Search Results - "Polverino de' Laureto, Patrizia"

3,4‐Dihydroxyphenylethanol and 3,4‐dihydroxyphenylacetic acid affect the aggregation process of E46K variant of α‐synuclein at different extent: Insights into the interplay between protein dynamics and catechol effect by Fongaro, Benedetta, Cappelletto, Elia, Sosic, Alice, Spolaore, Barbara, Polverino de Laureto, Patrizia

“…Parkinson's disease (PD) is a chronic multifactorial disease, whose etiology is not completely understood. The amyloid aggregation of α‐synuclein (Syn) is…”
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Oxidation of Myofibrillar Proteins in Human Heart Failure by Canton, Marcella, PhD, Menazza, Sara, MSc, Sheeran, Freya L., PhD, Polverino de Laureto, Patrizia, PhD, Di Lisa, Fabio, MD, Pepe, Salvatore, PhD

“…Objectives We investigated the incidence and contribution of the oxidation/nitrosylation of tropomyosin and actin to the contractile impairment and…”
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α-Synuclein and Polyunsaturated Fatty Acids: Molecular Basis of the Interaction and Implication in Neurodegeneration by Fecchio, Chiara, Palazzi, Luana, de Laureto, Patrizia Polverino

“…α-Synuclein (α-syn) is a 140-amino acid protein, the physiological function of which has yet to be clarified. It is involved in several neurodegenerative…”
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A serine protease secreted from Bacillus subtilis cleaves human plasma transthyretin to generate an amyloidogenic fragment by Peterle, Daniele, Pontarollo, Giulia, Spada, Stefano, Brun, Paola, Palazzi, Luana, Sokolov, Alexej V., Spolaore, Barbara, Polverino de Laureto, Patrizia, Vasilyev, Vadim B., Castagliuolo, Ignazio, De Filippis, Vincenzo

“…Aggregation of human wild-type transthyretin (hTTR), a homo-tetrameric plasma protein, leads to acquired senile systemic amyloidosis (SSA), recently recognised…”
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Oleuropein aglycone stabilizes the monomeric α-synuclein and favours the growth of non-toxic aggregates by Palazzi, Luana, Bruzzone, Elena, Bisello, Giovanni, Leri, Manuela, Stefani, Massimo, Bucciantini, Monica, Polverino de Laureto, Patrizia

“…α-synuclein plays a key role in the pathogenesis of Parkinson’s disease (PD); its deposits are found as amyloid fibrils in Lewy bodies and Lewy neurites, the…”
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The Integrated Approach to Inherited Disorders in Neurotransmitters from Molecules to Systems by Bertoldi, Mariarita, Polverino de Laureto, Patrizia

“…This Special Issue focusses on monoamine neurotransmitters responsible for mediating neuronal transmission [...]…”
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C1q-Mediated Complement Activation and C3 Opsonization Trigger Recognition of Stealth Poly(2-methyl-2-oxazoline)-Coated Silica Nanoparticles by Human Phagocytes by Tavano, Regina, Gabrielli, Luca, Lubian, Elisa, Fedeli, Chiara, Visentin, Silvia, Polverino De Laureto, Patrizia, Arrigoni, Giorgio, Geffner-Smith, Alessandra, Chen, Fangfang, Simberg, Dmitri, Morgese, Giulia, Benetti, Edmondo M, Wu, Linping, Moghimi, Seyed Moein, Mancin, Fabrizio, Papini, Emanuele

“…Poly­(2-methyl-2-oxazoline) (PMOXA) is an alternative promising polymer to poly­(ethylene glycol) (PEG) for design and engineering of macrophage-evading…”
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The biological activities of protein/oleic acid complexes reside in the fatty acid by Fontana, Angelo, Spolaore, Barbara, Polverino de Laureto, Patrizia

“…A complex formed by human α-lactalbumin (α-LA) and oleic acid (OA), named HAMLET, has been shown to have an apoptotic activity leading to the selective death…”
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Proteomic Analysis of MeJa-Induced Defense Responses in Rice against Wounding by Bertini, Laura, Palazzi, Luana, Proietti, Silvia, Pollastri, Susanna, Arrigoni, Giorgio, Polverino de Laureto, Patrizia, Caruso, Carla

“…The role of jasmonates in defense priming has been widely recognized. Priming is a physiological process by which a plant exposed to low doses of biotic or…”
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C‐terminal tails mimicking bioactive intermediates cause different plasma degradation patterns and kinetics in neuropeptides γ‐MSH, α‐MSH, and neurotensin by Palazzi, Luana, Pasquato, Antonella, Vicario, Mattia, Roulin, Alexandre, Polverino de Laureto, Patrizia, Cendron, Laura

“…Peptides are attractive drugs because of their specificity and minimal off‐target effects. Short half‐lives are within their major drawbacks, limiting actual…”
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Axonal Odorant Receptors Mediate Axon Targeting by Zamparo, Ilaria, Francia, Simona, Franchi, Sira Angela, Redolfi, Nelly, Costanzi, Elisa, Kerstens, Axelle, Fukutani, Yosuke, Battistutta, Roberto, Polverino de Laureto, Patrizia, Munck, Sebastian, De Strooper, Bart, Matsunami, Hiroaki, Lodovichi, Claudia

