Search Results - "Pomeranz, Gideon"
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A microfluidic platform integrating functional vascularized organoids-on-chip
Published in Nature communications (16-02-2024)“…The development of vascular networks in microfluidic chips is crucial for the long-term culture of three-dimensional cell aggregates such as spheroids,…”
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Diverse species-specific phenotypic consequences of loss of function sorting nexin 14 mutations
Published in Scientific reports (13-08-2020)“…Mutations in the SNX14 gene cause spinocerebellar ataxia, autosomal recessive 20 (SCAR20) in both humans and dogs. Studies implicating the phenotypic…”
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Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice
Published in Scientific reports (16-07-2022)“…Plasma ultrafiltration in the kidney occurs across glomerular capillaries, which are surrounded by epithelial cells called podocytes. Podocytes have a unique…”
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Cardiotrophin‐1 therapy reduces disease severity in a murine model of glomerular disease
Published in Physiological reports (01-07-2024)“…Cardiotrophin‐1 (CT‐1), a member of the interleukin (IL)‐6 cytokine family, has renoprotective effects in mouse models of acute kidney disease and…”
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SGLT1 contributes to glucose-mediated exacerbation of ischemia–reperfusion injury in ex vivo rat heart
Published in Basic research in cardiology (01-10-2024)“…Hyperglycaemia is common during acute coronary syndromes (ACS) irrespective of diabetic status and portends excess infarct size and mortality, but the…”
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Single‐cell transcriptomics identifies aberrant glomerular angiogenic signalling in the early stages of WT1 kidney disease
Published in The Journal of pathology (01-10-2024)“…WT1 encodes a podocyte transcription factor whose variants can cause an untreatable glomerular disease in early childhood. Although WT1 regulates many podocyte…”
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