Search Results - "Polsinelli, Ivan"

Determination and Kinetic Characterization of a New Potential Inhibitor for AmsI Protein Tyrosine Phosphatase from the Apple Pathogen Erwinia amylovora by Albani, Simone, Polsinelli, Ivan, Mazzei, Luca, Musiani, Francesco, Benini, Stefano

“…is a Gram-negative bacterium, responsible for the fire blight disease in Rosaceae plants. Its virulence is correlated with the production of an…”
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The Structure of Sucrose-Soaked Levansucrase Crystals from Erwinia tasmaniensis reveals a Binding Pocket for Levanbiose by Polsinelli, Ivan, Caliandro, Rosanna, Demitri, Nicola, Benini, Stefano

“…Given its potential role in the synthesis of novel prebiotics and applications in the pharmaceutical industry, a strong interest has developed in the enzyme…”
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A genome-wide analysis of desferrioxamine mediated iron uptake in Erwinia spp. reveals genes exclusive of the Rosaceae infecting strains by Polsinelli, Ivan, Borruso, Luigimaria, Caliandro, Rosanna, Triboli, Luca, Esposito, Alfonso, Benini, Stefano

“…Erwinia amylovora is the etiological agent of fire blight, a devastating disease which is a global threat to commercial apple and pear production. The Erwinia…”
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Unravelling Novel SCN5A Mutations Linked to Brugada Syndrome: Functional, Structural, and Genetic Insights by Frosio, Anthony, Micaglio, Emanuele, Polsinelli, Ivan, Calamaio, Serena, Melgari, Dario, Prevostini, Rachele, Ghiroldi, Andrea, Binda, Anna, Carrera, Paola, Villa, Marco, Mastrocinque, Flavio, Presi, Silvia, Salerno, Raffaele, Boccellino, Antonio, Anastasia, Luigi, Ciconte, Giuseppe, Ricagno, Stefano, Pappone, Carlo, Rivolta, Ilaria

“…Brugada Syndrome (BrS) is a rare inherited cardiac arrhythmia causing potentially fatal ventricular tachycardia or fibrillation, mainly occurring during rest…”
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Determination and Kinetic Characterization of a New Potential Inhibitor for AmsI Protein Tyrosine Phosphatase from the Apple Pathogen IErwinia amylovora/I by Albani, Simone, Polsinelli, Ivan, Mazzei, Luca, Musiani, Francesco, Benini, Stefano

“…Erwinia amylovora is a Gram-negative bacterium, responsible for the fire blight disease in Rosaceae plants. Its virulence is correlated with the production of…”
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Erwinia tasmaniensis levansucrase shows enantiomer selection for (S)‐1,2,4‐butanetriol by Polsinelli, Ivan, Salomone-Stagni, Marco, Benini, Stefano

“…Levansucrases are biotechnologically interesting fructosyltransferases due to their potential use in the enzymatic or chemo‐enzymatic synthesis of glycosides…”
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The structural and functional characterization of Malus domestica double bond reductase MdDBR provides insights towards the identification of its substrates by Caliandro, Rosanna, Polsinelli, Ivan, Demitri, Nicola, Musiani, Francesco, Martens, Stefan, Benini, Stefano

“…In this study we describe the crystal structures of the apoform, the binary and the ternary complexes of a double bond reductase from Malus domestica L…”
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A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora by Salomone-Stagni, Marco, Bartho, Joseph D., Polsinelli, Ivan, Bellini, Dom, Walsh, Martin A., Demitri, Nicola, Benini, Stefano

“…[Display omitted] •Whole desferrioxamine E biosynthetic pathway revealed.•DfoJ: first structure of a group II PLP-dependent lysine decarboxylase.•DfoA: first…”
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Conservation of Erwinia amylovora pathogenicity-relevant genes among Erwinia genomes by Borruso, Luigimaria, Salomone-Stagni, Marco, Polsinelli, Ivan, Schmitt, Armin Otto, Benini, Stefano

“…The Erwinia genus comprises species that are plant pathogens, non-pathogen, epiphytes, and opportunistic human pathogens. Within the genus, Erwinia amylovora…”
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Comparison of the Levansucrase from the epiphyte Erwinia tasmaniensis vs its homologue from the phytopathogen Erwinia amylovora by Polsinelli, Ivan, Caliandro, Rosanna, Salomone-Stagni, Marco, Demitri, Nicola, Rejzek, Martin, Field, Robert A., Benini, Stefano

“…Erwinia tasmaniensis is an epiphytic bacterium related to the plant pathogen Erwinia amylovora, the etiological agent of fire blight. In this study the…”
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Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme by Kubiak, Xavier, Polsinelli, Ivan, Chavas, Leonard M. G., Fyfe, Cameron D., Guillot, Alain, Fradale, Laura, Brewee, Clémence, Grimaldi, Stéphane, Gerbaud, Guillaume, Thureau, Aurélien, Legrand, Pierre, Berteau, Olivier, Benjdia, Alhosna

“…d -Amino acid residues, found in countless peptides and natural products including ribosomally synthesized and post-translationally modified peptides (RiPPs),…”
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A new crystal form of human transthyretin obtained with a curcumin derived ligand by Polsinelli, Ivan, Nencetti, Susanna, Shepard, William, Ciccone, Lidia, Orlandini, Elisabetta, Stura, Enrico A.

“…Transthyretin (TTR), a 54kDa homotetrameric protein that transports thyroxine (T4), has been associated with clinical cases of TTR amyloidosis for its tendency…”
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Unravelling Novel ISCN5A/I Mutations Linked to Brugada Syndrome: Functional, Structural, and Genetic Insights by Frosio, Anthony, Micaglio, Emanuele, Polsinelli, Ivan, Calamaio, Serena, Melgari, Dario, Prevostini, Rachele, Ghiroldi, Andrea, Binda, Anna, Carrera, Paola, Villa, Marco, Mastrocinque, Flavio, Presi, Silvia, Salerno, Raffaele, Boccellino, Antonio, Anastasia, Luigi, Ciconte, Giuseppe, Ricagno, Stefano, Pappone, Carlo, Rivolta, Ilaria

“…Brugada Syndrome (BrS) is a rare inherited cardiac arrhythmia causing potentially fatal ventricular tachycardia or fibrillation, mainly occurring during rest…”
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Comparison of helical scan and standard rotation methods in single‐crystal X‐ray data collection strategies by Polsinelli, Ivan, Savko, Martin, Rouanet-Mehouas, Cecile, Ciccone, Lidia, Nencetti, Susanna, Orlandini, Elisabetta, Stura, Enrico A., Shepard, William

“…X‐ray radiation in macromolecular crystallography can chemically alter the biological material and deteriorate the integrity of the crystal lattice with…”
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