Search Results - "Pollitt, Laura C."

Facilitation through altered resource availability in a mixed-species rodent malaria infection by Ramiro, Ricardo S., Pollitt, Laura C., Mideo, Nicole, Reece, Sarah E.

“…A major challenge in disease ecology is to understand how co‐infecting parasite species interact. We manipulate in vivo resources and immunity to explain…”
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Fitness consequences of immune responses: strengthening the empirical framework for ecoimmunology by Graham, Andrea L, Shuker, David M, Pollitt, Laura C, Auld, Stuart K.J.R, Wilson, Alastair J, Little, Tom J

“…1. Ecoimmunologists aim to understand the costs, benefits, and net fitness consequences of different strategies for immune defense. 2. Measuring the fitness…”
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Competition and the Evolution of Reproductive Restraint in Malaria Parasites by Pollitt, Laura C., Mideo, Nicole, Drew, Damien R., Schneider, Petra, Colegrave, Nick, Reece, Sarah E.

“…All organisms must trade off resource allocation between different life processes that determine their survival and reproduction. Malaria parasites replicate…”
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The meaning of death: evolution and ecology of apoptosis in protozoan parasites by Reece, Sarah E, Pollitt, Laura C, Colegrave, Nick, Gardner, Andy

“…The discovery that an apoptosis-like, programmed cell death (PCD) occurs in a broad range of protozoan parasites offers novel therapeutic tools to treat some…”
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Existing Infection Facilitates Establishment and Density of Malaria Parasites in Their Mosquito Vector by Pollitt, Laura C, Bram, Joshua T, Blanford, Simon, Jones, Matthew J, Read, Andrew F

“…Very little is known about how vector-borne pathogens interact within their vector and how this impacts transmission. Here we show that mosquitoes can…”
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The problem of auto-correlation in parasitology by Pollitt, Laura C, Reece, Sarah E, Mideo, Nicole, Nussey, Daniel H, Colegrave, Nick

“…Explaining the contribution of host and pathogen factors in driving infection dynamics is a major ambition in parasitology. There is increasing recognition…”
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Rapid response to selection, competitive release and increased transmission potential of artesunate-selected Plasmodium chabaudi malaria parasites by Pollitt, Laura C, Huijben, Silvie, Sim, Derek G, Salathé, Rahel M, Jones, Matthew J, Read, Andrew F

“…The evolution of drug resistance, a key challenge for our ability to treat and control infections, depends on two processes: de-novo resistance mutations, and…”
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Costs of crowding for the transmission of malaria parasites by Pollitt, Laura. C., Churcher, Thomas S., Dawes, Emma J., Khan, Shahid M., Sajid, Mohammed, Basáñez, María‐Gloria, Colegrave, Nick, Reece, Sarah E.

“…The utility of using evolutionary and ecological frameworks to understand the dynamics of infectious diseases is gaining increasing recognition. However,…”
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Investigating the evolution of apoptosis in malaria parasites: the importance of ecology by Pollitt, Laura C, Colegrave, Nick, Khan, Shahid M, Sajid, Mohammed, Reece, Sarah E

“…Apoptosis is a precisely regulated process of cell death which occurs widely in multicellular organisms and is essential for normal development and immune…”
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The path of least resistance: aggressive or moderate treatment? by Kouyos, Roger D., Metcalf, C. Jessica E., Birger, Ruthie, Klein, Eili Y., Abel zur Wiesch, Pia, Ankomah, Peter, Arinaminpathy, Nimalan, Bogich, Tiffany L., Bonhoeffer, Sebastian, Brower, Charles, Chi-Johnston, Geoffrey, Cohen, Ted, Day, Troy, Greenhouse, Bryan, Huijben, Silvie, Metlay, Joshua, Mideo, Nicole, Pollitt, Laura C., Read, Andrew F., Smith, David L., Standley, Claire, Wale, Nina, Grenfell, Bryan

