteases of hemostatic system, but as the only coagulation factor forms…”
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Antithrombin Effect of Polyphenol-Rich Extracts from Black Chokeberry and Grape Seeds by Bijak, Michał, Saluk, Joanna, Ponczek, Michał Błażej, Nowak, Paweł

“…Thrombin is a serine protease that cleaves the peptide bonds in proteins located on the carboxyl side of arginine. Thrombin plays a central role in…”
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Radical scavenging and antioxidant effects of Matricaria chamomilla polyphenolic-polysaccharide conjugates by Kolodziejczyk-Czepas, Joanna, Bijak, Michal, Saluk, Joanna, Ponczek, Michal B, Zbikowska, Halina M, Nowak, Pawel, Tsirigotis-Maniecka, Marta, Pawlaczyk, Izabela

“…Matricaria chamomilla L. (MC), a member of the Asteraceae family, is one of the oldest medicinal plants, widely used worldwide for a variety of healing…”
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Bufadienolides from Kalanchoe daigremontiana modulate the enzymatic activity of plasmin - In vitro and in silico analyses by Kolodziejczyk-Czepas, Joanna, Pasiński, Bartłomiej, Ponczek, Michal B., Moniuszko-Szajwaj, Barbara, Kowalczyk, Mariusz, Pecio, Łukasz, Nowak, Pawel, Stochmal, Anna

“…Plasmin (EC 3.4.21.7) is a key enzyme of the fibrinolytic system, responsible for the degradation of fibrin clot and maintaining blood fluidity. Hence,…”
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