“…In mammals, odorant receptors not only detect odors but also define the target in the olfactory bulb, where sensory neurons project to give rise to the sensory…”
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Fetal bovine serum contains biologically available ATP by Vultaggio-Poma, Valentina, Scussel Bergamin, Leticia, Falzoni, Simonetta, Tarantini, Mario, Giuliani, Anna Lisa, Sandonà, Dorianna, Polverino De Laureto, Patrizia, Di Virgilio, Francesco

“…ATP is a ubiquitous extracellular messenger released in a wide number of pathophysiological conditions. ATP is known to be present in minute amounts in the…”
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The Non-Core Regions of Human Lysozyme Amyloid Fibrils Influence Cytotoxicity by Mossuto, Maria F., Dhulesia, Anne, Devlin, Glyn, Frare, Erica, Kumita, Janet R., de Laureto, Patrizia Polverino, Dumoulin, Mireille, Fontana, Angelo, Dobson, Christopher M., Salvatella, Xavier

“…Identifying the cause of the cytotoxicity of species populated during amyloid formation is crucial to understand the molecular basis of protein deposition…”
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α-Synuclein oligomers induced by docosahexaenoic acid affect membrane integrity by Fecchio, Chiara, De Franceschi, Giorgia, Relini, Annalisa, Greggio, Elisa, Dalla Serra, Mauro, Bubacco, Luigi, Polverino de Laureto, Patrizia

“…A key feature of Parkinson disease is the aggregation of α-synuclein and its intracellular deposition in fibrillar form. Increasing evidence suggests that the…”
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Characterization of Oligomeric Species on the Aggregation Pathway of Human Lysozyme by Frare, Erica, Mossuto, Maria F., de Laureto, Patrizia Polverino, Tolin, Serena, Menzer, Linda, Dumoulin, Mireille, Dobson, Christopher M., Fontana, Angelo

“…The aggregation process of wild-type human lysozyme at pH 3.0 and 60 °C has been analyzed by characterizing a series of distinct species formed on the…”
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Biodiversity and Bioprospecting of Fungal Endophytes from the Antarctic Plant Colobanthus quitensis by Bertini, Laura, Perazzolli, Michele, Proietti, Silvia, Capaldi, Gloria, Savatin, Daniel V., Bigini, Valentina, Longa, Claudia Maria Oliveira, Basaglia, Marina, Favaro, Lorenzo, Casella, Sergio, Fongaro, Benedetta, Polverino de Laureto, Patrizia, Caruso, Carla

“…Microorganisms from extreme environments are considered as a new and valuable reservoir of bioactive molecules of biotechnological interest and are also…”
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Identification of the Core Structure of Lysozyme Amyloid Fibrils by Proteolysis by Frare, Erica, Mossuto, Maria F., Polverino de Laureto, Patrizia, Dumoulin, Mireille, Dobson, Christopher M., Fontana, Angelo

“…Human lysozyme variants form amyloid fibrils in individuals suffering from a familial non-neuropathic systemic amyloidosis. In vitro, wild-type human and hen…”
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Unique Features of a New Baeyer–Villiger Monooxygenase from a Halophilic Archaeon by Mattia Niero, Irene Righetto, Elisa Beneventi, Patrizia Polverino de Laureto, Marco Wilhelmus Fraaije, Francesco Filippini, Elisabetta Bergantino

“…Type I Baeyer−Villiger monooxygenases (BVMOs) are flavin-dependent monooxygenases that catalyze the oxidation of ketones to esters or lactones, a reaction…”
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Environmental Signals Act as a Driving Force for Metabolic and Defense Responses in the Antarctic Plant Colobanthus quitensis by Bertini, Laura, Proietti, Silvia, Fongaro, Benedetta, Holfeld, Aleš, Picotti, Paola, Falconieri, Gaia Salvatore, Bizzarri, Elisabetta, Capaldi, Gloria, Polverino de Laureto, Patrizia, Caruso, Carla

“…During evolution, plants have faced countless stresses of both biotic and abiotic nature developing very effective mechanisms able to perceive and counteract…”
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Changes in protein expression in two cholangiocarcinoma cell lines undergoing formation of multicellular tumor spheroids in vitro by Mischiati, Carlo, Ura, Blendi, Roncoroni, Leda, Elli, Luca, Cervellati, Carlo, Squerzanti, Monica, Conte, Dario, Doneda, Luisa, Polverino de Laureto, Patrizia, de Franceschi, Giorgia, Calza, Roberta, Barrero, Carlos A, Merali, Salim, Ferrari, Carlo, Bergamini, Carlo M, Agostinelli, Enzo

“…Epithelial-to-Mesenchymal Transition (EMT) is relevant in malignant growth and frequently correlates with worsening disease progression due to its implications…”
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