Search Results - "Polloni, Lorena"

Action of copper(II) complex with β-diketone and 1,10-phenanthroline (CBP-01) on sarcoma cells and biological effects under cell death by Polloni, Lorena, Seni Silva, Ana Carolina de, Teixeira, Samuel Cota, Azevedo, Fernanda Van Petten de Vasconcelos, Zóia, Mariana Alves Pereira, da Silva, Marcelo Santos, Lima, Paula Marynella Alves Pereira, Correia, Lucas Ian Veloso, do Couto Almeida, Janaina, da Silva, Claudio Vieira, Rodrigues Ávila, Veridiana de Melo, Goulart, Luiz Ricardo Filho, Morelli, Sandra, Guerra, Wendell, Oliveira Júnior, Robson José de

“…[Display omitted] •The copper(II) complex (CBP-01) showed low cytotoxicity (IC50 = 26.4 μM) to murine myoblast (C2C12), a non-tumorigenic cell line.•CBP-01…”
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Cu(bta)(1,10-phen)ClO4 copper complex modulates the carcinogenicity of carboplatin in somatic cells of Drosophila melanogaster by Lima, Paula Marynella Alves Pereira, Orsonlin, Priscila Capelari, Machado, Nayane Moreira, Oliveira, Rosiane Gomes Silva, Polloni, Lorena, Cruz, Raquel Pereira, Almeida, Janaína do Couto, Oliveira Júnior, Robson José de, Guerra, Wendell, Araújo, Thaise Gonçalves

“…Chemotherapy stands out as the main systemic treatment strategy against cancer and still faces problems related to multidrug resistance and severe side…”
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Soybean genotypes selection with resistance to White Mold and agronomic performance from moderately resistant parents by Polloni-Barros, Lorraine Cristina, Hamawaki, Osvaldo Toshiyuki, Polloni, Lorena, Barros, Heber Leão Silva, Morais, Tâmara Prado de, Hamawaki, Raphael Lemes, Hamawaki, Cristiane Divina Lemes, Juliatti, Fernando Cezar, Nogueira, Ana Paula Oliveira

“…White Mold (WM) is a yield–limiting disease found in soybean. However, up to now no cultivars have been genetically resistant to this disease. Given this…”
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A New Approach to Inhibiting Triple-Negative Breast Cancer: In Vitro, Ex Vivo and In Vivo Antiangiogenic Effect of BthTx-II, a PLA2-Asp-49 from Bothrops jararacussu Venom by Van Petten de Vasconcelos Azevedo, Fernanda, Lopes, Daiana Silva, Zóia, Mariana Alves Pereira, Correia, Lucas Ian Veloso, Saito, Natieli, Fonseca, Belchiolina Beatriz, Polloni, Lorena, Teixeira, Samuel Cota, Goulart, Luiz Ricardo, de Melo Rodrigues Ávila, Veridiana

“…Phospholipases A2 (PLA2) represent a superfamily of enzymes widely distributed in living organisms, with a broad spectrum of pharmacological activities and…”
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Shedding Lights on Crude Venom from Solitary Foraging Predatory Ant Ectatomma opaciventre : Initial Toxinological Investigation by Correia, Lucas Ian Veloso, Azevedo, Fernanda Van Petten de Vasconcelos, Amorim, Fernanda Gobbi, Cirilo Gimenes, Sarah Natalie, Polloni, Lorena, Zoia, Mariana Alves Pereira, Costa, Mônica Soares, Rodrigues, Jéssica Peixoto, Yoneyama, Kelly A Geraldo, Santos, Jean Carlos, Arantes, Eliane Candiani, Rodrigues, Veridiana de Melo, Goulart, Luiz Ricardo, Rodrigues, Renata Santos

