Search Results - "Pollock, B G"

Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer’s disease by Roostaei, T, Nazeri, A, Felsky, D, De Jager, P L, Schneider, J A, Pollock, B G, Bennett, D A, Voineskos, A N

“…The lack of strong association between brain beta-amyloid deposition and cognitive impairment has been a challenge for the Alzheimer’s disease (AD) field…”
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In-vivo imaging of grey and white matter neuroinflammation in Alzheimer’s disease: a positron emission tomography study with a novel radioligand, [18F]-FEPPA by Suridjan, I, Pollock, B G, Verhoeff, N P L G, Voineskos, A N, Chow, T, Rusjan, P M, Lobaugh, N J, Houle, S, Mulsant, B H, Mizrahi, R

“…Our primary aim was to compare neuroinflammation in cognitively intact control subjects and patients with Alzheimer’s disease (AD) by using positron emission…”
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Genetic variation in CYP3A43 explains racial difference in olanzapine clearance by Bigos, K L, Bies, R R, Pollock, B G, Lowy, J J, Zhang, F, Weinberger, D R

“…The antipsychotic drug, olanzapine, one of the most widely used drugs in clinical medicine, has a high rate of discontinuation due to inefficacy and/or adverse…”
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Predicting Age-Specific Dosing of Antipsychotics by Uchida, H, Pollock, B G, Bies, R R, Mamo, D C

“…Antipsychotic medications are the standard of care for both acute and maintenance treatment of schizophrenia, the latter requiring an indefinite treatment…”
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The Critical Role of Clinical Pharmacology in Geriatric Psychopharmacology by Pollock, BG, Forsyth, CE, Bies, RR

“…There is limited geriatrics‐oriented clinical pharmacological information available to guide pharmacotherapy in late‐life psychiatric disorders. In this paper,…”
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Catechol-O-methyltransferase haplotypes are associated with psychosis in Alzheimer disease by SWEET, R. A, DEVLIN, POLLOCK, B. G, SUKONICK, D. L, KASTANGO, K. B, BACANU, S.-A, CHOWDARI, K. V, DEKOSKY, S. T, FERRELL, R. E

“…Psychotic symptoms in subjects with Alzheimer disease (AD with psychosis, AD+P) define a phenotype characterized by greater cognitive burden than in AD without…”
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Changes in Cognitive Functioning Following Treatment of Late-Life Depression by Butters, Meryl A., Becker, James T., Nebes, Robert D., Zmuda, Michelle D., Mulsant, Benoit H., Pollock, Bruce G., Reynolds, Charles F.

“…OBJECTIVE: Knowledge of the relationship between various clinical characteristics and cognitive functioning is advancing, but little is known about the…”
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Nortriptyline and Interpersonal Psychotherapy as Maintenance Therapies for Recurrent Major Depression: A Randomized Controlled Trial in Patients Older Than 59 Years by Reynolds III, Charles F, Frank, Ellen, Perel, James M, Imber, Stanley D, Cornes, Cleon, Miller, Mark D, Mazumdar, Sati, Houck, Patricia R, Dew, Mary Amanda, Stack, Jacqueline A, Pollock, Bruce G, Kupfer, David J

“…CONTEXT Elderly patients with major depression are at high risk for recurrence, increased mortality, and chronic disability. OBJECTIVE To determine the…”
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Decreased working memory and processing speed mediate cognitive impairment in geriatric depression by Nebes, R D, Butters, M A, Mulsant, B H, Pollock, B G, Zmuda, M D, Houck, P R, Reynolds, 3rd, C F

“…While neuropsychological dysfunction is common in geriatric depression, not all aspects of cognition are equally affected. It has been suggested that depressed…”
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Effect of dorsolateral prefrontal cortex structural measures on neuroplasticity and response to paired-associative stimulation in Alzheimer's dementia by Naveed, K, Rashidi-Ranjbar, N, Kumar, S, Zomorrodi, R, Blumberger, D M, Fischer, C E, Sanches, M, Mulsant, B H, Pollock, B G, Voineskos, A N, Rajji, T K

