Search Results - "Poliachik, Sandra"

MRI-informed muscle biopsies correlate MRI with pathology and DUX4 target gene expression in FSHD by Wang, Leo H, Friedman, Seth D, Shaw, Dennis, Snider, Lauren, Wong, Chao-Jen, Budech, Chris B, Poliachik, Sandra L, Gove, Nancy E, Lewis, Leann M, Campbell, Amy E, Lemmers, Richard J F L, Maarel, Silvère M, Tapscott, Stephen J, Tawil, Rabi N

“…Abstract Facioscapulohumeral muscular dystrophy (FSHD) is a common, dominantly inherited disease caused by the epigenetic de-repression of the DUX4 gene, a…”
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MRI change metrics of facioscapulohumeral muscular dystrophy: Stir and T1 by Ferguson, Mark R., Poliachik, Sandra L., Budech, Christopher B., Gove, Nancy E., Carter, Gregory T., Wang, Leo H., Miller, Daniel G., Shaw, Dennis W.W., Friedman, Seth D.

“…ABSTRACT Introduction: MRI evaluation in facioscapulohumeral muscular dystrophy (FSHD) demonstrates fatty replacement and inflammation/edema in muscle. Our…”
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Laser Ablation Therapy for Pediatric Patients with Intracranial Lesions in Eloquent Areas by Kuo, Chao-Hung, Feroze, Abdullah H., Poliachik, Sandra L., Hauptman, Jason S., Novotny, Edward J., Ojemann, Jeffrey G.

“…Laser interstitial thermal therapy (LITT) is an alternative, less-invasive, and, in some circumstances, effective treatment for patients with intracranial…”
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Geometric morphometrics reveal altered corpus callosum shape in pyridoxine-dependent epilepsy by Oesch, Gabriela, Maga, A Murat, Friedman, Seth D, Poliachik, Sandra L, Budech, Christopher B, Wright, Jason N, Bok, Levinus A, Gospe, Sidney M

“…OBJECTIVETo evaluate the features and maturational changes in overall callosal shape in patients with pyridoxine-dependent epilepsy (PDE). METHODSMeasurements…”
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Transient muscle paralysis disrupts bone homeostasis by rapid degradation of bone morphology by Poliachik, Sandra L, Bain, Steven D, Threet, DeWayne, Huber, Philippe, Gross, Ted S

“…Abstract We have previously shown that transient paralysis of murine hindlimb muscles causes profound degradation of both trabecular and cortical bone in the…”
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A cross sectional study of two independent cohorts identifies serum biomarkers for facioscapulohumeral muscular dystrophy (FSHD) by Petek, Lisa M, Rickard, Amanda M, Budech, Christopher, Poliachik, Sandra L, Shaw, Dennis, Ferguson, Mark R, Tawil, Rabi, Friedman, Seth D, Miller, Daniel G

“…Highlights • Four serum biomarkers that correlate with FSHD disease severity are identified. • FSHD serum biomarkers were validated in a separate patient…”
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Preservation of electrophysiological functional connectivity after partial corpus callosotomy: case report by Casimo, Kaitlyn, Grassia, Fabio, Poliachik, Sandra L, Novotny, Edward, Poliakov, Andrew, Ojemann, Jeffrey G

“…Prior studies of functional connectivity following callosotomy have disagreed in the observed effects on interhemispheric functional connectivity. These…”
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Longitudinal features of STIR bright signal in FSHD by Friedman, Seth D, Poliachik, Sandra L, Otto, Randolph K, Carter, Gregory T, Budech, Christopher B, Bird, Thomas D, Miller, Daniel G, Shaw, Dennis W W

“…Magnetic resonance imaging of muscle shows short tau-inversion recovery (STIR) brightness in autosomal dominant facioscapulohumeral muscular dystrophy (FSHD1)…”
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Quantitative MRI reveals decelerated fatty infiltration in muscles of active FSHD patients by Ferguson, Mark R, Poliachik, Sandra L, Shaffer, Michele L, Friedman, Seth D

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Control of bone resorption in mice by Schnurri-3 by Wein, Marc N, Jones, Dallas C, Shim, Jae-Hyuck, Aliprantis, Antonios O, Sulyanto, Rosalyn, Lazarevic, Vanja, Poliachik, Sandra L, Gross, Ted S, Glimcher, Laurie H

“…Mice lacking the large zinc finger protein Schnurri-3 (Shn3) display increased bone mass, in part, attributable to augmented osteoblastic bone formation. Here,…”
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Transient muscle paralysis degrades bone via rapid osteoclastogenesis by Aliprantis, Antonios O., Stolina, Marina, Kostenuik, Paul J., Poliachik, Sandra L., Warner, Sarah E., Bain, Steven D., Gross, Ted S.