“…Some species of primitive predatory ants, despite living in a colony, exercise their hunting collection strategy individually; their venom is painful,…”
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BjussuLAAO-II, an l-amino acid oxidase from Bothrops jararacussu snake venom, impairs Toxoplasma gondii infection in human trophoblast cells and villous explants from the third trimester of pregnancy by de Melo Fernandes, Thales Alves, Teixeira, Samuel Cota, Costa, Tássia Rafaela, Rosini, Alessandra Monteiro, de Souza, Guilherme, Polloni, Lorena, Barbosa, Bellisa de Freitas, Silva, Marcelo José Barbosa, Ferro, Eloisa Amália Vieira, Ávila, Veridiana de Melo Rodrigues

“…One-third of the world's population is estimated to be affected by toxoplasmosis. Pregnancy-related Toxoplasma gondii infection can cause vertical…”
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Oxidative stress induced by Pollonein-LAAO, a new L-amino acid oxidase from Bothrops moojeni venom, prompts prostate tumor spheroid cell death and impairs the cellular invasion process in vitro by Polloni, Lorena, Costa, Tássia Rafaella, Morais, Lorena Pinheiro, Borges, Bruna Cristina, Teixeira, Samuel Cota, de Melo Fernandes, Thales Alves, Correia, Lucas Ian Veloso, Bastos, Luciana Machado, Amorim, Fernanda Gobbi, Quinton, Loïc, Soares, Andreimar Martins, Silva, Marcelo José Barbosa, Ferro, Eloisa Amália Vieira, Lopes, Daiana Silva, de Melo Rodrigues Ávila, Veridiana

“…Cancer cells produce abnormal levels of reactive oxygen species (ROS) that contribute to promote their malignant phenotype. In this framework, we hypothesized…”
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PLA2-MjTX-II from Bothrops moojeni snake venom exhibits antimetastatic and antiangiogenic effects on human lung cancer cells by Santos, Luísa Carregosa, Oliveira, Vinícius Queiroz, Teixeira, Samuel Cota, Correia, Thiago Macedo Lopes, Andrade, Leonardo Oliveira Silva Bastos, Polloni, Lorena, Marques, Lucas Miranda, Clissa, Patrícia Bianca, Baldo, Cristiani, Ferro, Eloisa Amália Vieira, Gusmão, Amélia Cristina Mendes de Magalhães, Silva, Marcelo José Barbosa, Sanabani, Sabri Saeed, Ávila, Veridiana de Melo Rodrigues, Lopes, Daiana Silva

“…Phospholipases A2 (PLA2s) from snake venom possess antitumor and antiangiogenic properties. In this study, we evaluated the antimetastatic and antiangiogenic…”
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Bothrops snake venom L-amino acid oxidases impair biofilm formation of clinically relevant bacteria by Alves de Melo Fernandes, Thales, Rafaella Costa, Tássia, de Paula Menezes, Ralciane, Arantes de Souza, Meliza, Gomes Martins, Carlos Henrique, Junior, Nilson Nicolau, Gobbi Amorim, Fernanda, Quinton, Loïc, Polloni, Lorena, Teixeira, Samuel Cota, Amália Vieira Ferro, Eloisa, Soares, Andreimar Martins, de Melo Rodrigues Ávila, Veridiana

“…The present work addressed the abilities of two L-amino acid oxidases isolated from Bothrops moojeni (BmooLAAO-I) and Bothrops jararacussu (BjussuLAAO-II)…”
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Biochemical characterization and assessment of leishmanicidal effects of a new L-amino acid oxidase from Crotalus durissus collilineatus snake venom (CollinLA AO-I) by de Freitas, Vitor, Costa, Tássia Rafaella, Nogueira, Amanda Rodrigues, Polloni, Lorena, Alves de Melo Fernandes, Thales, Correia, Lucas Ian Veloso, Borges, Bruna Cristina, Teixeira, Samuel Cota, Silva, Marcelo José Barbosa, Amorim, Fernanda Gobbi, Quinton, Loïc, Saraiva, André Lopes, Espindola, Foued Salmen, Iwai, Leo Kei, Rodrigues, Renata Santos, Yoneyama, Kelly Aparecida Geraldo, de Melo Rodrigues Ávila, Veridiana

“…This study reports the isolation of CollinLAAO-I, a new L-amino acid oxidase from Crotalus durissus collilineatus snake venom, its biochemical characterization…”
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In vitro and in vivo antitumoral activity of a ternary copper (II) complex by Lopes, Jeyson Césary, Botelho, Françoise Vasconcelos, Barbosa Silva, Marcelo José, Silva, Suélen Fernandes, Polloni, Lorena, Alves Machado, Pedro Henrique, Rodrigues de Souza, Tiago, Goulart, Luiz Ricardo, Silva Caldeira, Priscila Pereira, Pereira Maia, Elene Cristina, Morelli, Sandra, de Oliveira-Júnior, Robson J.

