Search Results - "Polrot, Mélanie"

Successful Tumor Electrochemotherapy Using Sine Waves by Garcia-Sanchez, Tomas, Mercadal, Borja, Polrot, Melanie, Muscat, Adeline, Sarnago, Hector, Lucia, Oscar, Mir, Lluis M.

“…Objective: The purpose of this work is to assess the ability of sine waves to perform electrochemotherapy (ECT) and to study the dependence of the frequency of…”
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Tumour spheres with inverted polarity drive the formation of peritoneal metastases in patients with hypermethylated colorectal carcinomas by Zajac, Olivier, Raingeaud, Joel, Libanje, Fotine, Lefebvre, Celine, Sabino, Dora, Martins, Isabelle, Roy, Pétronille, Benatar, Clara, Canet-Jourdan, Charlotte, Azorin, Paula, Polrot, Mélanie, Gonin, Patrick, Benbarche, Salima, Souquere, Sylvie, Pierron, Gerard, Nowak, Damien, Bigot, Ludovic, Ducreux, Michel, Malka, David, Lobry, Camille, Scoazec, Jean-Yves, Eveno, Clarisse, Pocard, Marc, Perfettini, Jean-Luc, Elias, Dominique, Dartigues, Peggy, Goéré, Diane, Jaulin, Fanny

“…Metastases account for 90% of cancer-related deaths; thus, it is vital to understand the biology of tumour dissemination. Here, we collected and monitored >50…”
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MT2A is an early predictive biomarker of response to chemotherapy and a potential therapeutic target in osteosarcoma by Mangelinck, Adèle, da Costa, Maria Eugénia Marques, Stefanovska, Bojana, Bawa, Olivia, Polrot, Mélanie, Gaspar, Nathalie, Fromigué, Olivia

“…Osteosarcoma is the most prevalent primary bone malignancy in children and young adults. Resistance to chemotherapy remains a key challenge for effective…”
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Patient-derived organoids identify an apico-basolateral polarity switch associated with survival in colorectal cancer by Canet-Jourdan, Charlotte, Pagès, Diane-Laure, Nguyen-Vigouroux, Clémence, Cartry, Jérôme, Zajac, Olivier, Desterke, Christophe, Lopez, Jean-Baptiste, Gutierrez-Mateyron, Emie, Signolle, Nicolas, Adam, Julien, Raingeaud, Joel, Polrot, Mélanie, Gonin, Patrick, Mathieu, Jacques R R, Souquere, Sylvie, Pierron, Gerard, Gelli, Maximiliano, Dartigues, Peggy, Ducreux, Michel, Barresi, Valeria, Jaulin, Fanny

“…The metastatic progression of cancer remains a major issue in patient treatment. Yet, the molecular and cellular mechanisms underlying this process remains…”
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Fas Ligand Deficiency Impairs Tumor Immunity by Promoting an Accumulation of Monocytic Myeloid-Derived Suppressor Cells by Peyvandi, Sanam, Buart, Stéphanie, Samah, Boubekeur, Vétizou, Marie, Zhang, Yanyan, Durrieu, Ludovic, Polrot, Mélanie, Chouaib, Salem, Benihoud, Karim, Louache, Fawzia, Karray, Saoussen

“…The Fas receptor ligand FasL regulates immune cell levels by inducing apoptosis of Fas receptor-positive cells. Here, we studied the impact of host FasL on…”
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Towards a clinical application of freeze-dried squalene-based nanomedicines by Rouquette, Marie, Ser-Le Roux, Karine, Polrot, Mélanie, Bourgaux, Claudie, Michel, Jean-Philippe, Testard, Fabienne, Gobeaux, Frédéric, Lepetre-Mouelhi, Sinda

“…Squalene-adenosine (SQAd) nanoparticles (NPs) were found to display promising pharmacological activity similar to many other nanomedicines, but their long-term…”
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Pickering emulsions with ethiodized oil and nanoparticles for slow release of intratumoral anti-CTLA4 immune checkpoint antibodies by Tselikas, Lambros, de Baere, Thierry, Isoardo, Thomas, Susini, Sandrine, Ser-Le Roux, Karine, Polrot, Mélanie, Adam, Julien, Rouanne, Mathieu, Zitvogel, Laurence, Moine, Laurence, Deschamps, Fréderic, Marabelle, Aurélien

“…BackgroundIntratumorous immunotherapy for cancer is currently thriving. The aim of such local strategy is to improve the therapeutic index of these treatments,…”
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Assessment of quantitative perfusion parameters by dynamic contrast-enhanced sonography using a deconvolution method: an in vitro and in vivo study by Gauthier, Marianne, Tabarout, Farid, Leguerney, Ingrid, Polrot, Mélanie, Pitre, Stéphanie, Peronneau, Pierre, Lassau, Nathalie

