Search Results - "Ponchel, G."

Increased intestinal permeation and modulation of presystemic metabolism of resveratrol formulated into self-emulsifying drug delivery systems by Mamadou, G., Charrueau, C., Dairou, J., Limas Nzouzi, N., Eto, B., Ponchel, G.

“…[Display omitted] Despite various beneficial biological properties, resveratrol lacks therapeutic applications because of poor bioavailability due to variable…”
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Ex vivo permeation of tamoxifen and its 4-OH metabolite through rat intestine from lecithin/chitosan nanoparticles by Barbieri, S., Buttini, F., Rossi, A., Bettini, R., Colombo, P., Ponchel, G., Sonvico, F., Colombo, G.

“…[Display omitted] Tamoxifen citrate is an anticancer drug slightly soluble in water. Administered orally, it shows great intra- and inter-patient variations in…”
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Characterization and in vitro evaluation of a vaginal gel containing Lactobacillus crispatus for the prevention of gonorrhea by N'Guessan Gnaman, K.C., Bouttier, S., Yeo, A., Aka Any-Grah, A.A.S., Geiger, S., Huang, N., Nicolas, V., Villebrun, S., Faye-Kette, H., Ponchel, G., Koffi, A.A., Agnely, F.

“…[Display omitted] The increasing resistance of Neisseria gonorrhoeae to any current antibiotic treatment and the difficulties associated with the use of…”
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Interfacial Interaction between Transmembrane Ocular Mucins and Adhesive Polymers and Dendrimers Analyzed by Surface Plasmon Resonance by Bravo-Osuna, I., Noiray, M., Briand, E., Woodward, A. M., Argüeso, P., Martínez, I. T. Molina, Herrero-Vanrell, R., Ponchel, G.

“…ABSTRACT Purpose Development of the first in vitro method based on biosensor chip technology designed for probing the interfacial interaction phenomena between…”
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Molecular weight controls the elongation of oblate-shaped degradable poly(γ-benzyl-l-glutamate)nanoparticles by Cauchois, Olivier, Segura-Sanchez, F., Ponchel, G.

“…The shape of nanoparticles in drug targeting applications has been recently suggested as being an interesting parameter for modulating their fate in the body…”
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Thiol functionalized polymethacrylic acid-based hydrogel microparticles for oral insulin delivery by Sajeesh, S., Vauthier, C., Gueutin, C., Ponchel, G., Sharma, Chandra P.

“…In the present study thiol functionalized polymethacrylic acid–polyethylene glycol–chitosan (PCP)-based hydrogel microparticles were utilized to develop an…”
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Novel Water-Soluble Mucoadhesive Carbosilane Dendrimers for Ocular Administration by Bravo-Osuna, I, Vicario-de-la-Torre, M, Andrés-Guerrero, V, Sánchez-Nieves, J, Guzmán-Navarro, M, de la Mata, F. J, Gómez, R, de las Heras, B, Argüeso, P, Ponchel, G, Herrero-Vanrell, R, Molina-Martínez, I. T

“…The purpose of this research was to determine the potential use of water-soluble anionic and cationic carbosilane dendrimers (generations 1–3) as mucoadhesive…”
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In vitro evaluation of calcium binding capacity of chitosan and thiolated chitosan poly(isobutyl cyanoacrylate) core–shell nanoparticles by Bravo-Osuna, I., Millotti, G., Vauthier, C., Ponchel, G.

“…The ability of chitosan and its derivatives to bind cations is well known. Chitosan and thiolated chitosan were recently associated with poly(isobutyl…”
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Characterization of chitosan thiolation and application to thiol quantification onto nanoparticle surface by Bravo-Osuna, I., Teutonico, D., Arpicco, S., Vauthier, C., Ponchel, G.

“…The objective of the present work was to establish a simple and appropriated method for the quantification of thiol groups standing on the surface of…”
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Combined hydroxypropyl-β-cyclodextrin and poly(anhydride) nanoparticles improve the oral permeability of paclitaxel by AGÜEROS, M, RUIZ-GATON, L, VAUTHIER, C, BOUCHEMAL, K, ESPUELAS, S, PONCHEL, G, IRACHE, J. M

“…The aim of this work was to study the effect of the combination between 2-hydroxypropyl-beta-cyclodextrin (HPCD) and bioadhesive nanoparticles on the…”
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Tuning of shell and core characteristics of chitosan-decorated acrylic nanoparticles by Bravo-Osuna, I., Ponchel, G., Vauthier, C.

