Search Results - "Polkey, MI"

Inspiratory pressure support prolongs exercise induced lactataemia in severe COPD by Polkey, Michael I, Hawkins, Peter, Kyroussis, Dimitris, Ellum, Sheric G, Sherwood, Roy, Moxham, John

“…BACKGROUND A physiological benefit from pulmonary rehabilitation in chronic obstructive pulmonary disease (COPD) is more probable if exercise is performed…”
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The prevalence of quadriceps weakness in COPD and the relationship with disease severity by SEYMOUR, J. M, SPRUIT, M. A, WOUTERS, E. F. M, HOPKINSON, N. S, NATANEK, S. A, MAN, W. D-C, JACKSON, A, GOSKER, H. R, SCHOLS, A. M. W. J, MOXHAM, J, POLKEY, M. I

“…Quadriceps strength relates to exercise capacity and prognosis in chronic obstructive pulmonary disease (COPD). We wanted to quantify the prevalence of…”
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Angiotensin-Converting Enzyme Inhibition as an Adjunct to Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease by Curtis, Katrina J, Meyrick, Victoria M, Mehta, Bhavin, Haji, Gulam S, Li, Kawah, Montgomery, Hugh, Man, William D-C, Polkey, Michael I, Hopkinson, Nicholas S

“…Epidemiological studies in older individuals have found an association between the use of angiotensin-converting enzyme (ACE) inhibition (ACE-I) therapy and…”
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Community pulmonary rehabilitation after hospitalisation for acute exacerbations of chronic obstructive pulmonary disease: randomised controlled study by D-C Man, William, Polkey, Michael I, Donaldson, Nora, Gray, Barry J, Moxham, John

“…Abstract Objective To evaluate the effects of an early community based pulmonary rehabilitation programme after hospitalisation for acute exacerbations of…”
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Progression of physical inactivity in COPD patients: the effect of time and climate conditions - a multicenter prospective cohort study by Boutou, Afroditi K, Raste, Yogini, Demeyer, Heleen, Troosters, Thierry, Polkey, Michael I, Vogiatzis, Ioannis, Louvaris, Zafeiris, Rabinovich, Roberto A, van der Molen, Thys, Garcia-Aymerich, Judith, Hopkinson, Nicholas S

“…Longitudinal data on the effect of time and environmental conditions on physical activity (PA) among COPD patients are currently scarce, but this is an…”
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Cough augmentation with mechanical insufflation/exsufflation in patients with neuromuscular weakness by Chatwin, M, Ross, E, Hart, N, Nickol, A.H, Polkey, M.I, Simonds, A.K

“…Adults and children with neuromuscular disease exhibit weak cough and are susceptible to recurrent chest infections, a major cause of morbidity and mortality…”
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Request for regulatory guidance for cancer cachexia intervention trials by Fearon, KCH, Argiles, JM, Baracos, VE, Bernabei, R, Coats, AJS, Crawford, J, Deutz, NE, Doehner, W, Evans, WJ, Ferrucci, L, Garcia, JM, Gralla, RJ, Jatoi, A, Kalantar‐Zadeh, K, Lainscak, M, Morley, JE, Muscaritoli, M, Polkey, MI, Rosano, G, Rossi‐Fanelli, F, Schols, AM, Strasser, F, Vellas, B, Haehling, S, Anker, SD

“…In the last 10 years, some regulatory authorities have consistently suggested that the design of randomized controlled trials testing treatments for cachexia…”
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Depression symptoms reduce physical activity in COPD patients: a prospective multicenter study by Dueñas-Espín, Iván, Demeyer, Heleen, Gimeno-Santos, Elena, Polkey, Michael I, Hopkinson, Nicholas S, Rabinovich, Roberto A, Dobbels, Fabienne, Karlsson, Niklas, Troosters, Thierry, Garcia-Aymerich, Judith

“…The role of anxiety and depression in the physical activity (PA) of patients with COPD is controversial. We prospectively assessed the effect of symptoms of…”
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Effect of Bronchoscopic Lung Volume Reduction on Dynamic Hyperinflation and Exercise in Emphysema by Hopkinson, Nicholas S, Toma, Tudor P, Hansell, David M, Goldstraw, Peter, Moxham, John, Geddes, Duncan M, Polkey, Michael I

“…Endobronchial valve placement improves pulmonary function in some patients with chronic obstructive pulmonary disease, but its effects on exercise physiology…”
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Gender Differences in Prevalence of Sleepy Driving Among Young Drivers in Saudi Arabia by Alqurashi, Yousef D, Alqarni, Abdullah S, Albukhamsin, Faisal Maher, Alfaris, Abdullah Abdulaziz, Alhassan, Bader Ibrahim, Ghazwani, Waleed Khalid, Altammar, Abdulaziz Abdulrahman, Aleid, Mutlaq Eid, Almutary, Hayfa, Aldhahir, Abdulelah M, Alessy, Saleh A, Almusally, Rayyan, Alsaid, Abir, Mahmoud, Mahmoud Ibrahim, Qutub, Hatem Othman, Sebastian, Tunny, Alghnam, Suliman, Polkey, Michael I

