Search Results - "Poncy, J L"

Cobalt toxicity: Chemical and radiological combined effects on HaCaT keratinocyte cell line by Gault, N., Sandre, C., Poncy, J.-L., Moulin, C., Lefaix, J.-L., Bresson, C.

“…Cobalt (Co) is an essential trace element well known as a constituent of vitamin B 12, but different compounds of Co are also described as highly toxic and/or…”
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STRUCTURE OF A SINGLE MODEL TO DESCRIBE PLUTONIUM AND AMERICIUM DECORPORATION BY DTPA TREATMENTS by Fritsch, P, Sérandour, A. L, Grémy, O, Phan, G, Tsapis, N, Fattal, E, Benech, H, Deverre, J. R, Poncy, J. L

“…The aim of this study is to propose a single modeling structure to describe both plutonium and americium decorporation by DTPA, which is based on hypotheses…”
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LATE-OCCURRING PULMONARY PATHOLOGIES FOLLOWING INHALATION OF MIXED OXIDE (URANIUM + PLUTONIUM OXIDE) AEROSOL IN THE RAT by Griffiths, N. M, Van der Meeren, A, Fritsch, P, Abram, M.-C, Bernaudin, J.-F, Poncy, J. L

“…Accidental exposure by inhalation to alpha-emitting particles from mixed oxide (MOXuranium and plutonium oxide) fuels is a potential long-term health risk to…”
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A comparison of cellular irradiation techniques with alpha particles using the Geant4 Monte Carlo simulation toolkit by Incerti, S., Gault, N., Habchi, C., Lefaix, J. L., Moretto, Ph, Poncy, J. L., Pouthier, T., Seznec, H.

“…A comparison of three cellular irradiation techniques using the Monte Carlo simulation toolkit Geant4 is presented in this paper. They involve electrodeposited…”
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The effect of 50 Hz electromagnetic fields on the formation of micronuclei in rodent cell lines exposed to gamma radiation by LAGROYE, I, PONCY, J. L

“…Low frequency electromagnetic fields (EMF) do not produce enough energy to damage DNA, in contrast to ionizing radiations. Any relationship between increased…”
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Ultrastructural apoptotic lesions induced in bone marrow after neptunium-237 contamination by Pusset, D, Boulahdour, H, Fromm, M, Poncy, J L, Kantelip, B, Griffond, B, Baud, M, Galle, P

“…This study describes the ultrastructure of lesions induced by neptunium-237 (237Np), a by-product of uranium in nuclear reactors, in the bone marrow. A group…”
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Ultrastructural lesions induced by neptunium-237: apoptosis or necrosis? by Pusset, D, Fromm, M, Poncy, J L, Kantelip, B, Galle, P, Chambaudet, A, Baud, M, Boulahdour, H

“…In this study, we are concerned with the 237 isotope of neptunium (237Np), which is a by-product of uranium in nuclear reactors. To study ultrastructural…”
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Evaluation of the efficiency of DTPA and other new chelating agents for removing neptunium from target organs by PAQUET, H. METIVIER, J. L. PONCY, R. BURGADA and T. BAILLY, F.

“…Diethylenetriamine pentaacetic acid (DTPA) has been tested with 8 other new chelators for neptunium decorporation after systemic contamination in the rat. The…”
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Simplified Structure of a New Model to Describe Urinary Excretion of Plutonium after Systemic, Liver or Pulmonary Contamination of Rats Associated with Ca-DTPA Treatments by Fritsch, P., Sérandour, A. L., Grémy, O., Phan, G., Tsapis, N., Abram, M. C., Renault, D., Fattal, E., Benech, H., Deverre, J. R., Poncy, J. L.

“…Fritsch, P., Sérandour, A. L., Grémy, O., Phan, G., Tsapis, N., Abram, M. C., Renault, D., Fattal, E., Benech, H., Deverre, J. R. and Poncy, J. L. Simplified…”
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Radionuclide Biokinetics Database by Bailey, M.R., Ansoborlo, E., Kreyling, W.G., Newton, D., Poncy, J-L., Stradling, N., Taylor, D.M.

