Search Results - "Poluektova, L. Y."

Amphiphilic Cationic Nanogels as Brain-Targeted Carriers for Activated Nucleoside Reverse Transcriptase Inhibitors by Warren, G., Makarov, E., Lu, Y., Senanayake, T., Rivera, K., Gorantla, S., Poluektova, L. Y., Vinogradov, S. V.

“…Progress in AIDS treatment shifted emphasis towards limiting adverse effects of antiviral drugs while improving the treatment of hard-to-reach viral…”
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Neuroprotective Activities of Sodium Valproate in a Murine Model of Human Immunodeficiency Virus-1 Encephalitis by Dou, Huanyu, Birusingh, Kevin, Faraci, Jill, Gorantla, Santhi, Poluektova, Larisa Y, Maggirwar, Sanjay B, Dewhurst, Stephen, Gelbard, Harris A, Gendelman, Howard E

“…Human immunodeficiency virus-1 (HIV-1) infection of the nervous system can result in neuroinflammatory events leading first to neuronal dysfunction then to…”
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Generation of Cytotoxic T Cells Against Virus-Infected Human Brain Macrophages in a Murine Model of HIV-1 Encephalitis by Poluektova, Larisa Y, Munn, David H, Persidsky, Yuri, Gendelman, Howard E

“…HIV-1 encephalitis (HIVE) and its associated dementia can occur in up to 20% of infected individuals, usually when productive viral replication in brain…”
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Protein kinase A inhibitors reverse histamine-mediated regulation of IL-5 secretion by Poluektova, Larisa Y., Khan, Manzoor M.

“…Histamine and IL-5 are important autacoid mediators involved in the etiology of allergic diseases. IL-5 is the main factor of eosinophilic reactions in…”
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Involvement of protein kinase A in histamine-mediated inhibition of IL-2 mRNA expression in mouse splenocytes by POLUEKTOVA, L. Y, HUGGLER, G. K, PATTERSON, E. B, KHAN, M. M

“…The release of histamine from mast cells and basophils during allergic reactions can regulate functions of T cells and may influence the nature of the immune…”
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OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis by Carlson, Kimberly A., Limoges, Jenae, Pohlman, Garrett D., Poluektova, Larisa Y., Langford, Dianne, Masliah, Eliezer, Ikezu, Tsuneya, Gendelman, Howard E.

“…OTK18 was isolated by mRNA differential display of human monocyte-derived macrophages (MDM) infected with human immunodeficiency virus type one (HIV-1)…”
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Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice by DASH, Prasanta K, GENDELMAN, Howard E, ROY, Upal, BALKUNDI, Shantanu, ALNOUTI, Yazen, MOSLEY, Rodney L, GELBARD, Harris A, MCMILLAN, Joellyn, GORANTLA, Santhi, POLUEKTOVA, Larisa Y

“…Long-acting nanoformulated antiretroviral therapy (nanoART) with improved pharmacokinetics, biodistribution and limited systemic toxicities will likely improve…”
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Protection from the toxicity of diisopropylfluorophosphate by adeno-associated virus expressing acetylcholinesterase by Li, Bin, Duysen, Ellen G., Poluektova, Larisa Y., Murrin, L. Charles, Lockridge, Oksana

“…Organophosphorus esters (OP) are highly toxic chemicals used as pesticides and nerve agents. Their acute toxicity is attributed to inhibition of…”
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A novel humanized mouse model for HIV-1 encephalitis by Poluektova, L Y, Sneller, H, Gebhard, C, Gendelman, HE, Gorantla, S

“…A novel rodent model was developed for studies of HIV-1 neuropathogenesis. Human hematopoietic stem cells derived from umbilical cord blood were used to…”
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Cisplatin-loaded core cross-linked micelles: comparative pharmacokinetics, antitumor activity, and toxicity in mice by Oberoi, Hardeep S, Nukolova, Natalia V, Laquer, Frederic C, Poluektova, Larisa Y, Huang, Jiangeng, Alnouti, Yazen, Yokohira, Masanao, Arnold, Lora L, Kabanov, Alexander V, Cohen, Samuel M, Bronich, Tatiana K

“…Polymer micelles with cross-linked ionic cores are shown here to improve the therapeutic performance of the platinum-containing anticancer compound cisplatin…”
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Neuroprotective Mechanisms of Lithium in Murine Human Immunodeficiency Virus-1 Encephalitis by Dou, Huanyu, Ellison, Brent, Bradley, Jennifer, Kasiyanov, Alexander, Poluektova, Larisa Y, Xiong, Huangui, Maggirwar, Sanjay, Dewhurst, Stephen, Gelbard, Harris A, Gendelman, Howard E

“…Lithium (Li) has garnered considerable interest as a neuroprotective drug for a broad range of nervous system disorders. Its neuroprotective activities occur…”
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Generation of Cytotoxic T Cells Against Virus-Infected Human Brain Macrophages in a Murine Model of HIV-1 Encephalitis by Poluektova, Larisa Y., Munn, David H., Persidsky, Yuri, Gendelman, Howard E.

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