Search Results - "Polyak, K"

The role of the microenvironment in mammary gland development and cancer by Polyak, Kornelia, Kalluri, Raghu

“…The mammary gland is composed of a diverse array of cell types that form intricate interaction networks essential for its normal development and physiologic…”
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Re-emergence of Vibrio tubiashii in bivalve shellfish aquaculture : severity, environmental drivers, geographic extent and management by ELSTON, Ralph A, HASEGAWA, Hiroaki, HUMPHREY, Karen L, POLYAK, Ildiko K, HÄSE, Claudia C

“…During 2006 and 2007, we documented the re-emergence of severe episodes of vibriosis caused by Vibrio tubiashii in shellfish hatcheries on the west coast of…”
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PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling by Shrestha, Y, Schafer, E J, Boehm, J S, Thomas, S R, He, F, Du, J, Wang, S, Barretina, J, Weir, B A, Zhao, J J, Polyak, K, Golub, T R, Beroukhim, R, Hahn, W C

“…Activating mutations in the RAS family or BRAF frequently occur in many types of human cancers but are rarely detected in breast tumors. However, activation of…”
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Analytical validation of HER2DX genomic test for early-stage HER2-positive breast cancer by Marín-Aguilera, M., Jares, P., Sanfeliu, E., Villacampa, G., Hernández-lllán, E., Martínez-Puchol, A.I., Shankar, S., González-Farré, B., Waks, A.G., Brasó-Maristany, F., Pardo, F., Manning, D.K., Abery, J.A., Curaba, J., Moon, L., Gordon, O., Galván, P., Wachirakantapong, P., Castillo, O., Nee, C.M., Blasco, P., Senevirathne, T.H., Sirenko, V., Martínez-Sáez, O., Aguirre, A., Krop, I.E., Li, Z., Spellman, P., Metzger Filho, O., Polyak, K., Michaels, P., Puig-Butillé, J.A., Vivancos, A., Matito, J., Buckingham, W., Perou, C.M., Villagrasa-González, P., Prat, A., Parker, J.S., Paré, L.

“…HER2DX, a multianalyte genomic test, has been clinically validated to predict breast cancer recurrence risk (relapse risk score), the probability of achieving…”
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Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta by Reynisdóttir, I, Polyak, K, Iavarone, A, Massagué, J

“…G1 progression in mammalian cells requires the activity of the cyclin D-dependent kinases Cdk4 and/or Cdk6 and the cyclin E-dependent kinase Cdk2…”
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Detection of psoriasin/S100A7 in the sera of patients with psoriasis by Anderson, K.S., Wong, J., Polyak, K., Aronzon, D., Enerbäck, C.

“…Summary Background  Psoriasis is a disease of dysregulated inflammation and epithelial hyperproliferation in the skin, involving both the innate and adaptive…”
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Analysis of human transcriptomes by Velculescu, Victor E, Madden, Stephen L, Zhang, Lin, Lash, Alex E, Yu, Jian, Rago, Carlo, Lal, Anita, Wang, Clarence J, Beaudry, Gary A, Ciriello, Kristin M, Cook, Brian P, Dufault, Michael R, Ferguson, Anne T, Gao, Yuhong, He, Tong-Chuan, Hermeking, Heiko, Hiraldo, Siewleng K, Hwang, Paul M, Lopez, Marissa A, Luderer, Hilary F, Mathews, Brynna, Petroziello, Joseph M, Polyak, Kornelia, Zawel, Leigh, Zhang, Wen, Zhang, Xiaoming, Zhou, Wei, Haluska, Frank G, Jen, Jin, Sukumar, Saraswati, Landes, Gregory M, Riggins, Gregory J, Vogelstein, Bert, Kinzler, Kenneth W

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Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations by Lauring, J, Cosgrove, D P, Fontana, S, Gustin, J P, Konishi, H, Abukhdeir, A M, Garay, J P, Mohseni, M, Wang, G M, Higgins, M J, Gorkin, D, Reis, M, Vogelstein, B, Polyak, K, Cowherd, M, Buckhaults, P J, Park, B H

“…An oncogenic mutation (G49A:E17K) in the AKT1 gene has been described recently in human breast, colon, and ovarian cancers. The low frequency of this mutation…”
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Gene Discovery Using the Serial Analysis of Gene Expression Technique: Implications for Cancer Research by POLYAK, Kornelia, RIGGINS, Gregory J

“…Cancer is a genetic disease. As such, our understanding of the pathobiology of tumors derives from analyses of the genes whose mutations are responsible for…”
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Genetic determinants of p53-induced apoptosis and growth arrest by Polyak, K, Waldman, T, He, T C, Kinzler, K W, Vogelstein, B

“…Previous studies have suggested that expression of p53 in cancer cells can result in either growth arrest or apoptosis. Accordingly, expression of p53 in a…”
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Abstract BS1-2: Epigenetic targets in breast cancer by Polyak, K

“…Abstract Epigenetic regulators are emerging therapeutic targets in various human cancer types including breast cancer. Histone modification (e.g., methylation…”
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Abstract ES1-1: Non-cell-autonomous drivers of tumor growth and progression by Polyak, K

“…Abstract Cancer cells even within the same tumor can display startling differences for many features including migratory/invasive potential and sensitivity to…”
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Determination of surface properties of iron hydroxide-coated alumina adsorbent prepared for removal of arsenic from drinking water by Hlavay, József, Polyák, Klára

“…A novel type adsorbent was prepared by in situ precipitation of Fe(OH) 3 on the surface of activated Al 2O 3 as a support material. The iron content of the…”
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Molecular Markers for the Diagnosis and Management of Ductal Carcinoma In Situ by Polyak, Kornelia

“…Ductal carcinoma in situ (DCIS) is a heterogeneous group of lesions reflecting the proliferation of malignant cells within the ducts of the breast without…”
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Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia by Polyak, K, Hamilton, SR, Vogelstein, B, Kinzler, KW

“…Aberrant crypt foci with dysplasia are thought to be the first detectable lesions of colorectal neoplasia. Because cell cycle disruption appears crucial for…”
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Co-evolution of tumor cells and their microenvironment by Polyak, Kornelia, Haviv, Izhak, Campbell, Ian G

“…Increasing evidence indicates that tumor–stromal cell interactions have a crucial role in tumor initiation and progression. These interactions modify cellular…”
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Pregnancy and breast cancer: The other side of the coin by Polyak, Kornelia

“…Early full-term pregnancy is thought to be one of the most effective means of decreasing lifetime breast cancer risk. Paradoxically, young women diagnosed with…”
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Breast cancer stem cells by Polyak, K, Shipitsin, M, Campbell, L, Yao, J

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Roots and stems: stem cells in cancer by Polyak, Kornelia, Hahn, William C

“…Cancer develops from normal tissues through the accumulation of genetic alterations that act in concert to confer malignant phenotypes. Although we have now…”
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Size distributions of inorganic and organic species in the atmospheric aerosol in Hungary by Mészáros, E., Barcza, T., Gelencsér, A., Hlavay, J., Kiss, Gy, Krivácsy, Z., Molnár, A., Polyák, K.

“…Atmospheric aerosol samples were taken in different size intervals by means of a Berner-type cascade impactor. The samples were analyzed by using capillary…”
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