“…One task of the EULEP-EURADOS Action Group on Parameter Values for the Human Respiratory Tract Model was to collate published information on experimental…”
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MADOR: a new tool to calculate decrease of effective doses in human after DTPA therapy by Fritsch, P, Grémy, O, Hurtgen, C, Bérard, P, Grappin, L, Poncy, J L

“…Abstract models have been developed to describe dissolution of Pu/Am/Cm after internal contamination by inhalation or wound, chelation of actinides by…”
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Transfer of Polonium, Neptunium, Plutonium and Americium to the Primate Fetus by Paquet, F., Poncy, J.-L., Ham, G.J., Prosser, S.L., Harrison, J.D.

“…Two baboons in the fifth month of pregnancy were given a single intravenous injection of a mixture of 210Po, 237Np, 239Pu and 241Am in citrate solution. Total…”
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In Vitro and In Vivo Assessment of Plutonium Speciation and Decorporation in Blood and Target Retention Tissues after a Systemic Contamination followed by an Early Treatment with DTPA by Sérandour, A. L., Grémy, O., Fréchou, M., Renault, D., Poncy, J. L., Fritsch, P.

“…Sérandour, A. L., Grémy, O., Fréchou, M., Renault, D., Poncy, J. L. and Fritsch, P. In Vitro and In Vivo Assessment of Plutonium Speciation and Decorporation…”
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Approaches for Experimental Evaluation of Chelating Agents by Stradling, G.N., Hengé-Napoli, M-H., Paquet, F., Poncy, J-L., Fritsch, P., Taylor, D.M.

“…In practice, the efficacies of clinically approved chelating agents and the testing of new substances are often best achieved by animal studies in which known…”
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Optimum Treatment Regimens with Animals by Stradling, G.N., Hengé-Napoli, M-H., Paquet, F., Poncy, J-L., Fritsch, P., Taylor, D.M.

“…This paper reviews the optimum treatment protocols that have been obtained to date after intakes of specified chemical forms of plutonium, americium, thorium,…”
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Efficacy of Localised DTPA Treatment for Decorporation of Np Injected Intramuscularly as Np(IV) or Np(V) by Ramounet, B., Matton, S., Grillon, G., Poncy, J.L., Fritsch, P.

“…The efficacy of DTPA treatment for intramuscularly administered Np(IV) citrate and Np(V) in 0.1 M HNO3 was investigated in rats. Chelation treatment was…”
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Intranuclear sites of Np 237 in mammalian cells: a study using electron microscopy and electron probe microanalysis by Boulahdour, H, Poncy, J L, Berry, J P, Galle, P

“…Two methods, electron microscopy and wavelength dispersive electron probe microanalysis, were used to determine the intracellular sites and chemical form of…”
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An interdisciplinary approach to investigate the impact of cobalt in a human keratinocyte cell line by Bresson, C., Lamouroux, C., Sandre, C., Tabarant, M., Gault, N., Poncy, J.L., Lefaix, J.L., Den Auwer, C., Spezia, R., Gaigeot, M.-P., Ansoborlo, E., Mounicou, S., Fraysse, A., Deves, G., Bacquart, T., Seznec, H., Pouthier, T., Moretto, P., Ortega, R., Lobinski, R., Moulin, C.

“…Since in nuclear power plants, risks of skin contact contamination by radiocobalt are significant, we focused on the impact of cobalt on a human cutaneous cell…”
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Apoptosis of rat kidney cells after 241-americium administration by Labéjof, L, Berry, J P, Duchambon, P, Poncy, J L, Galle, P

“…Tumors induction by americium is well known but there are no data on the biological effects of this radionucleide at subcellular level. In order to study the…”
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Long Term Pulmonary Retention of Inhaled Actinide Oxides in Non-Human Primates by Poncy, J.L., Massiot, P., Rateau, G., Guezingar, F., L'Huillier, I., Grillon, G., Dudoignon, N., Frot, C., Fritsch, P.

“…The pulmonary retention of poorly soluble inhaled particles of actinide oxides might induce a long-term risk of lung pathology. These non-stochastic effects…”
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