“…Recently, a high number of copper derivatives has been evaluated as DNA-targeting metallodrugs, due to the lower toxicity and its potential to cleave DNA…”
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Antiangiogenic effects of phospholipase A2 Lys49 BnSP-7 from Bothrops pauloensis snake venom on endothelial cells: An in vitro and ex vivo approach by Polloni, Lorena, Azevedo, Fernanda Van Petten Vasconcelos, Teixeira, Samuel Cota, Moura, Eloá, Costa, Tassia Rafaela, Gimenes, Sarah Natalie Cirilo, Correia, Lucas Ian Veloso, Freitas, Vitor, Yoneyama, Kelly Aparecida Geraldo, Rodrigues, Renata Santos, Lopes, Daiana Silva, Rodrigues, Veridiana de Melo

“…Antiangiogenic strategies are promising tools for cancer treatment and several other disorders. In this sense, phospholipases A2 (PLA2s) from snake venom have…”
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Crystal structure, anti-Trypanosoma cruzi and cytotoxic activities of Cu(II) complexes bearing β-diketone and α-diimine ligands by Paixão, Drielly A., de Oliveira, Barbara C.A., Almeida, Janaina do Couto, Sousa, Luana M., Lopes, Carla D., Carneiro, Zumira A., Tezuka, Daiane Y., Clavijo, Juan Carlos T., Ellena, Javier, Polloni, Lorena, Machado, Pedro H.A., de Albuquerque, Sérgio, de Oliveira Júnior, Robson J., Guilardi, Silvana, Guerra, Wendell

“…[Display omitted] •Three novel Cu(II) complexes containing β-diketone were prepared.•The X-ray structural analysis was performed.•A Cu(II) complex was active…”
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DNA interactions, antitubercular and cytotoxic activity of heteroleptic CuII complexes containing 1,10-phenanthroline by Almeida, Janaína do Couto, Silva, Raphael T.C., Zanetti, Renan D., Moreira, Mariete B., Portes, Marcelo C., Polloni, Lorena, de Vasconcelos Azevedo, Fernanda V.P., Von Poelhsitz, Gustavo, Pivatto, Marcos, Netto, Adelino V.G., Ávila, Veridiana de Melo R., Manieri, Karyn F., Pavan, Fernando R., Da Costa Ferreira, Ana M., Guerra, Wendell

“…•Four heteroleptic CuII complexes with 1,10-phenanthroline were prepared.•Such complexes were more cytotoxic than corresponding free ligands and…”
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Genotoxic effects of BnSP-6, a Lys-49 phospholipase A 2 (PLA 2 ) homologue from Bothrops pauloensis snake venom, on MDA-MB-231 breast cancer cells by Silva, Makswell Almeida, Lopes, Daiana Silva, Teixeira, Samuel Cota, Gimenes, Sarah Natalie Cirilo, Azevedo, Fernanda Van Petten Vasconcelos, Polloni, Lorena, Borges, Bruna Cristina, da Silva, Marcelo Santos, Barbosa, Marcelo José, Oliveira Júnior, Robson José de, Elias, Maria Carolina, da Silva, Claudio Vieira, Yoneyama, Kelly Aparecida Geraldo, Rodrigues, Veridiana de Melo, Rodrigues, Renata Santos

