Search Results - "Poliakova, Daniela Kostanova"
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Enhancers of the PAIR4 regulatory module promote distal VH gene recombination at the Igh locus
Published in The EMBO journal (01-08-2023)“…While extended loop extrusion across the entire Igh locus controls V H ‐DJ H recombination, local regulatory sequences, such as the PAIR elements, may also…”
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The PAX5‐JAK2 translocation acts as dual‐hit mutation that promotes aggressive B‐cell leukemia via nuclear STAT5 activation
Published in The EMBO journal (04-04-2022)“…While PAX5 is an important tumor suppressor gene in B‐cell acute lymphoblastic leukemia (B‐ALL), it is also involved in oncogenic translocations coding for…”
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Essential role for the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells
Published in Nature immunology (01-04-2017)“…B-1a B cells are a distinct subset of mature B cells that provide innate-like protection against pathogens. Busslinger and colleagues identify the…”
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Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development
Published in The Journal of experimental medicine (27-06-2016)“…E2A is an essential regulator of early B cell development. Here, we have demonstrated that E2A together with E2-2 controlled germinal center (GC) B cell and…”
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Enhancers of the PAIR4 regulatory module promote distal V H gene recombination at the Igh locus
Published in The EMBO journal (01-08-2023)“…While extended loop extrusion across the entire Igh locus controls V -DJ recombination, local regulatory sequences, such as the PAIR elements, may also…”
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The Xbp1-regulated transcription factor Mist1 restricts antibody secretion by restraining Blimp1 expression in plasma cells
Published in Frontiers in immunology (21-12-2022)“…Antibody secretion by plasma cells provides acute and long-term protection against pathogens. The high secretion potential of plasma cells depends on the…”
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Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion
Published in Nature (London) (06-08-2020)“…Nuclear processes, such as V(D)J recombination, are orchestrated by the three-dimensional organization of chromosomes at multiple levels, including…”
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β-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis
Published in Development (Cambridge) (15-10-2016)“…Trabecular bone formation is the last step in endochondral ossification. This remodeling process of cartilage into bone involves blood vessel invasion and…”
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Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development
Published in The Journal of cell biology (20-06-2016)Get full text
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Mutation in the β subunit of F₁ ATPase allows Kluyveromyces lactis to survive the disruption of the KlPGS1 gene
Published in FEMS yeast research (01-09-2010)“…The petite-negative yeast Kluyveromyces lactis does not tolerate the loss of phosphatidylglycerol (PG). We demonstrate that the lethality of PG loss is…”
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Lactate utilization in mitochondria prevents Bax cytotoxicity in yeast Kluyveromyces lactis
Published in FEBS letters (26-09-2005)“…In a search for the physiological conditions able to suppress the disruption of electron transport through the inner mitochondrial membrane induced by Bax, we…”
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Mutation in the beta subunit of F ATPase allows Kluyveromyces lactis to survive the disruption of the KlPGS1 gene
Published in FEMS yeast research (01-09-2010)“…The petite-negative yeast Kluyveromyces lactis does not tolerate the loss of phosphatidylglycerol (PG). We demonstrate that the lethality of PG loss is…”
Get full text
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