“…Long-term potentiation (LTP)-like activity can be induced by stimulation protocols such as paired associative stimulation (PAS). We aimed to determine whether…”
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Evaluation of platelet activation in depressed patients with ischemic heart disease after paroxetine or nortriptyline treatment by POLLOCK, B. G, LAGHRISSI-THODE, F, WAGNER, W. R

“…This study investigated the effects of antidepressant treatment on platelet activation in depressed patients with ischemic heart disease (IHD). Plasma levels…”
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Elevated platelet factor 4 and β-thromboglobulin plasma levels in depressed patients with ischemic heart disease by Laghrissi-Thode, Fouzia, Wagner, William R., Pollock, Bruce G., Johnson, Peter C., Finkel, Mitchell S.

“…Clinical depression has recently been recognized as an independent risk factor for cardiac mortality in patients after myocardial infarction. The underlying…”
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Comorbid Anxiety Disorders in Depressed Elderly Patients by Lenze, Eric J., Mulsant, Benoit H., Shear, M. Katherine, Schulberg, Herbert C., Dew, Mary Amanda, Begley, Amy E., Pollock, Bruce G., Reynolds, Charles F.

“…OBJECTIVE: Anxiety disorders are common in adults with depressive disorders, but several studies have suggested a relatively low prevalence of anxiety…”
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Serotonin in Aging, Late-Life Depression, and Alzheimer’s Disease: The Emerging Role of Functional Imaging by Meltzer, M.D, Carolyn Cidis, Smith, Ph.D, Gwenn, DeKosky, M.D, Steven T, Pollock, M.D., Ph.D, Bruce G, Mathis, Ph.D, Chester A, Moore, M.D., Ph.D, Robert Y, Kupfer, M.D, David J, Reynolds, M.D, Charles F

“…Serotonin (5-HT) neuron and neurotransmitter loss in normal aging and neuropsychiatric diseases of late life may contribute to behavioral changes commonly…”
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Newer antidepressants and the cytochrome P450 system by Nemeroff, C B, DeVane, C L, Pollock, B G

“…This review evaluates the in vitro and in vivo evidence for inhibition of cytochrome P450 enzymes by the newer antidepressants and provides clinical…”
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Comparison of Paroxetine and Nortriptyline in Depressed Patients With Ischemic Heart Disease by Roose, Steven P, Laghrissi-Thode, Fouzia, Kennedy, John S, Nelson, J. Craig, Bigger, Jr, J. Thomas, Pollock, Bruce G, Gaffney, Andrew, Narayan, Meena, Finkel, Mitchell S, McCafferty, James, Gergel, Ivan

“…CONTEXT.— Depression and ischemic heart disease often are comorbid conditions and, in patients who have had a myocardial infarction, the presence of depression…”
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Citalopram: a comprehensive review by Pollock, B G

“…Citalopram is a selective serotonin re-uptake inhibitor that has demonstrated antidepressant efficacy in numerous controlled clinical trials. Additional…”
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Serum anticholinergic activity, white matter hyperintensities, and cognitive performance by NEBES, R. D, POLLOCK, B. G, MELTZER, C. C, SAXTON, J. A, HOUCK, P. R, HALLIGAN, E. M, DEKOSKY, S. T

“…The authors investigated whether the cognitive impairments associated with white matter hyperintensities (WMH) in normal elderly subjects are exacerbated by…”
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Regression models in clinical studies: determining relationships between predictors and response by Harrell, Jr, F E, Lee, K L, Pollock, B G

“…Multiple regression models are increasingly being applied to clinical studies. Such models are powerful analytic tools that yield valid statistical inferences…”
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Inhibition of Caffeine Metabolism by Estrogen Replacement Therapy in Postmenopausal Women by Pollock, Bruce G., Wylie, Mary, Stack, Jacqueline A., Sorisio, Denise A., Thompson, Diane S., Kirshner, Margaret A., Folan, Maggie M., Condifer, Kelly A.

“…This study was conducted to investigate the effect of therapeutic estrogen on cytochrome P450 1A2‐mediated metabolism in postmenopausal women using caffeine as…”
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