Search Results - "Poliero, Luca"

Comprehensive genome profiling by next generation sequencing of circulating tumor DNA in solid tumors: a single academic institution experience by Caputo, Vincenza, De Falco, Vincenzo, Ventriglia, Anna, Famiglietti, Vincenzo, Martinelli, Erika, Morgillo, Floriana, Martini, Giulia, Corte, Carminia Maria Della, Ciardiello, Davide, Poliero, Luca, De Vita, Ferdinando, Orditura, Michele, Fasano, Morena, Franco, Renato, Caraglia, Michele, Avitabile, Arianna, Scalamogna, Roberto, Marchi, Beatrice, Ciardiello, Fortunato, Troiani, Teresa, Napolitano, Stefania

“…Background: Recently, new evidence of the next-generation sequencing (NGS) liquid biopsy utility in clinical practice has been developed. This assay is…”
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Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer by Vitiello, Pietro Paolo, Martini, Giulia, Mele, Luigi, Giunta, Emilio Francesco, De Falco, Vincenzo, Ciardiello, Davide, Belli, Valentina, Cardone, Claudia, Matrone, Nunzia, Poliero, Luca, Tirino, Virginia, Napolitano, Stefania, Della Corte, Carminia, Selvaggi, Francesco, Papaccio, Gianpaolo, Troiani, Teresa, Morgillo, Floriana, Desiderio, Vincenzo, Ciardiello, Fortunato, Martinelli, Erika

“…Despite the advancements in new therapies for colorectal cancer (CRC), chemotherapy still constitutes the mainstay of the medical treatment. For this reason,…”
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How I treat anal squamous cell carcinoma by Martini, Giulia, Arrichiello, Gianluca, Borrelli, Carola, Poliero, Luca, Martinelli, Erika

“…Squamous cell carcinoma of the anus (SCCA) is a rising health issue, strongly related to other relevant medical conditions such as (HIV) and human…”
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Dual inhibition of TGFβ and AXL as a novel therapy for human colorectal adenocarcinoma with mesenchymal phenotype by Ciardiello, Davide, Blauensteiner, Bernadette, Matrone, Nunzia, Belli, Valentina, Mohr, Thomas, Vitiello, Pietro Paolo, Martini, Giulia, Poliero, Luca, Cardone, Claudia, Napolitano, Stefania, De Falco, Vincenzo, Giunta, Emilio Francesco, Ciaramella, Vincenza, Corte, Carminia della, Barra, Giusi, Selvaggi, Francesco, Franco, Renato, Marino, Federica Zito, Cuomo, Antonio, Morgillo, Floriana, Troiani, Teresa, Sibilia, Maria, Ciardiello, Fortunato, Martinelli, Erika

“…A subset of colorectal cancer (CRC) with a mesenchymal phenotype (CMS4) displays an aggressive disease, with an increased risk of recurrence after surgery,…”
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Immunotherapy in colorectal cancer: is the long-awaited revolution finally happening? by Arrichiello, Gianluca, Poliero, Luca, Borrelli, Carola, Paragliola, Fernando, Nacca, Valeria, Napolitano, Stefania, Corte, Carminia Maria Della, Martini, Giulia, Martinelli, Erika

“…Immunotherapy has recently become a major treatment modality for several types of solid tumours, achieving remarkable and long-lasting remissions. In…”
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Overcoming immune-resistance in laryngeal cancer: a case report of the abscopal effect and nivolumab beyond progression by Marco, De Felice, Gianluca, Arrichiello, Mariagrazia, Tammaro, Luca, e Poliero

“…The abscopal effect is defined as the systemic regression of distant neoplastic lesions induced by localized treatment. Although the first case reports date…”
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Clinical Practice Use of Liquid Biopsy to Identify RAS/BRAF Mutations in Patients with Metastatic Colorectal Cancer (mCRC): A Single Institution Experience by Vitiello, Pietro Paolo, De Falco, Vincenzo, Giunta, Emilio Francesco, Ciardiello, Davide, Cardone, Claudia, Vitale, Pasquale, Zanaletti, Nicoletta, Borrelli, Carola, Poliero, Luca, Terminiello, Marinella, Arrichiello, Gianluca, Caputo, Vincenza, Famiglietti, Vincenzo, Mattera Iacono, Valentina, Marrone, Francesca, Di Liello, Alessandra, Martini, Giulia, Napolitano, Stefania, Caraglia, Michele, Lombardi, Angela, Franco, Renato, De Vita, Ferdinando, Morgillo, Floriana, Troiani, Teresa, Ciardiello, Fortunato, Martinelli, Erika

“…Tumor heterogeneity represents a possible cause of error in detecting predictive genetic alterations on tumor tissue and can be overcome by testing alterations…”
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Abstract 295: Synergism between oxaliplatin or irinotecan with the PARP inhibitor niraparib in a preclinical model of KRAS/BRAF mutated colorectal cancer is associated with MSI status by Vitiello, Pietro Paolo, Ciardiello, Davide, Cardone, Claudia, Martini, Giulia, Belli, Valentina, Matrone, Nunzia, Poliero, Luca, Borrelli, Carola, Vitale, Pasquale, Zanaletti, Nicoletta, Troiani, Teresa, Melisi, Davide, Ciardiello, Fortunato, Martinelli, Erika

“…DNA damage response (DDR) is crucial in a variety of tumors and several new drugs that interfere with this mechanism are already available or in advanced…”
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Abstract 2627: Inhibition of TGFβ in colorectal cancer cells is associated with a compensatory activation of AXL and p38 MAPK signaling pathways by Ciardiello, Davide, Vitiello, Pietro Paolo, Matrone, Nunzia, Belli, Valentina, Cardone, Claudia, Poliero, Luca, Borrelli, Carola, Arrichiello, Gianluca, Martini, Giulia, Ciaramella, Vincenza, Barra, Giusi, Morgillo, Floriana, Troiani, Teresa, Melisi, Davide, Ciardiello, Fortunato, Martinelli, Erika

“…According to the consensus molecular subtypes (CMS), almost 23% of human colorectal cancer (CRC) are classified in the CMS4 group, characterized by a…”
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Feasibility of next-generation sequencing in clinical practice: results of a pilot study in the Department of Precision Medicine at the University of Campania ‘Luigi Vanvitelli’ by De Falco, Vincenzo, Poliero, Luca, Vitello, Pietro Paolo, Ciardiello, Davide, Vitale, Pasquale, Zanaletti, Nicoletta, Giunta, Emilio Francesco, Terminiello, Marinella, Caputo, Vincenza, Carlino, Francesca, Di Liello, Raimondo, Ventriglia, Anna, Famiglietti, Vincenzo, Martinelli, Erika, Morgillo, Floriana, Orditura, Michele, De Vita, Ferdinando, Fasano, Morena, Napolitano, Stefania, Martini, Giulia, Della Corte, Carminia Maria, Franco, Renato, Altucci, Lucia, Ciardiello, Fortunato, Troiani, Teresa

“…BackgroundThe emerging role of next-generation sequencing (NGS) targeted panels is revolutionising our approach to cancer patients, providing information on…”
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