Search Results - "Ponchel, G"
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Increased intestinal permeation and modulation of presystemic metabolism of resveratrol formulated into self-emulsifying drug delivery systems
Published in International journal of pharmaceutics (15-04-2017)“…[Display omitted] Despite various beneficial biological properties, resveratrol lacks therapeutic applications because of poor bioavailability due to variable…”
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2
Ex vivo permeation of tamoxifen and its 4-OH metabolite through rat intestine from lecithin/chitosan nanoparticles
Published in International journal of pharmaceutics (01-08-2015)“…[Display omitted] Tamoxifen citrate is an anticancer drug slightly soluble in water. Administered orally, it shows great intra- and inter-patient variations in…”
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Characterization and in vitro evaluation of a vaginal gel containing Lactobacillus crispatus for the prevention of gonorrhea
Published in International journal of pharmaceutics (15-10-2020)“…[Display omitted] The increasing resistance of Neisseria gonorrhoeae to any current antibiotic treatment and the difficulties associated with the use of…”
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Interfacial Interaction between Transmembrane Ocular Mucins and Adhesive Polymers and Dendrimers Analyzed by Surface Plasmon Resonance
Published in Pharmaceutical research (01-08-2012)“…ABSTRACT Purpose Development of the first in vitro method based on biosensor chip technology designed for probing the interfacial interaction phenomena between…”
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5
Molecular weight controls the elongation of oblate-shaped degradable poly(γ-benzyl-l-glutamate)nanoparticles
Published in International journal of pharmaceutics (16-08-2013)“…The shape of nanoparticles in drug targeting applications has been recently suggested as being an interesting parameter for modulating their fate in the body…”
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6
Thiol functionalized polymethacrylic acid-based hydrogel microparticles for oral insulin delivery
Published in Acta biomaterialia (01-08-2010)“…In the present study thiol functionalized polymethacrylic acid–polyethylene glycol–chitosan (PCP)-based hydrogel microparticles were utilized to develop an…”
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7
Novel Water-Soluble Mucoadhesive Carbosilane Dendrimers for Ocular Administration
Published in Molecular pharmaceutics (06-09-2016)“…The purpose of this research was to determine the potential use of water-soluble anionic and cationic carbosilane dendrimers (generations 1–3) as mucoadhesive…”
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In vitro evaluation of calcium binding capacity of chitosan and thiolated chitosan poly(isobutyl cyanoacrylate) core–shell nanoparticles
Published in International journal of pharmaceutics (29-06-2007)“…The ability of chitosan and its derivatives to bind cations is well known. Chitosan and thiolated chitosan were recently associated with poly(isobutyl…”
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Characterization of chitosan thiolation and application to thiol quantification onto nanoparticle surface
Published in International journal of pharmaceutics (01-08-2007)“…The objective of the present work was to establish a simple and appropriated method for the quantification of thiol groups standing on the surface of…”
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10
Combined hydroxypropyl-β-cyclodextrin and poly(anhydride) nanoparticles improve the oral permeability of paclitaxel
Published in European journal of pharmaceutical sciences (05-11-2009)“…The aim of this work was to study the effect of the combination between 2-hydroxypropyl-beta-cyclodextrin (HPCD) and bioadhesive nanoparticles on the…”
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Tuning of shell and core characteristics of chitosan-decorated acrylic nanoparticles
Published in European journal of pharmaceutical sciences (01-02-2007)“…The aim of the work was to develop a new family of chitosan-coated acrylic nanoparticles to increase the specificity of absorption of drugs associated given by…”
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12
Cytotoxicity and cellular uptake of newly synthesized fucoidan-coated nanoparticles
Published in European journal of pharmaceutics and biopharmaceutics (01-09-2011)“…Cytotoxicity and internalization of nanoparticles interacting with J774 cells. Top: nanoparticles obtained by anionic emulsion polymerization with 0 (A), 25…”
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13
Modulation of the rheological and mucoadhesive properties of thermosensitive poloxamer-based hydrogels intended for the rectal administration of quinine
Published in European journal of pharmaceutical sciences (01-03-2006)“…The aim of this work was to formulate and characterize thermosensitive gels based on poloxamer 407, a thermosensitive polymer, and hydroxypropylmethylcellulose…”
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14
Specific permeability modulation of intestinal paracellular pathway by chitosan-poly(isobutylcyanoacrylate) core-shell nanoparticles
Published in European journal of pharmaceutics and biopharmaceutics (01-06-2008)“…This work is focused on the evaluation of the in vitro permeation modulation of chitosan and thiolated chitosan (chitosan-TBA) coated…”
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15
Concentration and surface of absorption: Concepts and applications to gastrointestinal patches delivery
Published in International journal of pharmaceutics (15-07-2011)“…Gastrointestinal patches represent a novel multiparticulate drug delivery system able to increase the intestinal absorption of drugs with poor bioavailability…”
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16
siRNA associated with immunonanoparticles directed against cd99 antigen improves gene expression inhibition in vivo in Ewing's sarcoma
Published in Journal of molecular recognition (01-07-2013)“…Ewing's sarcoma is a rare, mostly pediatric bone cancer that presents a chromosome abnormality called EWS/Fli‐1, responsible for the development of the tumor…”
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Novel core(polyester)-shell(polysaccharide) nanoparticles: protein loading and surface modification with lectins
Published in Journal of controlled release (19-09-2003)“…This study describes new lectin-decorated or protein-loaded nanoparticles with a hydrophobic poly(ε-caprolactone) (PCL) core and a hydrophilic dextran (Dex)…”
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Combined hydroxypropyl-β-cyclodextrin and poly(alkylcyanoacrylate) nanoparticles intended for oral administration of saquinavir
Published in International journal of pharmaceutics (07-05-2001)“…The aim of this study was to prepare and characterize an hydroxypropyl-β-cyclodextrin–saquinavir inclusion complex with the purpose of incorporating this…”
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In vitro and in vivo characteristics of a thermogelling and bioadhesive delivery system intended for rectal administration of quinine in children
Published in European journal of pharmaceutics and biopharmaceutics (01-05-2008)“…The aim of this work was to improve the rectal bioavailability of quinine hydrochloride by designing thermosensitive and mucoadhesive gels intended for rectal…”
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Gliadin Nanoparticles as carriers for the oral administration of lipophilic drugs. Relationships between bioadhesion and pharmacokinetics
Published in Pharmaceutical research (01-11-2001)“…The aim of this work was to evaluate the bioadhesive properties of non-hardened gliadin nanoparticles (NPs) and cross-linked gliadin nanoparticles (CL-NP) in…”
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