Search Results - "Polster, Sean P."

In Reply: Surgical Performance Determines Functional Outcome Benefit in the Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation (MISTIE) Procedure by Polster, Sean P, Awad, Issam A

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Cerebral Cavernous Malformation Proteins in Barrier Maintenance and Regulation by Wei, Shu, Li, Ye, Polster, Sean P, Weber, Christopher R, Awad, Issam A, Shen, Le

“…Cerebral cavernous malformation (CCM) is a disease characterized by mulberry shaped clusters of dilated microvessels, primarily in the central nervous system…”
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Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma by Polster, Sean P., Sharma, Anukriti, Tanes, Ceylan, Tang, Alan T., Mericko, Patricia, Cao, Ying, Carrión-Penagos, Julián, Girard, Romuald, Koskimäki, Janne, Zhang, Dongdong, Stadnik, Agnieszka, Romanos, Sharbel G., Lyne, Seán B., Shenkar, Robert, Yan, Kimberly, Lee, Cornelia, Akers, Amy, Morrison, Leslie, Robinson, Myranda, Zafar, Atif, Bittinger, Kyle, Kim, Helen, Gilbert, Jack A., Kahn, Mark L., Shen, Le, Awad, Issam A.

“…Cavernous angiomas (CA) are common vascular anomalies causing brain hemorrhage. Based on mouse studies, roles of gram-negative bacteria and altered intestinal…”
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Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican by Hong, Courtney C, Tang, Alan T, Detter, Matthew R, Choi, Jaesung P, Wang, Rui, Yang, Xi, Guerrero, Andrea A, Wittig, Carl F, Hobson, Nicholas, Girard, Romuald, Lightle, Rhonda, Moore, Thomas, Shenkar, Robert, Polster, Sean P, Goddard, Lauren M, Ren, Aileen A, Leu, N Adrian, Sterling, Stephanie, Yang, Jisheng, Li, Li, Chen, Mei, Mericko-Ishizuka, Patricia, Dow, Lukas E, Watanabe, Hideto, Schwaninger, Markus, Min, Wang, Marchuk, Douglas A, Zheng, Xiangjian, Awad, Issam A, Kahn, Mark L

“…Cerebral cavernous malformations (CCMs) form following loss of the CCM protein complex in brain endothelial cells due to increased endothelial MEKK3 signaling…”
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Cavernous angiomas: deconstructing a neurosurgical disease by Awad, Issam A, Polster, Sean P

“…Cavernous angioma (CA) is also known as cavernoma, cavernous hemangioma, and cerebral cavernous malformation (CCM) (National Library of Medicine Medical…”
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Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations by Koskimäki, Janne, Zhang, Dongdong, Li, Yan, Saadat, Laleh, Moore, Thomas, Lightle, Rhonda, Polster, Sean P, Carrión-Penagos, Julián, Lyne, Seán B, Zeineddine, Hussein A, Shi, Changbin, Shenkar, Robert, Romanos, Sharbel, Avner, Kenneth, Srinath, Abhinav, Shen, Le, Detter, Matthew R, Snellings, Daniel, Cao, Ying, Lopez-Ramirez, Miguel A, Fonseca, Gregory, Tang, Alan T, Faber, Pieter, Andrade, Jorge, Ginsberg, Mark, Kahn, Mark L, Marchuk, Douglas A, Girard, Romuald, Awad, Issam A

“…Cerebral cavernous malformations (CCMs) are dilated capillaries causing epilepsy and stroke. Inheritance of a heterozygous mutation in CCM3/PDCD10 is…”
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Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes by Koskimäki, Janne, Girard, Romuald, Li, Yan, Saadat, Laleh, Zeineddine, Hussein A, Lightle, Rhonda, Moore, Thomas, Lyne, Seán, Avner, Kenneth, Shenkar, Robert, Cao, Ying, Shi, Changbin, Polster, Sean P, Zhang, Dongdong, Carrión-Penagos, Julián, Romanos, Sharbel, Fonseca, Gregory, Lopez-Ramirez, Miguel A, Chapman, Eric M, Popiel, Evelyn, Tang, Alan T, Akers, Amy, Faber, Pieter, Andrade, Jorge, Ginsberg, Mark, Derry, W Brent, Kahn, Mark L, Marchuk, Douglas A, Awad, Issam A

“…The purpose of this study was to determine important genes, functions, and networks contributing to the pathobiology of cerebral cavernous malformation (CCM)…”
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Sex and Age Dimorphism of Myocardial Gene Expression in Nonischemic Human Heart Failure by Fermin, David R, Barac, Ana, Lee, Sangjin, Polster, Sean P, Hannenhalli, Sridhar, Bergemann, Tracy L, Grindle, Suzanne, Dyke, David B, Pagani, Francis, Miller, Leslie W, Tan, Sarah, dos Remedios, Cris, Cappola, Thomas P, Margulies, Kenneth B, Hall, Jennifer L

“…Sex and Age Dimorphism of Myocardial Gene Expression in Nonischemic Human Heart Failure David R. Fermin, MD ; Ana Barac, MD ; Sangjin Lee, MD ; Sean P…”
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In Reply: Intracerebral Hemorrhage Volume Reduction and Timing of Intervention Versus Functional Benefit and Survival in the MISTIE III and STICH Trials by Polster, Sean P, Awad, Issam A

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A comparison of endoscopic endonasal versus open approaches for skull base chordoma: a comprehensive National Cancer Database analysis by Soffer, Justin M, Ulloa, Ruben, Chen, Sonja, Ziltzer, Ryan S, Patel, Vijay A, Polster, Sean P

