Search Results - "Pomara, N."

Abnormality in glutamine–glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study by Hashimoto, K, Bruno, D, Nierenberg, J, Marmar, C R, Zetterberg, H, Blennow, K, Pomara, N

“…Major depressive disorder (MDD), common in the elderly, is a risk factor for dementia. Abnormalities in glutamatergic neurotransmission via the N -methyl- d…”
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Decreased Recall of Primacy Words Predicts Cognitive Decline by BRUNO, Davide, REISS, Philip T, PETKOVA, Eva, SIDTIS, John J, POMARA, Nunzio

“…One of the cognitive changes associated with Alzheimer's disease is a diminution of the primacy effect, i.e., the tendency toward better recall of items…”
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Changes in cerebral neurotransmitters and metabolites induced by acute donepezil and memantine administrations: A microdialysis study by Shearman, E., Rossi, S., Szasz, B., Juranyi, Z., Fallon, S., Pomara, N., Sershen, H., Lajtha, A.

“…Cholinesterase inhibitors including donepezil, rivastigmine, and galantamine and the N-methyl- d-aspartate (NMDA) antagonist, memantine are the medications…”
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Association of CSF sTREM2, a marker of microglia activation, with cholinergic basal forebrain volume in major depressive disorder by Teipel, Stefan, Bruno, Davide, Plaska, Chelsea Reichert, Heslegrave, Amanda, Ramos-Cejudo, Jaime, Osorio, Ricardo S., Zetterberg, Henrik, Blennow, Kaj, Pomara, Nunzio

“…Inflammatory mechanisms are believed to contribute to the manifestation of major depressive disorder (MDD). Central cholinergic activity may moderate this…”
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Cross-Sectional Associations of CSF Tau Levels With Rey's AVLT: A Recency Ratio Study by Bruno, Davide, Jauregi Zinkunegi, Ainara, Pomara, Nunzio, Zetterberg, Henrik, Blennow, Kaj, Koscik, Rebecca Langhough, Carlsson, Cynthia, Bendlin, Barbara, Okonkwo, Ozioma, Hermann, Bruce P., Johnson, Sterling C., Mueller, Kimberly D.

“…Objective: The preeminent in vivo cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) are amyloid β 1-42 (Aβ42), phosphorylated Tau (p-tau), and…”
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CSF butyrylcholinesterase and acetylcholinesterase activity and their relationship to pro-inflammatory cytokines in late-life major depression by Pomara, N., Bruno, D., Nierenberg, J., Reichert, C., Fu, M., Zetterberg, H., Blennow, K.

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Plasma Amyloid-β dynamics in late-life major depression: a longitudinal study by Pomara, Nunzio, Bruno, Davide, Plaska, Chelsea Reichert, Ramos-Cejudo, Jaime, Osorio, Ricardo S., Pillai, Anilkumar, Imbimbo, Bruno P., Zetterberg, Henrik, Blennow, Kaj

“…Depressed individuals are twice as likely to develop Alzheimer’s disease (AD) as compared to controls. Brain amyloid-β (Aβ) deposition is believed to have a…”
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A comparison of diagnostic performance of word-list and story recall tests for biomarker-determined Alzheimer's disease by Bruno, Davide, Jauregi Zinkunegi, Ainara, Kollmorgen, Gwendlyn, Carboni, Margherita, Wild, Norbert, Carlsson, Cynthia, Bendlin, Barbara, Okonkwo, Ozioma, Chin, Nathaniel, Hermann, Bruce P., Asthana, Sanjay, Blennow, Kaj, Langhough, Rebecca, Johnson, Sterling C., Pomara, Nunzio, Zetterberg, Henrik, Mueller, Kimberly D.

“…Wordlist and story recall tests are routinely employed in clinical practice for dementia diagnosis. In this study, our aim was to establish how well-standard…”
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Memantine treatment in mild to moderate Alzheimer disease: a 24-week randomized, controlled trial by Peskind, Elaine R, Potkin, Steven G, Pomara, Nunzio, Ott, Brian R, Graham, Stephen M, Olin, Jason T, McDonald, Scott

“…The objective of this study was to compare the efficacy and safety of the moderate-affinity, uncompetitive N-methyl-d-aspartate receptor antagonist, memantine,…”
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Cerebrospinal Fluid C3a Increases with Age, But Does Not Increase Further in Alzheimer’s Disease by Loeffler, D.A, Brickman, C.M, Juneau, P.L, Perry, M.F, Pomara, N, LeWitt, P.A

“…Complement activation is present in the brain in Alzheimer’s disease (AD), and C1q concentrations are decreased in AD cerebrospinal fluid (CSF). To determine…”
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Increased levels of ascorbic acid in the cerebrospinal fluid of cognitively intact elderly patients with major depression: a preliminary study by Hashimoto, Kenji, Ishima, Tamaki, Sato, Yasunori, Bruno, Davide, Nierenberg, Jay, Marmar, Charles R., Zetterberg, Henrik, Blennow, Kaj, Pomara, Nunzio

“…Major depressive disorder (MDD) in the elderly is a risk factor for dementia, but the precise biological basis remains unknown, hampering the search for novel…”
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Ceruloplasmin is increased in cerebrospinal fluid in Alzheimer's disease but not Parkinson's disease by Loeffler, D A, DeMaggio, A J, Juneau, P L, Brickman, C M, Mashour, G A, Finkelman, J H, Pomara, N, LeWitt, P A

“…Although the pathophysiology of Alzheimer's disease (AD) and Parkinson's disease (PD) is unknown, altered brain antioxidative mechanisms have been found in…”
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Suicidal behavior: a neglected issue in DSM-III by Pomara, N

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Transient elevations in pancreatic enzymes in response to a cholinesterase inhibitor by Pomara, N, Citrome, L

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Benzodiazepine Use and Crash Risk in Older Patients by Amoroso, Paul J, Reynolds, Katy L, Bell, Nicole S

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Reduced frontal white matter integrity in cocaine dependence: a controlled diffusion tensor imaging study by Lim, Kelvin O, Choi, Steven J, Pomara, Nunzio, Wolkin, Adam, Rotrosen, John P

“…Background: In vivo magnetic resonance studies have found that cocaine dependence is associated with T2 signal hyperintensities and metabolite abnormalities in…”
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Abnormal white matter integrity in healthy apolipoprotein E epsilon4 carriers by Nierenberg, Jay, Pomara, Nunzio, Hoptman, Matthew J, Sidtis, John J, Ardekani, Babak A, Lim, Kelvin O

“…Apolipoprotein E 4 is a major genetic risk factor for Alzheimerʼs disease, but the neurobiological basis for this risk is unknown. We used diffusion tensor…”
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Treatment-resistant depression in an elderly patient with pancreatic carcinoma: case report by POMARA, N, GERSHON, S

“…A case is reported of a recurrent and treatment-resistant depression with a positive DST in an individual in whom adenocarcinoma of the pancreas was eventually…”
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Pathophysiology of Alzheimer's disease by Imbimbo, Bruno P, Lombard, Jay, Pomara, Nunzio

“…Tremendous progress has been made in understanding the processes of the Alzheimer's disease (AD) cascade, laying the groundwork for improvements in diagnosis…”
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White matter abnormalities in HIV-1 infection: A diffusion tensor imaging study by Pomara, Nunzio, Crandall, David T., Choi, Steven J., Johnson, Glyn, Lim, Kelvin O.

“…Diffuse white matter pallor is the most frequent neuropathological feature of HIV-1 infection and has been found to be particularly prominent in the advanced…”
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