“…The evolution of resistance to antimicrobial chemotherapy is a major and growing cause of human mortality and morbidity. Comparatively little attention has…”
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Malaria and trypanosome transmission: different parasites, same rules? by Pollitt, Laura C, MacGregor, Paula, Matthews, Keith, Reece, Sarah E

“…African trypanosomes produce different specialized stages for within-host replication and between-host transmission and therefore face a resource allocation…”
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Ecological influences on the behaviour and fertility of malaria parasites by Carter, Lucy M, Pollitt, Laura C, Wilson, Laurence G, Reece, Sarah E

“…Sexual reproduction in the mosquito is essential for the transmission of malaria parasites and a major target for transmission-blocking interventions. Male…”
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Understanding genetic variation in in vivo tolerance to artesunate: implications for treatment efficacy and resistance monitoring by Pollitt, Laura C., Sim, Derek, Salathé, Rahel, Read, Andrew F.

“…Artemisinin‐based drugs are the front‐line weapon in the treatment of human malaria cases, but there is concern that recent reports of slow clearing infections…”
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Temporal patterns in immune responses to a range of microbial insults ( Tenebrio molitor) by Haine, Eleanor R., Pollitt, Laura C., Moret, Yannick, Siva-Jothy, Michael T., Rolff, Jens

“…Much work has elucidated the pathways and mechanisms involved in the production of insect immune effector systems. However, the temporal nature of these…”
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Mosquito transmission, growth phenotypes and the virulence of malaria parasites by Pollitt, Laura C, Mackinnon, Margaret J, Mideo, Nicole, Read, Andrew F

“…A series of elegant experiments was recently published which demonstrated that transmission of malaria parasites through mosquitoes elicited an attenuated…”
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Stress and sex in malaria parasites: Why does commitment vary? by Carter, Lucy M, Kafsack, Björn F C, Llinás, Manuel, Mideo, Nicole, Pollitt, Laura C, Reece, Sarah E

“…For vector-borne parasites such as malaria, how within- and between-host processes interact to shape transmission is poorly understood. In the host, malaria…”
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Existing Infection Facilitates Establishment and Density of Malaria Parasites in Their Mosquito Vector: e1005003 by Pollitt, Laura C, Bram, Joshua T, Blanford, Simon, Jones, Matthew J, Read, Andrew F

“…Very little is known about how vector-borne pathogens interact within their vector and how this impacts transmission. Here we show that mosquitoes can…”
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Rapid Response to Selection, Competitive Release and Increased Transmission Potential of Artesunate-Selected Plasmodium chabaudi Malaria Parasites: e1004019 by Pollitt, Laura C, Huijben, Silvie, Sim, Derek G, Salathé, Rahel M, Jones, Matthew J, Read, Andrew F

“…The evolution of drug resistance, a key challenge for our ability to treat and control infections, depends on two processes: de-novo resistance mutations, and…”
Get full text

The path of least resistance: aggressive or moderate treatment? by Kouyos, Roger D., Metcalf, C. Jessica E., Birger, Ruthie, Klein, Eili Y., zur Wiesch, Pia Abel, Ankomah, Peter, Arinaminpathy, Nimalan, Bogich, Tiffany L., Bonhoeffer, Sebastian, Brower, Charles, Chi-Johnston, Geoffrey, Cohen, Ted, Day, Troy, Greenhouse, Bryan, Huijben, Silvie, Metlay, Joshua, Mideo, Nicole, Pollitt, Laura C., Read, Andrew F., Smith, David L., Standley, Claire, Wale, Nina, Grenfell, Bryan

“…The evolution of resistance to antimicrobial chemotherapy is a major and growing cause of human mortality and morbidity. Comparatively little attention has…”
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ECOLOGICAL IMMUNOLOGY: Fitness consequences of immune responses: strengthening the empirical framework for ecoimmunology by Graham, Andrea L., Shuker, David M., Pollitt, Laura C., Auld, Stuart K. J. R., Wilson, Alastair J., Little, Tom J.

“…1. Ecoimmuriologists aim to understand the costs, benefits, and net fitness consequences of different strategies for immune defense. 2. Measuring the fitness…”
Get full text