Search Results - "Pologe, Laura"

Safety, pharmacokinetics, and immunogenicity of a co-formulated cocktail of three human monoclonal antibodies targeting Ebola virus glycoprotein in healthy adults: a randomised, first-in-human phase 1 study by Sivapalasingam, Sumathi, Kamal, Mohamed, Slim, Rabih, Hosain, Romana, Shao, Weiping, Stoltz, Randall, Yen, Joseph, Pologe, Laura G, Cao, Yuan, Partridge, Michael, Sumner, Giane, Lipsich, Leah

“…REGN3470-3471-3479 is a co-formulated cocktail of three human monoclonal antibodies targeting three non-overlapping epitopes on Ebola virus. We investigated…”
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A chromosomal rearrangement in a P. falciparum histidine-rich protein gene is associated with the knobless phenotype by Pologe, Laura G, Ravetch, Jeffrey V

“…The significant morbidity and mortality associated with Plasmodium falciparum malaria results, in part, from the sequestration of parasitized erythrocytes in…”
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Large deletions result from breakage and healing of P. falciparum chromosomes by Pologe, L G, Ravetch, J V

“…The human malaria parasite P. falciparum exhibits extensive strain-dependent chromosomal polymorphisms that have been implicated in the generation of antigenic…”
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Aberrant transcription and the failure of Plasmodium falciparum to differentiate into gametocytes by Pologe, L G

“…In the human malaria parasite, Plasmodium falciparum, a DNA rearrangement is associated with erroneous transcription of the early gametocyte antigen gene,…”
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Structural features of Plasmodium cytochrome b that may underlie susceptibility to 8-aminoquinolines and hydroxynaphthoquinones by Vaidya, A B, Lashgari, M S, Pologe, L G, Morrisey, J

“…Appropriate functioning of mitochondria is critical for survival and growth of erythrocytic stages of malarial parasites, making it an attractive target for…”
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Primary Structure and Subcellular Localization of the Knob-Associated Histidine-Rich Protein of Plasmodium falciparum by Pologe, Laura G., Pavlovec, Amalia, Shio, Helen, Ravetch, Jeffrey V.

“…Plasmodium falciparum-infected erythrocytes bind to venular endothelial cells by means of electron-dense deformations (knobs) on the parasitized erythrocyte…”
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Pfs2400 can mediate antibody-dependent malaria transmission inhibition and may be the Plasmodium falciparum 11.1 gene product by ZHENG FENG, HOFFMANN, R. N, NUSSENZWEIG, R. S, TSUJI, M, FUJIOKA, H, AIKAWA, M, LENSEN, T. H. W, PONNUDURAI, T, POLOGE, L. G

“…Monoclonal antibodies (mAb) have been raised against Plasmodium falciparum gametocyte stage protein extracts, in an effort to identify novel parasite antigens…”
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A and T homopolymeric stretches mediate a DNA inversion in Plasmodium falciparum which results in loss of gene expression by POLOGE, L. G, DE BRUIN, D, RAVETCH, J. V

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Knob-associated histidine-rich protein gene by POLOGE, LAURA G., RAVETCH, JEFFREY V

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Leukotriene C Promotes Prostacyclin Synthesis by Human Endothelial Cells by Cramer, Eva B., Pologe, Laura, Pawlowski, Nicholas A., Cohn, Zanvil A., Scott, William A.

“…Cultured endothelial cells from human umbilical vein were labeled with [3H]arachidonic acid for 16 hr. The radiolabel was localized primarily in phospholipids…”
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A and T Homopolymeric Stretches Mediate a DNA Inversion in Plasmodium falciparum Which Results in Loss of Gene Expression by Pologe, Laura G., de Bruin, Derik, Ravetch, Jeffrey V.

“…Ring-infected erythrocyte surface antigen-negative isolates of Plasmodium falciparum demonstrate a complex DNA rearrangement with inversion of 5′ coding…”
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Knob-associated histidine-rich protein gene by SHARMA, YAGYA D

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Stimulation of human endothelial cell prostacyclin synthesis by select leukotrienes by POLOGE, L. G, CRAMER, E. V, PAWLOWSKI, N. A, ABRAHAM, E, COHN, Z. A, SCOTT, W. A

“…Cultured endothelial cells from human umbilical cord labeled with [3H]20:4 release radiolabel when exposed to leukotrienes C or D (LTC or LTD). The major…”
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Nature of the riboflavin interaction with the immunoglobulin IgGGAR: analogue binding studies by Pologe, L G, Goyal, A, Greer, J

“…The human immunoglobulin IgGGAR has been shown to bind riboflavin both in vivo and in vitro with a high binding constant [Farhangi & Osserman (1976), New Engl…”
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