Search Results - "Polmar, S H"

Safety, pharmacokinetics and biological activity of enlimomab (anti-ICAM-1 antibody): an open-label, dose escalation study in patients hospitalized for acute stroke by Schneider, D, Berrouschot, J, Brandt, T, Hacke, W, Ferbert, A, Norris, S H, Polmar, S H, Schäfer, E

“…To obtain information on the safety, pharmacokinetics and biological activity of enlimomab (anti-ICAM-1 antibody) in stroke patients. An open, uncontrolled,…”
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Adenosine deaminase deficiency with late onset of recurrent infections: response to treatment with polyethylene glycol-modified adenosine deaminase by Levy, Y, Hershfield, M S, Fernandez-Mejia, C, Polmar, S H, Scudiery, D, Berger, M, Sorensen, R U

“…We report a 5-year-old girl with adenosine deaminase (ADA) deficiency who was asymptomatic during the first years of life. At 3 years of age, she developed…”
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Deoxyadenosine Triphosphate as a Potentially Toxic Metabolite in Adenosine Deaminase Deficiency by Cohen, Amos, Hirschhorn, Rochelle, Horowitz, Sheldon D., Rubinstein, Arieh, Polmar, Stephen H., Hong, Richard, Martin, David W.

“…The inherited deficiency of adenosine deaminase (adenosine aminohydrolase; EC 3.5.4.4) activity in humans is associated with an immunodeficiency. Some of the…”
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Spectrum of IgG2 subclass deficiency in children with recurrent infections: prospective study by Shackelford, P G, Polmar, S H, Mayus, J L, Johnson, W L, Corry, J M, Nahm, M H

“…Serum immunoglobulins and IgG subclasses were measured in 30 children with recurrent infections. Seven patients had low IgG2 concentrations (less than 3SD…”
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Cytotoxic factors secreted by cells infected by human immunodeficiency virus type I by Ratner, L, Polmar, S H, Paul, N, Ruddle, N

“…Conditioned media from human immunodeficiency virus type I (HIV-1) infected cells were tested for cytotoxic cell-derived factors. The assay used a murine…”
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Long-term immunological reconstitution by peripheral blood leucocytes in severe combined immune deficiency disease: implications for the role of mature lymphocytes in histocompatible bone marrow transplantation by POLMAR, S. H, SCHACTER, B. Z, SORENSEN, R. U

“…A 7 month old girl with severe combined immunodeficiency disease (SCID) received a single transfusion of peripheral blood leucocytes from her histocompatible…”
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Efficacy and safety of high-dose intravenous immune globulin therapy for antibody deficiency syndromes by Sorensen, R U, Polmar, S H

“…Ten patients with antibody deficiency syndromes were admitted to a treatment protocol in which the dose of intravenous immune serum globulin was increased from…”
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Lymphocyte dysfunction in cartilage-hair hypoplasia: evidence for an intrinsic defect in cellular proliferation by Pierce, GF, Polmar, SH

“…Individuals with cartilage-hair hypoplasia (CHH), an autosomal recessive form of short-limbed dwarfism, have markedly reduced lymphocyte proliferative…”
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Lymphocyte dysfunction in cartilage hair hypoplasia. II. Evidence for a cell cycle specific defect in T cell growth by Pierce, G F, Polmar, S H

“…Defects of in vitro B and T lymphocyte function and impaired delayed type hypersensitivity reactions, as well as an increased risk of lethal viral infections…”
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Defective cellular immunity to gram-negative bacteria in cystic fibrosis patients by Sorensen, R U, Stern, R C, Chase, P, Polmar, S H

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Cellular immunity to bacteria: impairment of in vitro lymphocyte responses to Pseudomonas aeruginosa in cystic fibrosis patients by Sorensen, R U, Stern, R C, Polmar, S H

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Pharmacological modification of immunoregulatory T lymphocytes . II. Modulation of T lymphocyte cell surface characteristics by Birch, R E, Rosenthal, A K, Polmar, S H

“…Human peripheral blood lymphocytes were fractionated into non-T lymphocyte, T lymphocyte, theophylline resistant (TR) and theophylline sensitive (Ts) T…”
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Impaired immunoregulation in systemic lupus erythematosus: defective adenosine-induced suppressor T lymphocyte generation by Kammer, GM, Birch, RE, Polmar, SH

“…It is currently unclear whether the suppressor cell dysfunction observed during active systemic lupus erythematosus (SLE) reflects a primary T cell disorder or…”
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Use of intravenous immune globulin in pregnant women with common variable hypogammaglobulinemia by Sorensen, R U, Tomford, J W, Gyves, M T, Judge, N E, Polmar, S H

“…Two patients with common variable hypogammaglobulinemia were treated with immune serum globulin during pregnancy. An intravenous immune serum globulin…”
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Staphylococcus aureus Cowan I-induced immunoglobulin production in human cord blood lymphocytes by Ruuskanen, O, Pittard, WB, 3d, Miller, K, Pierce, G, Sorensen, RU, Polmar, SH

“…Human cord blood mononuclear cells (MNC) were stimulated with antibiotic killed Staphylococcus aureus Cowan I bacteria (S. aureus) or pokeweed mitogen (PWM)…”
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A hereditary immunodeficiency characterized by CD8 T lymphocyte deficiency and impaired lymphocyte activation by MONAFO, W. J., POLMAR, S. H., NEUDORF, S., MATHER, A., FILIPOVICH, A. H.

“…SUMMARY An unusual form of severe combined immunodeficiency in children from two different families was associated with absence of CD8+ T lymphocytes and…”
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Impaired culture generated cytotoxicity with preservation of spontaneous natural killer-cell activity in cartilage-hair hypoplasia by Pierce, G F, Brovall, C, Schacter, B Z, Polmar, S H

“…Recent studies of cartilage-hair hypoplasia (CHH), a form of short-limbed dwarfism, have shown that all affected individuals have a cellular proliferation…”
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The metabolism of IgE in patients with immunodeficiency states and neoplastic conditions by Iio, A, Strober, W, Broder, S, Polmar, S H

“…Serum IgE concentrations were determined and IgE turnover studies were performed in control individuals as well as in patients with several disease states…”
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The role of the immunologist in sinus disease by Polmar, S H

“…The clinical immunologist is playing an increasingly important role in the evaluation and management of sinus disease. Although most patients with sinus…”
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Use of anti-ICAM-1 therapy in ischemic stroke: Results of the Enlimomab Acute Stroke Trial

“…There has been recent interest in the possible role of reperfusion-induced inflammation with neuronal injury after stroke. Enlimomab, a murine intercellular…”
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