Search Results - "Pollicita, Michela"

Different Patterns of HIV-1 Replication in MACROPHAGES is Led by Co-Receptor Usage by Borrajo, Ana, Ranazzi, Alessandro, Pollicita, Michela, Bellocchi, Maria Concetta, Salpini, Romina, Mauro, Maria Vittoria, Ceccherini-Silberstein, Francesca, Perno, Carlo Federico, Svicher, Valentina, Aquaro, Stefano

“…To enter the target cell, HIV-1 binds not only CD4 but also a co-receptor β-chemokine receptor 5 (CCR5) or α chemokine receptor 4 (CXCR4). Limited information…”
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Effects of Amprenavir on HIV-1 Maturation, Production and Infectivity Following Drug Withdrawal in Chronically-Infected Monocytes/Macrophages by Borrajo, Ana, Ranazzi, Alessandro, Pollicita, Michela, Bruno, Rosalinda, Modesti, Andrea, Alteri, Claudia, Perno, Carlo Federico, Svicher, Valentina, Aquaro, Stefano

“…A paucity of information is available on the activity of protease inhibitors (PI) in chronically-infected monocyte-derived macrophages (MDM) and on the…”
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Secondary Integrase Resistance Mutations Found in HIV-1 Minority Quasispecies in Integrase Therapy-Naive Patients Have Little or No Effect on Susceptibility to Integrase Inhibitors by Ceccherini-Silberstein, Francesca, Van Baelen, Kurt, Armenia, Daniele, Trignetti, Maria, Rondelez, Evelien, Fabeni, Lavinia, Scopelliti, Fernanda, Pollicita, Michela, Van Wesenbeeck, Liesbeth, Van Eygen, Veerle, Dori, Luca, Sarmati, Loredana, Aquaro, Stefano, Palamara, Guido, Andreoni, Massimo, Stuyver, Lieven J, Perno, Carlo Federico

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Mechanisms underlying activity of antiretroviral drugs in HIV-1-infected macrophages: new therapeutic strategies by Aquaro, Stefano, Svicher, Valentina, Schols, Dominique, Pollicita, Michela, Antinori, Andrea, Balzarini, Jan, Perno, Carlo Federico

“…Monocyte‐derived macrophages (M/M) are considered the second cellular target of HIV‐1 and a crucial virus reservoir. M/M are widely distributed in all tissues…”
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Therapeutic strategies towards HIV-1 infection in macrophages by Perno, Carlo Federico, Svicher, Valentina, Schols, Dominique, Pollicita, Michela, Balzarini, Jan, Aquaro, Stefano

“…It is widely recognized that macrophages (M/M) represent a crucial target of HIV-1 in the body and play a pivotal role in the pathogenic progression of HIV-1…”
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The contribution of peroxynitrite generation in HIV replication in human primary macrophages by Aquaro, Stefano, Muscoli, Carolina, Ranazzi, Alessandro, Pollicita, Michela, Granato, Teresa, Masuelli, Laura, Modesti, Andrea, Perno, Carlo-Federico, Mollace, Vincenzo

“…Monocytes/Macrophages (M/M) play a pivotal role as a source of virus during the whole course of HIV-1 infection. Enhanced oxidative stress is involved in the…”
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Novel In Vivo Model for the Study of Human Immunodeficiency Virus Type 1 Transcription Inhibitors: Evaluation of New 6-Desfluoroquinolone Derivatives by STEVENS, Miguel, POLLICITA, Michela, SCHOLS, Dominique, BALZARINI, Jan, PANNECOUQUE, Christophe, VERBEKEN, Erik, TABARRINI, Oriana, CECCHETTI, Violetta, AQUARO, Stefano, PERNO, Carlo Federico, FRAVOLINI, Arnaldo, DE CLERCQ, Erik

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Apoptosis and telomeres shortening related to HIV-1 induced oxidative stress in an astrocytoma cell line by Pollicita, Michela, Muscoli, Carolina, Sgura, Antonella, Biasin, Alberto, Granato, Teresa, Masuelli, Laura, Mollace, Vincenzo, Tanzarella, Caterina, Del Duca, Claudio, Rodinò, Paola, Perno, Carlo Federico, Aquaro, Stefano

“…Oxidative stress plays a key role in the neuropathogenesis of Human Immunodeficiency Virus-1 (HIV-1) infection causing apoptosis of astroglia cells and…”
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HIV-1-associated dementia during HAART therapy by Aquaro, Stefano, Svicher, Valentina, Ronga, Luigi, Perno, Carlo F, Pollicita, Michela

“…Human immunodeficiency virus (HIV-1) is the responsible agent of acquired immunodeficiency syndrome (AIDS), a multi system disorder including the central…”
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Profound Anti-HIV-1 Activity of DAPTA in Monocytes/macrophages and Inhibition of CCR5-mediated Apoptosis in Neuronal Cells by Pollicita, Michela, Ruff, Michael R, Pert, Candace B, Polianova, Maria T, Schols, Dominique, Ranazzi, Alessandro, Perno, Carlo-Federico, Aquaro, Stefano

