Search Results - "Poma, Alessandro"
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Advances in Molecularly Imprinted Polymers as Drug Delivery Systems
Published in Molecules (Basel, Switzerland) (11-06-2021)“…Despite the tremendous efforts made in the past decades, severe side/toxic effects and poor bioavailability still represent the main challenges that hinder the…”
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Molecularly Imprinted Polymers and Electrospinning: Manufacturing Convergence for Next‐Level Applications
Published in Advanced functional materials (01-08-2020)“…Micro‐ and especially nanofiber‐type of materials are extremely attractive for a number of applications, ranging from separation and analysis to drug delivery…”
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Molecular Targets for Antibody-Based Anti-Biofilm Therapy in Infective Endocarditis
Published in Polymers (05-08-2022)“…Infective endocarditis (IE) is a heart disease caused by the infection of heart valves, majorly caused by . IE is initiated by bacteria entering the blood…”
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Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions
Published in Nature communications (24-09-2020)“…From viruses to nanoparticles, constructs functionalized with multiple ligands display peculiar binding properties that only arise from multivalent effects…”
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Engineering Polymeric Nanosystems against Oral Diseases
Published in Molecules (Basel, Switzerland) (13-04-2021)“…Nanotechnology and nanoparticles (NPs) are at the forefront of modern research, particularly in the case of healthcare therapeutic applications. Polymeric NPs,…”
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Biodegradable and Sustainable Synthetic Antibodies-A Perspective
Published in Pharmaceutics (09-05-2023)“…Molecular imprinting technology has been around for almost a century, and we have witnessed dramatic advancements in the overall design and production of…”
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Metabolically Active, Fully Hydrolysable Polymersomes
Published in Angewandte Chemie International Edition (26-03-2019)“…The synthesis and aqueous self‐assembly of a new class of amphiphilic aliphatic polyesters are presented. These AB block polyesters comprise polycaprolactone…”
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Tuning cell behavior with nanoparticle shape
Published in PloS one (13-11-2020)“…We investigated how the shape of polymeric vesicles, made by the exact same material, impacts the replication activity and metabolic state of both cancer and…”
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LRP-1 functionalized polymersomes enhance the efficacy of carnosine in experimental stroke
Published in Scientific reports (20-01-2020)“…Stroke is one of the commonest causes of death with limited treatment options. L-Carnosine has shown great promise as a neuroprotective agent in experimental…”
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Macrophage Targeting pH Responsive Polymersomes for Glucocorticoid Therapy
Published in Pharmaceutics (15-11-2019)“…Glucocorticoid (GC) drugs are the cornerstone therapy used in the treatment of inflammatory diseases. Here, we report pH responsive poly(2-methacryloyloxyethyl…”
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Prostate cancer cell-specific BikDDA delivery by targeted polymersomes
Published in Applied nanoscience (01-09-2020)“…In this paper, we report the polymersome-mediated intracellular delivery of pro-apoptotic BikDDA gene using two different peptide–copolymer covalent…”
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Correction to: Prostate cancer cell-specific BikDDA delivery by targeted polymersomes
Published in Applied nanoscience (2020)“…Unfortunately, the Fig. 6 was published incorrectly in the online published article…”
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Solid-phase synthesis of molecularly imprinted nanoparticles
Published in Nature protocols (01-03-2016)“…Canfarotta et al . describe an elegant molecular imprinting method in which the target is immobilized on glass beads. These are then used to produce…”
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Molecularly Imprinted Polymers for Cell Recognition
Published in Trends in biotechnology (Regular ed.) (01-04-2020)“…Since their conception 50 years ago, molecularly imprinted polymers (MIPs) have seen extensive development both in terms of synthetic routes and applications…”
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Analytical methods for determination of mycotoxins: An update (2009–2014)
Published in Analytica chimica acta (11-12-2015)“…Mycotoxins are a problematic and toxic group of small organic molecules that are produced as secondary metabolites by several fungal species that colonise…”
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MIP sensors – the electrochemical approach
Published in Analytical and bioanalytical chemistry (01-02-2012)“…This review highlights the importance of coupling molecular imprinting technology with methodology based on electrochemical techniques for the development of…”
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Specific Drug Delivery to Cancer Cells with Double-Imprinted Nanoparticles against Epidermal Growth Factor Receptor
Published in Nano letters (08-08-2018)“…Epidermal growth factor receptor (EGFR), a tyrosine kinase receptor, is over-expressed in many tumors, including almost half of triple-negative breast cancers…”
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Molecular bionics – engineering biomaterials at the molecular level using biological principles
Published in Biomaterials (01-02-2019)“…Life and biological units are the result of the supramolecular arrangement of many different types of molecules, all of them combined with exquisite precision…”
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Solid-Phase Synthesis of Molecularly Imprinted Polymer Nanoparticles with a Reusable Template-"Plastic Antibodies"
Published in Advanced functional materials (13-06-2013)“…Molecularly imprinted polymers (MIPs) are generic alternatives to antibodies in sensors, diagnostics, and separations. To displace biomolecules without radical…”
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Advances in the manufacture of MIP nanoparticles
Published in Trends in biotechnology (Regular ed.) (01-12-2010)“…Molecularly imprinted polymers (MIPs) are prepared by creating a three-dimensional polymeric matrix around a template molecule. After the matrix is removed,…”
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