“…The purpose of this study was to investigate the impact of the arterial input on perfusion parameters measured using dynamic contrast-enhanced sonography…”
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Suppressor of cytokine signaling 1 modulates invasion and metastatic potential of colorectal cancer cells by David, Muriel, Naudin, Cécile, Letourneur, Martine, Polrot, Mélanie, Renoir, Jack-Michel, Lazar, Vladimir, Dessen, Philippe, Roche, Serge, Bertoglio, Jacques, Pierre, Josiane

“…Suppressor of cytokine signaling (SOCS) 1 is an inducible negative regulator of cytokine signaling but its role in human cancer is not completely established…”
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Cetuximab increases concentrations of irinotecan and of its active metabolite SN-38 in plasma and tumour of human colorectal carcinoma-bearing mice by Chu, Céline, Abbara, Chadi, Tandia, Mahamadou, Polrot, Mélanie, Gonin, Patrick, Farinotti, Robert, Bonhomme-Faivre, Laurence

“…In a previous study, we showed that cetuximab, a monoclonal antibody directed towards epidermal growth factor receptor, could inhibit P‐glycoprotein (P‐gp), an…”
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Therapeutic efficiency of everolimus and lapatinib in xenograft model of human colorectal carcinoma with KRAS mutation by Chu, Céline, Noël-Hudson, Marie-Sophie, Boige, Valérie, Goéré, Diane, Marion, Sylvie, Polrot, Mélanie, Bigot, Ludovic, Gonin, Patrick, Farinotti, Robert, Bonhomme-Faivre, Laurence

“…KRAS mutation is a negative predictive prognostic factor during metastatic colorectal cancer treatment with antiepidermal growth factor receptor antibodies…”
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Impact of the arterial input function on microvascularization parameter measurements using dynamic contrast-enhanced ultrasonography by Gauthier, Marianne, Pitre-Champagnat, Stéphanie, Tabarout, Farid, Leguerney, Ingrid, Polrot, Mélanie, Lassau, Nathalie

“…AIM: To evaluate the sources of variation influencing the microvascularization parameters measured by dynamic contrast-enhanced ultrasonography (DCE-US)…”
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DiPRO1 distinctly reprograms muscle and mesenchymal cancer cells by Rich, Jeremy, Bennaroch, Melanie, Notel, Laura, Patalakh, Polina, Alberola, Julien, Issa, Fayez, Opolon, Paule, Bawa, Olivia, Rondof, Windy, Marchais, Antonin, Dessen, Philippe, Meurice, Guillaume, Le-Gall, Morgane, Polrot, Melanie, Ser-Le Roux, Karine, Mamchaoui, Kamel, Droin, Nathalie, Raslova, Hana, Maire, Pascal, Geoerger, Birgit, Pirozhkova, Iryna

“…We have recently identified the uncharacterized ZNF555 protein as a component of a productive complex involved in the morbid function of the 4qA locus in…”
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Towards a clinical application of freeze-dried squalene-based nanomedicines by Rouquette, Marie, Ser-Le Roux, Karine, Polrot, Mélanie, Bourgaux, Claudie, Michel, Jean-Philippe, Testard, Fabienne, Gobeaux, Frédéric, Lepetre-Mouelhi, Sinda

“…Squalene-adenosine (SQAd) nanoparticles (NPs) were found to display promising pharmacological activity similar to many other nanomedicines, but their long-term…”
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AG-221, an Oral, Selective, First-in-Class, Potent IDH2-R140Q Mutant Inhibitor, Induces Differentiation in a Xenotransplant Model by Quivoron, Cyril, David, Muriel, Straley, Kim, Travins, Jeremy, Kim, Hyeryun, Chen, Yue, Zhu, Dongwei, Saada, Véronique, Bawa, Olivia, Opolon, Paule, Polrot, Mélanie, Micol, Jean-Baptiste, Willekens, Christophe, Bernard, Olivier, Yang, Hua, Agresta, Sam, de Botton, Stéphane, Yen, Katharine, Penard-Lacronique, Virginie

“…Somatic point mutations in the active site of IDH (isocitrate dehydrogenase) 1 and IDH2 genes are observed in acute myeloid leukemia (AML). These mutations…”
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Abstract 2665: NBTXR3 hafnium oxide nanoparticle activated by ionizing radiation demonstrates marked radio-enhancement and antitumor effect via high energy deposit in human soft tissue sarcoma by Laurence, Maggiorella, Darmon, Audrey, Vivet, Sonia, Polrot, Mélanie, Zhang, Ping, Deutsch, Eric, Bourhis, Jean, Pottier, Agnès, Borghi, Elsa, Levy, Laurent

“…Local and systemic control of Soft Tissue Sarcoma (STS) remains a clinical challenge. Radiation therapy is part of the standard of care of STS. The narrowness…”
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Assessment of Quantitative Perfusion Parameters by Dynamic Contrast‐Enhanced Sonography Using a Deconvolution Method by Gauthier, Marianne, Tabarout, Farid, Leguerney, Ingrid, Polrot, Mélanie, Pitre, Stéphanie, Peronneau, Pierre, Lassau, Nathalie

“…Objectives The purpose of this study was to investigate the impact of the arterial input on perfusion parameters measured using dynamic contrast‐enhanced…”
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