“…The aim of the work was to develop a new family of chitosan-coated acrylic nanoparticles to increase the specificity of absorption of drugs associated given by…”
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Cytotoxicity and cellular uptake of newly synthesized fucoidan-coated nanoparticles by Lira, M.C.B., Santos-Magalhães, N.S., Nicolas, V., Marsaud, V., Silva, M.P.C., Ponchel, G., Vauthier, C.

“…Cytotoxicity and internalization of nanoparticles interacting with J774 cells. Top: nanoparticles obtained by anionic emulsion polymerization with 0 (A), 25…”
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Modulation of the rheological and mucoadhesive properties of thermosensitive poloxamer-based hydrogels intended for the rectal administration of quinine by Koffi, A.A., Agnely, F., Ponchel, G., Grossiord, J.L.

“…The aim of this work was to formulate and characterize thermosensitive gels based on poloxamer 407, a thermosensitive polymer, and hydroxypropylmethylcellulose…”
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Specific permeability modulation of intestinal paracellular pathway by chitosan-poly(isobutylcyanoacrylate) core-shell nanoparticles by Bravo-Osuna, I., Vauthier, C., Chacun, H., Ponchel, G.

“…This work is focused on the evaluation of the in vitro permeation modulation of chitosan and thiolated chitosan (chitosan-TBA) coated…”
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Concentration and surface of absorption: Concepts and applications to gastrointestinal patches delivery by Teutonico, D., Montanari, S., Ponchel, G.

“…Gastrointestinal patches represent a novel multiparticulate drug delivery system able to increase the intestinal absorption of drugs with poor bioavailability…”
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siRNA associated with immunonanoparticles directed against cd99 antigen improves gene expression inhibition in vivo in Ewing's sarcoma by Ramon, A. L., Bertrand, J. R., de Martimprey, H., Bernard, G., Ponchel, G., Malvy, C., Vauthier, C.

“…Ewing's sarcoma is a rare, mostly pediatric bone cancer that presents a chromosome abnormality called EWS/Fli‐1, responsible for the development of the tumor…”
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Novel core(polyester)-shell(polysaccharide) nanoparticles: protein loading and surface modification with lectins by Rodrigues, J.S, Santos-Magalhães, N.S, Coelho, L.C.B.B, Couvreur, P, Ponchel, G, Gref, R

“…This study describes new lectin-decorated or protein-loaded nanoparticles with a hydrophobic poly(ε-caprolactone) (PCL) core and a hydrophilic dextran (Dex)…”
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Combined hydroxypropyl-β-cyclodextrin and poly(alkylcyanoacrylate) nanoparticles intended for oral administration of saquinavir by Boudad, H, Legrand, P, Lebas, G, Cheron, M, Duchêne, D, Ponchel, G

“…The aim of this study was to prepare and characterize an hydroxypropyl-β-cyclodextrin–saquinavir inclusion complex with the purpose of incorporating this…”
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In vitro and in vivo characteristics of a thermogelling and bioadhesive delivery system intended for rectal administration of quinine in children by Koffi, A.A., Agnely, F., Besnard, M., Kablan Brou, J., Grossiord, J.L., Ponchel, G.

“…The aim of this work was to improve the rectal bioavailability of quinine hydrochloride by designing thermosensitive and mucoadhesive gels intended for rectal…”
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Gliadin Nanoparticles as carriers for the oral administration of lipophilic drugs. Relationships between bioadhesion and pharmacokinetics by ARANGOA, Miguel Angel, CAMPANERO, Miguel Angel, RENEDO, Maria Jesus, PONCHEL, Gilles, IRACHE, Juan Manuel

“…The aim of this work was to evaluate the bioadhesive properties of non-hardened gliadin nanoparticles (NPs) and cross-linked gliadin nanoparticles (CL-NP) in…”
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