Search Results - "Pollack, Sarah F."
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CDK 4/6 Inhibitors Sensitize PIK3CA Mutant Breast Cancer to PI3K Inhibitors
Published in Cancer cell (14-07-2014)“…Activation of the phosphoinositide 3-kinase (PI3K) pathway occurs frequently in breast cancer. However, clinical results of single-agent PI3K inhibitors have…”
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Cannabidiol as a new treatment for drug‐resistant epilepsy in tuberous sclerosis complex
Published in Epilepsia (Copenhagen) (01-10-2016)“…Summary Objective Tuberous sclerosis complex (TSC) is an autosomal‐dominant genetic disorder with highly variable expression. The most common neurologic…”
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BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors
Published in Cancer discovery (01-09-2011)“…Cancers with specific genetic mutations are susceptible to selective kinase inhibitors. However, there is a wide spectrum of benefit among cancers harboring…”
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Drug–drug interaction between clobazam and cannabidiol in children with refractory epilepsy
Published in Epilepsia (Copenhagen) (01-08-2015)“…Summary Objective Under an expanded access investigational new drug (IND) trial, cannabidiol (CBD) is being studied as a possible adjuvant treatment of…”
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Cannabidiol in treatment of refractory epileptic spasms: An open-label study
Published in Epilepsy & behavior (01-05-2020)“…This study aimed to evaluate clinical efficacy and safety of purified pharmaceutical cannabidiol (CBD) as an adjunctive therapy in refractory childhood-onset…”
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Myoclonus in Angelman syndrome
Published in Epilepsy & behavior (01-05-2018)“…Angelman syndrome (AS) is a neurogenetic imprinting disorder caused by loss of the maternally inherited Ube3a gene and is characterized by generalized…”
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Primary intestinal lymphangiectasia treated with rapamycin in a child with tuberous sclerosis complex (TSC)
Published in American journal of medical genetics. Part A (01-09-2015)“…Primary intestinal lymphangiectasia (PIL) is a rare protein‐losing enteropathy characterized by a congenital malformation of the lymphatic vessels of the small…”
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Gastrointestinal problems in 15q duplication syndrome
Published in European journal of medical genetics (01-03-2015)“…Abstract Chromosome 15q duplication syndrome (Dup15q syndrome) is a neurodevelopmental disorder involving copy number gains of the maternal chromosome…”
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