Search Results - "Pollard, R"

Designed ultrafast optical nonlinearity in a plasmonic nanorod metamaterial enhanced by nonlocality by Hendren, W, Podolskiy, V. A, Wurtz, G. A, Gosztola, D. J, Pollard, R, Wiederrecht, G. P, Zayats, A. V

“…All-optical signal processing enables modulation and transmission speeds not achievable using electronics alone 1 , 2 . However, its practical applications are…”
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Discovery and Development of Aurora Kinase Inhibitors as Anticancer Agents by Pollard, John R, Mortimore, Michael

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ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A by Williamson, Chris T., Miller, Rowan, Pemberton, Helen N., Jones, Samuel E., Campbell, James, Konde, Asha, Badham, Nicholas, Rafiq, Rumana, Brough, Rachel, Gulati, Aditi, Ryan, Colm J., Francis, Jeff, Vermulen, Peter B., Reynolds, Andrew R., Reaper, Philip M., Pollard, John R., Ashworth, Alan, Lord, Christopher J.

“…Identifying genetic biomarkers of synthetic lethal drug sensitivity effects provides one approach to the development of targeted cancer therapies. Mutations in…”
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Long-term efficacy and safety of thalamic stimulation for drug-resistant partial epilepsy by Salanova, Vicenta, Witt, Thomas, Worth, Robert, Henry, Thomas R, Gross, Robert E, Nazzaro, Jules M, Labar, Douglas, Sperling, Michael R, Sharan, Ashwini, Sandok, Evan, Handforth, Adrian, Stern, John M, Chung, Steve, Henderson, Jaimie M, French, Jacqueline, Baltuch, Gordon, Rosenfeld, William E, Garcia, Paul, Barbaro, Nicholas M, Fountain, Nathan B, Elias, W Jeffrey, Goodman, Robert R, Pollard, John R, Tröster, Alexander I, Irwin, Christopher P, Lambrecht, Kristin, Graves, Nina, Fisher, Robert

“…OBJECTIVE:To report long-term efficacy and safety results of the SANTE trial investigating deep brain stimulation of the anterior nucleus of the thalamus (ANT)…”
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Uterine pathology in transmasculine persons on testosterone: a retrospective multicenter case series by Grimstad, Frances W., Fowler, Kylie G., New, Erika P., Ferrando, Cecile A., Pollard, Robert R., Chapman, Graham, Gomez-Lobo, Veronica, Gray, Meredith

“…As part of transition, transmasculine persons often use testosterone gender-affirming hormone therapy; however, there is limited data on its long-term effects…”
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Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities by Sanjiv, Kumar, Hagenkort, Anna, Calderón-Montaño, José Manuel, Koolmeister, Tobias, Reaper, Philip M., Mortusewicz, Oliver, Jacques, Sylvain A., Kuiper, Raoul V., Schultz, Niklas, Scobie, Martin, Charlton, Peter A., Pollard, John R., Berglund, Ulrika Warpman, Altun, Mikael, Helleday, Thomas

“…ATR and CHK1 maintain cancer cell survival under replication stress and inhibitors of both kinases are currently undergoing clinical trials. As ATR activity is…”
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Optical bistability in nonlinear surface-plasmon polaritonic crystals by Wurtz, G A, Pollard, R, Zayats, A V

“…Nonlinear optical transmission through periodically nanostructured metal films (surface-plasmon polaritonic crystals) has been studied. The surface polaritonic…”
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Plasmonic nanorod metamaterials for biosensing by Zayats, A. V, Kabashin, A. V, Evans, P, Pastkovsky, S, Hendren, W, Wurtz, G. A, Atkinson, R, Pollard, R, Podolskiy, V. A

“…Label-free plasmonic biosensors rely either on surface plasmon polaritons or on localized surface plasmons on continuous or nanostructured noble-metal surfaces…”
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Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR by Reaper, Philip M, Griffiths, Matthew R, Long, Joanna M, Charrier, Jean-Damien, MacCormick, Somhairle, Charlton, Peter A, Golec, Julian M C, Pollard, John R

“…A specific and potent inhibitor of the DNA damage response kinase ATR can exploit synthetic lethality between ATR and the related kinase ATM to sensitize…”
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On a handshake: business-to-business trust in the biosecurity behaviours of the UK live plant trade by Pollard, Chris R. J., Marzano, Mariella