“…Herein we evaluated the genotoxic effects of BnSP-6, a Lys-49 phospholipase A (PLA ) from Bothrops pauloensis, on breast cancer cells. BnSP-6 was able to…”
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PLA 2 -MjTX-II from Bothrops moojeni snake venom exhibits antimetastatic and antiangiogenic effects on human lung cancer cells by Santos, Luísa Carregosa, Oliveira, Vinícius Queiroz, Teixeira, Samuel Cota, Correia, Thiago Macedo Lopes, Andrade, Leonardo Oliveira Silva Bastos, Polloni, Lorena, Marques, Lucas Miranda, Clissa, Patrícia Bianca, Baldo, Cristiani, Ferro, Eloisa Amália Vieira, Gusmão, Amélia Cristina Mendes de Magalhães, Silva, Marcelo José Barbosa, Sanabani, Sabri Saeed, Ávila, Veridiana de Melo Rodrigues, Lopes, Daiana Silva

“…Phospholipases A (PLA s) from snake venom possess antitumor and antiangiogenic properties. In this study, we evaluated the antimetastatic and antiangiogenic…”
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A New Approach to Inhibiting Triple-Negative Breast Cancer: In Vitro, Ex Vivo and In Vivo Antiangiogenic Effect of BthTx-II, a PLA 2 -Asp-49 from Bothrops jararacussu Venom by Van Petten de Vasconcelos Azevedo, Fernanda, Lopes, Daiana Silva, Zóia, Mariana Alves Pereira, Correia, Lucas Ian Veloso, Saito, Natieli, Fonseca, Belchiolina Beatriz, Polloni, Lorena, Teixeira, Samuel Cota, Goulart, Luiz Ricardo, de Melo Rodrigues Ávila, Veridiana

“…Phospholipases A (PLA ) represent a superfamily of enzymes widely distributed in living organisms, with a broad spectrum of pharmacological activities and…”
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Genotoxic effects of BnSP-6, a Lys-49 phospholipase A2 (PLA2) homologue from Bothrops pauloensis snake venom, on MDA-MB-231 breast cancer cells by Silva, Makswell Almeida, Lopes, Daiana Silva, Teixeira, Samuel Cota, Gimenes, Sarah Natalie Cirilo, Azevedo, Fernanda Van Petten Vasconcelos, Polloni, Lorena, Borges, Bruna Cristina, da Silva, Marcelo Santos, Barbosa, Marcelo José, Oliveira Júnior, Robson José de, Elias, Maria Carolina, da Silva, Claudio Vieira, Yoneyama, Kelly Aparecida Geraldo, Rodrigues, Veridiana de Melo, Rodrigues, Renata Santos

“…Herein we evaluated the genotoxic effects of BnSP-6, a Lys-49 phospholipase A2 (PLA2) from Bothrops pauloensis, on breast cancer cells. BnSP-6 was able to…”
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Antiangiogenic effects of phospholipase A 2 Lys49 BnSP-7 from Bothrops pauloensis snake venom on endothelial cells: An in vitro and ex vivo approach by Polloni, Lorena, Azevedo, Fernanda Van Petten Vasconcelos, Teixeira, Samuel Cota, Moura, Eloá, Costa, Tassia Rafaela, Gimenes, Sarah Natalie Cirilo, Correia, Lucas Ian Veloso, Freitas, Vitor, Yoneyama, Kelly Aparecida Geraldo, Rodrigues, Renata Santos, Lopes, Daiana Silva, Rodrigues, Veridiana de Melo

“…Antiangiogenic strategies are promising tools for cancer treatment and several other disorders. In this sense, phospholipases A (PLA s) from snake venom have…”
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Protective effect of aspirin against mitomycin C-induced carcinogenicity, assessed by the test for detection of epithelial tumor clones (warts) in Drosophila melanogaster by Oliveira, Victor Constante, Constante, Sarah Alves Rodrigues, Polloni, Lorena, Orsolin, Priscila Capelari, Silva-Oliveira, Rosiane Gomes, Machado, Nayane Moreira, de Oliveira-Júnior, Robson José, Nepomuceno, Júlio César

“…The present study assessed the protective effect of aspirin against carcinogenicity induced by mitomycin C (MMC) by the test for detection of warts/epithelial…”
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