“…Sleepy driving is associated with Motor Vehicles Accidents (MVAs). In Saudi Arabia, previous studies have addressed this association among men only. Therefore,…”
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Bronchoscopic volume reduction with valve implants in patients with severe emphysema by Toma, Tudor P, Hopkinson, Nicholas S, Hillier, James, Hansell, David M, Morgan, Clifford, Goldstraw, Peter G, Polkey, Michael I, Geddes, Duncan M

“…Eight patients with severe emphysema entered a pilot study of unilateral volume reduction by endobronchial valve insertion. Five patients had emphysema judged…”
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Respiratory muscle strength and ventilatory failure in amyotrophic lateral sclerosis by Lyall, R. A., Donaldson, N., Polkey, M. I., Leigh, P. N., Moxham, J.

“…Although ventilatory failure is the most common cause of death in amyotrophic lateral sclerosis (ALS) and measurement of respiratory muscle strength (RMS) has…”
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The effect of noninvasive ventilation on ALS patients and their caregivers by MUSTFA, N, WALSH, E, BRYANT, V, LYALL, R. A, ADDINGTON-HALL, J, GOLDSTEIN, L. H, DONALDSON, N, POLKEY, M. I, MOXHAM, J, LEIGH, P. N

“…Noninvasive ventilation (NIV) reduces mortality and improves some aspects of quality of life (QoL) in ALS. However, concerns remain that progressive disability…”
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High pressure versus high intensity noninvasive ventilation in stable hypercapnic chronic obstructive pulmonary disease: a randomized crossover trial by Murphy, Patrick B, Brignall, Kate, Moxham, John, Polkey, Michael I, Davidson, A Craig, Hart, Nicholas

“…High-intensity (high-pressure and high backup rate) noninvasive ventilation has recently been advocated for the management of stable hypercapnic chronic…”
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Magnetic stimulation for the measurement of respiratory and skeletal muscle function by Man, W.D-C, Moxham, J, Polkey, M.I

“…Respiratory and skeletal muscle function is of interest in many areas of pulmonary and critical care medicine. The capacity of the respiratory muscle pump to…”
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Klotho and smoking – An interplay influencing the skeletal muscle function deficits that occur in COPD by Patel, M.S, Donaldson, A.V, Lewis, A, Natanek, S.A, Lee, J.Y, Andersson, Y.M, Haji, G, Jackson, S.G, Bolognese, B.J, Foley, J.P, Podolin, P.L, Bruijnzeel, P.L.B, Hart, N, Hopkinson, N.S, Man, W.D.-C, Kemp, P.R, Polkey, M.I

“…Abstract Background Klotho is an ‘anti-ageing’ hormone and transmembrane protein; Klotho deficient mice develop a similar ageing phenotype to smokers including…”
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A novel in-ear sensor to determine sleep latency during the Multiple Sleep Latency Test in healthy adults with and without sleep restriction by Alqurashi, Yousef D, Nakamura, Takashi, Goverdovsky, Valentin, Moss, James, Polkey, Michael I, Mandic, Danilo P, Morrell, Mary J

“…Detecting sleep latency during the Multiple Sleep Latency Test (MSLT) using electroencephalogram (scalp-EEG) is time-consuming. The aim of this study was to…”
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Mechanisms of improvement of respiratory failure in patients with restrictive thoracic disease treated with non-invasive ventilation by Nickol, A H, Hart, N, Hopkinson, N S, Moxham, J, Simonds, A, Polkey, M I

“…Background: Nocturnal non-invasive ventilation (NIV) is an effective treatment for hypercapnic respiratory failure in patients with restrictive thoracic…”
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A novel technique for nonvolitional assessment of quadriceps muscle endurance in humans by Swallow, E. B, Gosker, H. R, Ward, K. A, Moore, A. J, Dayer, M. J, Hopkinson, N. S, Schols, A. M. W. J, Moxham, J, Polkey, M. I

“…1 Respiratory Muscle Laboratory, Royal Brompton Hospital, London, United Kingdom; 2 Department of Respiratory Medicine, University of Maastricht, Maastricht,…”
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Exercise response to oxygen supplementation is not associated with survival in hypoxemic patients with obstructive lung disease by Sadaka, Ahmed S, Montgomery, Andrew J, Mourad, Sahar M, Polkey, Michael I, Hopkinson, Nicholas S

“…Hypoxemia is associated with more severe lung disease and worse outcomes. In some patients with chronic obstructive lung diseases who desaturate on exertion,…”
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