Search Results - "Polizzotto, Mark N."
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Kaposi Sarcoma–Associated Herpesvirus-Associated Malignancies: Epidemiology, Pathogenesis, and Advances in Treatment
Published in Seminars in oncology (01-04-2015)“…Kaposi sarcoma associated herpesvirus (KSHV), a γ2-herpesvirus, also known as human herpesvirus-8, is the etiologic agent of three virally associated tumors:…”
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Viral, immunologic, and clinical features of primary effusion lymphoma
Published in Blood (18-04-2019)“…Primary effusion lymphoma (PEL) is an aggressive HIV-associated lymphoma with a relatively poor prognosis in the era of effective HIV therapy. Kaposi sarcoma…”
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Prevalence and incidence of hypertension in a heavily treatment-experienced cohort of people living with HIV in Uganda
Published in PloS one (17-02-2023)“…The effect of long-term exposure to antiretroviral therapy (ART) on hypertension in sub-Saharan Africa remains unclear. We aimed to determine the prevalence…”
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Monoclonal antibody levels and protection from COVID-19
Published in Nature communications (28-07-2023)“…Multiple monoclonal antibodies have been shown to be effective for both prophylaxis and therapy for SARS-CoV-2 infection. Here we aggregate data from…”
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Clinical Manifestations of Kaposi Sarcoma Herpesvirus Lytic Activation: Multicentric Castleman Disease (KSHV-MCD) and the KSHV Inflammatory Cytokine Syndrome
Published in Frontiers in microbiology (2012)“…Soon after the discovery of Kaposi sarcoma (KS)-associated herpesvirus (KSHV), it was appreciated that this virus was associated with most cases of…”
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Human and viral interleukin-6 and other cytokines in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease
Published in Blood (19-12-2013)“…Kaposi sarcoma herpesvirus (KSHV)-associated multicentric Castleman disease (MCD) is a polyclonal B-cell lymphoproliferative disorder. Human (h) IL-6 and a…”
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Outcomes of human immunodeficiency virus‐associated Burkitt lymphoma and diffuse large B‐cell lymphoma treated in Australia: A report from the Australasian Lymphoma Alliance
Published in British journal of haematology (01-06-2023)“…Summary Antiretroviral therapy (ART) has improved outcomes for human immunodeficiency virus‐associated non‐Hodgkin lymphoma (HIV‐NHL). This is an analysis of…”
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Kaposi Sarcoma Herpesvirus Promotes Endothelial-to-Mesenchymal Transition through Notch-Dependent Signaling
Published in Cancer research (Chicago, Ill.) (01-03-2012)“…Endothelial-to-mesenchymal transition (EndMT) is now widely considered a pivotal contributor to cancer progression. In this study, we show that the Kaposi's…”
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Sequencing of Kaposi's Sarcoma Herpesvirus (KSHV) genomes from persons of diverse ethnicities and provenances with KSHV-associated diseases demonstrate multiple infections, novel polymorphisms, and low intra-host variance
Published in PLoS pathogens (01-07-2024)“…Recently published near full-length KSHV genomes from a Cameroon Kaposi sarcoma case-control study showed strong evidence of viral recombination and mixed…”
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High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: a pilot study of virus-activated cytotoxic therapy
Published in Blood (30-06-2011)“…Kaposi sarcoma herpesvirus (KSHV)–associated multicentric Castleman disease (MCD) is a lymphoproliferative disorder most commonly observed in HIV-infected…”
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Clinical and laboratory features of COVID-19 illness and outcomes in immunocompromised individuals during the first pandemic wave in Sydney, Australia
Published in PloS one (01-11-2023)“…People with immunocompromising conditions are at increased risk of SARS-CoV-2 infection and mortality, however early in the pandemic it was challenging to…”
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Phase II Study of Bevacizumab in Patients With HIV-Associated Kaposi's Sarcoma Receiving Antiretroviral Therapy
Published in Journal of clinical oncology (01-05-2012)“…Alternatives to cytotoxic agents are desirable for patients with HIV-associated Kaposi's sarcoma (KS). Vascular endothelial growth factor-A (VEGF-A)…”
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Heterogeneity and breadth of host antibody response to KSHV infection demonstrated by systematic analysis of the KSHV proteome
Published in PLoS pathogens (01-03-2014)“…The Kaposi sarcoma associated herpesvirus (KSHV) genome encodes more than 85 open reading frames (ORFs). Serological evaluation of KSHV infection now generally…”
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Induction of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral Interleukin-6 by X-Box Binding Protein 1
Published in Journal of virology (01-01-2016)“…Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent for Kaposi sarcoma (KS), primary effusion lymphoma (PEL), and a subset of multicentric…”
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The Health Gym: synthetic health-related datasets for the development of reinforcement learning algorithms
Published in Scientific data (11-11-2022)“…In recent years, the machine learning research community has benefited tremendously from the availability of openly accessible benchmark datasets. Clinical…”
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HIV treatment regimens and adherence to national guidelines in Australia: an analysis of dispensing data from the Australian pharmaceutical benefits scheme
Published in BMC public health (03-01-2019)“…Treatment guidelines for antiretroviral therapy (ART) have evolved to emphasize newer regimens that address ageing-related comorbidities. Using national…”
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Deconstructing the liquid architecture of human herpesvirus 8 diseases
Published in British journal of haematology (01-02-2023)“…Human herpesvirus 8 (HHV‐8), also called Kaposi sarcoma herspesvirus (KSHV), causes several human tumours, which may be associated with systemic inflammation…”
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Corrigendum: Clinical manifestations of Kaposi sarcoma herpesvirus lytic activation: multicentric Castleman disease (KSHV-MCD) and the KSHV inflammatory cytokine syndrome
Published in Frontiers in microbiology (21-08-2017)“…[This corrects the article on p. 73 in vol. 3, PMID: 22403576.]…”
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Human herpes virus 8-related illness: still with us
Published in AIDS (London) (15-11-2022)Get full text
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Bisphosphonate‐associated osteonecrosis of the auditory canal
Published in British journal of haematology (01-01-2006)Get full text
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