“…A unilateral injection of botulinum toxin A (BTxA) in the calf induces paralysis and profound loss of ipsalateral trabecular bone within days. However, the…”
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Metaphyseal and diaphyseal bone loss in the tibia following transient muscle paralysis are spatiotemporally distinct resorption events by Ausk, Brandon J, Huber, Philippe, Srinivasan, Sundar, Bain, Steven D, Kwon, Ronald Y, McNamara, Erin A, Poliachik, Sandra L, Sybrowsky, Christian L, Gross, Ted S

“…Abstract When the skeleton is catabolically challenged, there is great variability in the timing and extent of bone resorption observed at cancellous and…”
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Rest-inserted loading rapidly amplifies the response of bone to small increases in strain and load cycles by Srinivasan, Sundar, Ausk, Brandon J, Poliachik, Sandra L, Warner, Sarah E, Richardson, Thomas S, Gross, Ted S

“…Departments of 1 Orthopaedics and Sports Medicine and 2 Statistics, University of Washington, Seattle, Washington Submitted 2 May 2006 ; accepted in final form…”
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Cortical bone resorption following muscle paralysis is spatially heterogeneous by Ausk, Brandon J, Huber, Philippe, Poliachik, Sandra L, Bain, Steven D, Srinivasan, Sundar, Gross, Ted S

“…Abstract Mechanical loading of the skeleton, as induced by muscle function during activity, plays a critical role in maintaining bone homeostasis. It is not…”
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The magnetic resonance imaging spectrum of facioscapulohumeral muscular dystrophy by Friedman, Seth D., Poliachik, Sandra L., Carter, Gregory T., Budech, Christopher B., Bird, Thomas D., Shaw, Dennis W.W.

“…Introduction: Facioscapulohumeral muscular dystrophy (FSHD) is associated with a repeat contraction in the D4Z4 gene locus on chromosome 4q35. We used a…”
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Muscle-fat magnetic resonance imaging: Applications by Friedman, Seth D., Poliachik, Sandra L., Carter, Gregory T.

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Callosal alterations in pyridoxine‐dependent epilepsy by Friedman, Seth D, Ishak, Gisele E, Poliachik, Sandra L, Poliakov, Andrew V, Otto, Randolph K, Shaw, Dennis W W, Willemsen, Michèl A, Bok, Levinus A, Gospe, Sidney M

“…Aim While there have been isolated reports of callosal morphology differences in pyridoxine‐dependent epilepsy (PDE), a rare autosomal disorder caused by…”
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Changes in resting-state connectivity in pediatric temporal lobe epilepsy by Grassia, Fabio, Poliakov, Andrew V, Poliachik, Sandra L, Casimo, Kaitlyn, Friedman, Seth D, Shurtleff, Hillary, Giussani, Carlo, Novotny, Edward J, Ojemann, Jeffrey G, Hauptman, Jason S

“…OBJECTIVE Functional connectivity magnetic resonance imaging (fcMRI) is a form of fMRI that allows for analysis of blood oxygen level-dependent signal changes…”
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Corpus Callosum Diffusion and Connectivity Features in High Functioning Subjects With Pyridoxine-Dependent Epilepsy by Poliachik, Sandra L., PhD, Friedman, Seth D., PhD, Poliakov, Andrew V., PhD, Budech, Christopher B., BA, Ishak, Gisele E., MD, Shaw, Dennis W.W., MD, Gospe, Sidney M., MD, PhD

“…Abstract Background In this observational study, white matter structure, functional magnetic resonance imaging (fMRI) task-based responses, and functional…”
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RAD001 (Everolimus) inhibits growth of prostate cancer in the bone and the inhibitory effects are increased by combination with docetaxel and zoledronic acid by Morgan, Todd M., Pitts, Tiffany E.M., Gross, Ted S., Poliachik, Sandra L., Vessella, Robert L., Corey, Eva

“…Introduction mTOR activity is increased in advanced prostate cancer (CaP) as a result of a high rate of PTEN mutations. RAD001 (Everolimus) is a new orally…”
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