“…Monocytes/macrophages (M/M) are strategic reservoirs of HIV-1, spreading the virus to other cells and inducing apoptosis in T-lymphocytes, astrocytes and…”
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Hepatitis B surface antigen genetic elements critical for immune escape correlate with hepatitis B virus reactivation upon immunosuppression by Salpini, Romina, Colagrossi, Luna, Bellocchi, Maria Concetta, Surdo, Matteo, Becker, Christina, Alteri, Claudia, Aragri, Marianna, Ricciardi, Alessandra, Armenia, Daniele, Pollicita, Michela, Di Santo, Fabiola, Carioti, Luca, Louzoun, Yoram, Mastroianni, Claudio Maria, Lichtner, Miriam, Paoloni, Maurizio, Esposito, Mariarosaria, D'Amore, Chiara, Marrone, Aldo, Marignani, Massimo, Sarrecchia, Cesare, Sarmati, Loredana, Andreoni, Massimo, Angelico, Mario, Verheyen, Jens, Perno, Carlo‐Federico, Svicher, Valentina

“…Hepatitis B virus (HBV) reactivation during immunosuppression can lead to severe acute hepatitis, fulminant liver failure, and death. Here, we investigated…”
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Multiple Hepatitis B Virus (HBV) Quasispecies and Immune-Escape Mutations Are Present in HBV Surface Antigen and Reverse Transcriptase of Patients With Acute Hepatitis B by Aragri, Marianna, Alteri, Claudia, Battisti, Arianna, Di Carlo, Domenico, Minichini, Carmine, Sagnelli, Caterina, Bellocchi, Maria Concetta, Pisaturo, Maria Antonietta, Starace, Mario, Armenia, Daniele, Carioti, Luca, Pollicita, Michela, Salpini, Romina, Sagnelli, Evangelista, Perno, Carlo Federico, Coppola, Nicola, Svicher, Valentina

“…Background. This study characterizes and defines the clinical value of hepatitis B virus (HBV) quasispecies with reverse transcriptase and HBV surface antigen…”
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Nucleotide polymorphisms in the 5′-UTR region of HCV can affect the ability of two widely used assays to assign an HCV genotype by Pollicita, Michela, Cento, Valeria, Paba, Pierpaolo, Perno, Carlo Federico, Ciotti, Marco

“…•Correct HCV genotyping is crucial in the management of patients with chronic hepatitis C infection.•Based on the HCV genotype, antiviral therapy can last 24…”
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Comparative antiviral activity of integrase inhibitors in human monocyte-derived macrophages and lymphocytes by Scopelliti, Fernanda, Pollicita, Michela, Ceccherini-Silberstein, Francesca, Di Santo, Fabiola, Surdo, Matteo, Aquaro, Stefano, Perno, Carlo-Federico

“…► We investigated the anti HIV activity of integrase inhibitors (INIs) in macrophages, PBMC and C8166 T lymphocytes. ► Raltegravir and the other INIs showed…”
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A snapshot of virological presentation and outcome of immunosuppression‐driven HBV reactivation from real clinical practice: Evidence of a relevant risk of death and evolution from silent to chronic infection by Salpini, Romina, Battisti, Arianna, Colagrossi, Luna, Di Carlo, Domenico, Fabeni, Lavinia, Piermatteo, Lorenzo, Cerva, Carlotta, Lichtner, Miriam, Mastroianni, Claudio, Marignani, Massimo, Maylin, Sarah, Delaugerre, Constance, Morisco, Filomena, Coppola, Nicola, Marrone, Aldo, Angelico, Mario, Sarmati, Loredana, Andreoni, Massimo, Perno, Carlo‐Federico, Ceccherini‐Silberstein, Francesca, Svicher, Valentina, Bertoli, Ada, Fini, Vanessa, Pollicita, Michela, Salpini, Romina, Maffongelli, Gaetano, Ricciardi, Alessandra, Sarrecchia, Cesare, Baiocchi, Leonardo, Brega, Arianna, Daniele Di Paolo, Francioso, Simona, Lenci, Ilaria, Arcese, William, Cudillo, Laura, Mariotti, Benedetta, Claudio Miriam Lichtner, Marocco, Raffaella, Mastroianni, Maria, Taliani, Gloria, Tieghi, Tiziana, Esposito, Maria Rosaria, Mari, Terenzio, Mazzoni, Ettore, Spaziani, Fabrizio, Casinelli, Katia, Paoloni, Maurizio, Iapadre, Nerio, Grimaldi, Alessandro, Begini, Paola, Imperatrice, Barbara, Vanvitelli, Luigi, Macera, Margherita, Pisaturo, Mariantonietta, Vanvitelli, Luigi, more, Chiara, Siniscalchi, Isabella, Esposito, Maria Rosaria