“…The movement of plants through the ornamental plant trade presents a major source of risk for the introduction and spread of plant pests and pathogens. To…”
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ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses by Jossé, Rozenn, Martin, Scott E, Guha, Rajarshi, Ormanoglu, Pinar, Pfister, Thomas D, Reaper, Philip M, Barnes, Christopher S, Jones, Julie, Charlton, Peter, Pollard, John R, Morris, Joel, Doroshow, James H, Pommier, Yves

“…Camptothecin and its derivatives, topotecan and irinotecan, are specific topoisomerase I (Top1) inhibitors and potent anticancer drugs killing cancer cells by…”
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Mesoscale Iron Enrichment Experiments 1993-2005: Synthesis and Future Directions by Boyd, P. W., Jickells, T., Law, C. S., Blain, S., Boyle, E. A., Buesseler, K. O., Coale, K. H., Cullen, J. J., de Baar, H. J. W., Follows, M., Harvey, M., Lancelot, C., Levasseur, M., Owens, N. P. J., Pollard, R., Rivkin, R. B., Sarmiento, J., Schoemann, V., Smetacek, V., Takeda, S., Tsuda, A., Turner, S., Watson, A. J.

“…Since the mid-1980s, our understanding of nutrient limitation of oceanic primary production has radically changed. Mesoscale iron addition experiments (FeAXs)…”
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The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy by Prevo, Remko, Fokas, Emmanouil, Reaper, Philip M., Charlton, Peter A., Pollard, John R., McKenna, W. Gillies, Muschel, Ruth J., Brunner, Thomas B.

“…DNA damaging agents such as radiotherapy and gemcitabine are frequently used for the treatment of pancreatic cancer. However, these treatments typically…”
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Long-term trends in home advantage in professional team sports in North America and England (1876 - 2003) by Pollard, R, Pollard, G

“…Home advantage is quantitatively defined and calculated for each season since the start of the main professional sports in North America and England. Over…”
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Stop Before You Block stickers by Pollard, R., Sivasubramaniam, S.

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Compositae‐ParaLoss‐1272: A complementary sunflower‐specific probe set reduces paralogs in phylogenomic analyses of complex systems by Moore‐Pollard, Erika R., Jones, Daniel S., Mandel, Jennifer R.

“…Premise A family‐specific probe set for sunflowers, Compositae‐1061, enables family‐wide phylogenomic studies and investigations at lower taxonomic levels, but…”
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Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation by Fokas, E, Prevo, R, Pollard, J R, Reaper, P M, Charlton, P A, Cornelissen, B, Vallis, K A, Hammond, E M, Olcina, M M, Gillies McKenna, W, Muschel, R J, Brunner, T B

“…Combined radiochemotherapy is the currently used therapy for locally advanced pancreatic ductal adenocarcinoma (PDAC), but normal tissue toxicity limits its…”
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In Vivo Quantification of Peroxisome Tethering to Chloroplasts in Tobacco Epidermal Cells Using Optical Tweezers by Gao, Hongbo, Metz, Jeremy, Teanby, Nick A., Ward, Andy D., Botchway, Stanley W., Coles, Benjamin, Pollard, Mark R., Sparkes, Imogen

“…Peroxisomes are highly motile organelles that display a range of motions within a short time frame. In static snapshots, they can be juxtaposed to…”
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Potentiation of tumor responses to DNA damaging therapy by the selective ATR inhibitor VX-970 by Hall, Amy B, Newsome, Dave, Wang, Yuxin, Boucher, Diane M, Eustace, Brenda, Gu, Yong, Hare, Brian, Johnson, Mac A, Milton, Sean, Murphy, Cheryl E, Takemoto, Darin, Tolman, Crystal, Wood, Mark, Charlton, Peter, Charrier, Jean-Damien, Furey, Brinley, Golec, Julian, Reaper, Philip M, Pollard, John R

“…Platinum-based DNA-damaging chemotherapy is standard-of-care for most patients with lung cancer but outcomes remain poor. This has been attributed, in part, to…”
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Targeting radiation-resistant hypoxic tumour cells through ATR inhibition by Pires, I M, Olcina, M M, Anbalagan, S, Pollard, J R, Reaper, P M, Charlton, P A, McKenna, W G, Hammond, E M

“…Background: Most solid tumours contain regions of sub-optimal oxygen concentration (hypoxia). Hypoxic cancer cells are more resistant to radiotherapy and…”
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