“…The authors of this study aimed to investigate independent prognostic factors of survival with a particular focus on comparing the safety and efficacy of…”
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Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial by Polster, Sean P, Stadnik, Agnieszka, Akers, Amy L, Cao, Ying, Christoforidis, Gregory A, Fam, Maged D, Flemming, Kelly D, Girard, Romuald, Hobson, Nicholas, Koenig, James I, Koskimäki, Janne, Lane, Karen, Liao, James K, Lee, Cornelia, Lyne, Seán B, McBee, Nichol, Morrison, Leslie, Piedad, Kristina, Shenkar, Robert, Sorrentino, Matthew, Thompson, Richard E, Whitehead, Kevin J, Zeineddine, Hussein A, Hanley, Daniel F, Awad, Issam A

“…Abstract BACKGROUND More than a million Americans harbor a cerebral cavernous angioma (CA), and those who suffer a prior symptomatic hemorrhage have an…”
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Intracerebral Hemorrhage Volume Reduction and Timing of Intervention Versus Functional Benefit and Survival in the MISTIE III and STICH Trials by Polster, Sean P, Carrión-Penagos, Julián, Lyne, Seán B, Gregson, Barbara A, Cao, Ying, Thompson, Richard E, Stadnik, Agnieszka, Girard, Romuald, Money, Patricia Lynn, Lane, Karen, McBee, Nichol, Ziai, Wendy, Mould, W Andrew, Iqbal, Ahmed, Metcalfe, Stephen, Hao, Yi, Dodd, Robert, Carlson, Andrew P, Camarata, Paul J, Caron, Jean-Louis, Harrigan, Mark R, Zuccarello, Mario, Mendelow, A David, Hanley, Daniel F, Awad, Issam A

“…Abstract BACKGROUND The extent of intracerebral hemorrhage (ICH) removal conferred survival and functional benefits in the minimally invasive surgery with…”
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Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease by Shenkar, Robert, Peiper, Amy, Pardo, Heidy, Moore, Thomas, Lightle, Rhonda, Girard, Romuald, Hobson, Nicholas, Polster, Sean P, Koskimäki, Janne, Zhang, Dongdong, Lyne, Seán B, Cao, Ying, Chaudagar, Kiranj, Saadat, Laleh, Gallione, Carol, Pytel, Peter, Liao, James K, Marchuk, Douglas, Awad, Issam A

“…BACKGROUND AND PURPOSE—Previously, murine models Krit1Msh2 and Ccm2Trp53 showed a reduction or no effect on cerebral cavernous malformation (CCM) burden and…”
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Temporal Changes on Postgadolinium MR Vessel Wall Imaging Captures Enhancement Kinetics of Intracranial Atherosclerotic Plaques and Aneurysms by Patel, Abhinav, Abdalla, Ramez N, Allaw, Sammy, Cantrell, Donald R, Shaibani, Ali, Caprio, Frances, Hasan, David M, Alaraj, Ali, Polster, Sean P, Carroll, Timothy J, Ansari, Sameer A

“…Analysis of vessel wall contrast kinetics (ie, wash-in/washout) is a promising method for the diagnosis and risk-stratification of intracranial atherosclerotic…”
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The Time Burden of Office Visits in Contemporary Pituitary Care, 2016 to 2019 by Dimitroyannis, Rose C., Cyberski, Thomas F., Kondamuri, Neil S., Polster, Sean P., Das, Paramita, Horowitz, Peleg M., Roxbury, Christopher R.

“…Background The concept of “time toxicity” has emerged to address the impact of time spent in the healthcare system; however, little work has examined the…”
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Contemporary Management of Pediatric Invasive Fungal Rhinosinusitis by Zhou, Sheng, Yu, Alison, Frank, Ethan, Valencia-Sanchez, Bastien A., Chen, Sonja, Polster, Sean P., Patel, Vijay A.

“…Purpose of Review Pediatric invasive fungal sinusitis is a devasting disease that classically affects pediatric hematology/oncology patients. It necessitates…”
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Case Demonstrating the Nuances of Acute Cortical Venous Thrombosis Anticoagulation Guidelines by Polster, Sean P., Lyne, Seán B., Mansour, Ali

“…The American Stroke Association and the European Stroke Organization have established guidelines on cerebral venous thrombosis (CVT); however, questions remain…”
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Trial Readiness in Cavernous Angiomas With Symptomatic Hemorrhage (CASH) by Polster, Sean P, Cao, Ying, Carroll, Timothy, Flemming, Kelly, Girard, Romuald, Hanley, Daniel, Hobson, Nicholas, Kim, Helen, Koenig, James, Koskimäki, Janne, Lane, Karen, Majersik, Jennifer J, McBee, Nichol, Morrison, Leslie, Shenkar, Robert, Stadnik, Agnieszka, Thompson, Richard E, Zabramski, Joseph, Zeineddine, Hussein A, Awad, Issam A

“…Abstract BACKGROUND Brain cavernous angiomas with symptomatic hemorrhage (CASH) are uncommon but exact a heavy burden of neurological disability from recurrent…”
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Patients with cranial dural arteriovenous fistulas may benefit from expanded hypercoagulability and cancer screening by Polster, Sean P, Zeineddine, Hussein A, Baron, Joseph, Lee, Seon-Kyu, Awad, Issam A

“…Cranial dural arteriovenous fistulas (DAVFs) have been associated with dural sinus occlusion, and previous reports have suggested the association of…”
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Headache Diagnosis in Children and Adolescents by Patel, Vijay A., Liaw, Jeffrey, Saadi, Robert A., Isildak, Huseyin, Kalmar, Christopher L., Polster, Sean P.

“…Pediatric headache is a common medical complaint managed across multiple subspecialties with a myriad of unique factors (clinical presentation and disease…”
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