“…The study was undertaken in order to provide a snapshot from real clinical practice of virological presentation and outcome of patients developing…”
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Comparative replication capacity of raltegravir-resistant strains and antiviral activity of the new-generation integrase inhibitor dolutegravir in human primary macrophages and lymphocytes by Pollicita, Michela, Surdo, Matteo, Di Santo, Fabiola, Cortese, Maria Francesca, Fabeni, Lavinia, Fedele, Valentina, Malet, Isabelle, Marcelin, Anne-Genevieve, Calvez, Vincent, Ceccherini-Silberstein, Francesca, Perno, Carlo Federico, Svicher, Valentina

“…To evaluate the replication capacity and phenotypic susceptibility to dolutegravir and raltegravir of wild-type and raltegravir-resistant HIV-1 strains in…”
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Thymosin α 1 potentiates the release by CD8(+) cells of soluble factors able to inhibit HIV-1 and human T lymphotropic virus 1 infection in vitro by Matteucci, Claudia, Minutolo, Antonella, Pollicita, Michela, Balestrieri, Emanuela, Grelli, Sandro, D'Ettorre, Gabriella, Vullo, Vincenzo, Bucci, Ilaria, Luchini, Alessandra, Aquaro, Stefano, Sinibaldi-Vallebona, Paola, Macchi, Beatrice, Perno, Carlo Federico, Mastino, Antonio, Garaci, Enrico

“…Thymosin α-1 (Tα1) exploits a specific action on lymphoid cells and is able to induce in peripheral blood mononuclear cells (PBMCs) a strong transcriptional…”
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Specific mutations in the C-terminus domain of HBV surface antigen significantly correlate with low level of serum HBV-DNA in patients with chronic HBV infection by Mirabelli, Carmen, Surdo, Matteo, Van Hemert, Formijn, Lian, Zhichao, Salpini, Romina, Cento, Valeria, Cortese, Maria Francesca, Aragri, Marianna, Pollicita, Michela, Alteri, Claudia, Bertoli, Ada, Berkhout, Ben, Micheli, Valeria, Gubertini, Guido, Santoro, Maria Mercedes, Romano, Sara, Visca, Michela, Bernassola, Martina, Longo, Roberta, De Sanctis, Giuseppe Maria, Trimoulet, Pascal, Fleury, Hervè, Marino, Nicoletta, Mazzotta, Francesco, Cappiello, Giuseppina, Spanò, Alberto, Sarrecchia, Cesare, Zhang, Jing Maria, Andreoni, Massimo, Angelico, Mario, Verheyen, Jens, Perno, Carlo Federico, Svicher, Valentina

“…Summary Background To define HBsAg-mutations correlated with different serum HBV-DNA levels in HBV chronically-infected drug-naive patients. Methods This study…”
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Novel HBsAg mutations correlate with hepatocellular carcinoma, hamper HBsAg secretion and promote cell proliferation in vitro by Salpini, Romina, Surdo, Matteo, Warner, Nadia, Cortese, Maria Francesca, Colledge, Danny, Soppe, Sally, Bellocchi, Maria Concetta, Armenia, Daniele, Carioti, Luca, Continenza, Fabio, Di Carlo, Domenico, Saccomandi, Patrizia, Mirabelli, Carmen, Pollicita, Michela, Longo, Roberta, Romano, Sara, Cappiello, Giuseppina, Spanò, Alberto, Trimoulet, Pascale, Fleury, Herve, Vecchiet, Jacopo, Iapadre, Nerio, Barlattani, Angelo, Bertoli, Ada, Mari, Terenzio, Pasquazzi, Caterina, Missale, Gabriele, Sarrecchia, Cesare, Orecchini, Elisa, Michienzi, Alessandro, Andreoni, Massimo, Francioso, Simona, Angelico, Mario, Verheyen, Jens, Ceccherini-Silberstein, Francesca, Locarnini, Stephen, Perno, Carlo Federico, Svicher, Valentina

“…An impaired HBsAg-secretion can increase HBV oncogenic-properties. Here, we investigate genetic-determinants in HBsAg correlated with HBV-induced…”
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Telomerase activity, hTERT expression, and phosphorylation are downregulated in CD4+ T lymphocytes infected with human immunodeficiency virus type 1 (HIV-1) by Franzese, Ornella, Adamo, Riccardo, Pollicita, Michela, Comandini, Alessandro, Laudisi, Anastasia, Perno, Carlo Federico, Aquaro, Stefano, Bonmassar, Enzo

“…Human immunodeficiency virus type 1 (HIV‐1) infection is characterized by a progressive decrease of CD4+ T cells accompanied by other immune dysfunctions…”
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