Search Results - "Poli, V"
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STAT3 can serve as a hit in the process of malignant transformation of primary cells
Published in Cell death and differentiation (01-08-2012)“…The transcription factor signal transducer and activator of transcription 3 (STAT3) acts downstream of many pro-oncogenic signals, including cytokines, growth…”
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A Cathepsin D-Cleaved 16 kDa Form of Prolactin Mediates Postpartum Cardiomyopathy
Published in Cell (09-02-2007)“…Postpartum cardiomyopathy (PPCM) is a disease of unknown etiology and exposes women to high risk of mortality after delivery. Here, we show that female mice…”
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Diazoxide postconditioning induces mitochondrial protein S-Nitrosylation and a redox-sensitive mitochondrial phosphorylation/translocation of RISK elements: no role for SAFE
Published in Basic research in cardiology (01-09-2013)“…Postconditioning (PostC) can be obtained either with brief cycles of ischemia/reperfusion (I-PostC) or with a direct targeting of mitochondria with Diazoxide…”
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Identification of STAT3 as a specific substrate of breast tumor kinase
Published in Oncogene (10-08-2006)“…Breast tumor kinase (Brk) is a non-receptor tyrosine kinase distantly related to the Src family kinase. It is expressed in more than 60% of breast tumors, but…”
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P399: UNRAVELING THE TUMOR SUPPRESSIVE ROLE OF STAT3Β IN ACUTE MYELOID LEUKEMIA
Published in HemaSphere (23-06-2022)Get full text
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Essential Role of STAT3 in the Control of the Acute-Phase Response as Revealed by Inducible Gene Activation in the Liver
Published in Molecular and Cellular Biology (01-03-2001)“…ERRATUM ( vol. 21 , p. 2967 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious…”
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IL-6, but not IFN-γ, triggers apoptosis and inhibits in vivo growth of human malignant T cells on STAT3 silencing
Published in Leukemia (01-11-2009)“…STAT1 and STAT3 are the main mediators of the signaling of interferons (IFNs) and of gp130 cytokines, respectively. Neoplastic T lymphocytes frequently become…”
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Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipopolysaccharide or IL-1 beta: a study on IL-6-deficient mice
Published in The Journal of experimental medicine (01-01-1996)“…Interleukin (IL)-6, IL-1 beta, and tumor necrosis factor alpha (TNF-alpha) are considered to act as endogenous pyrogens. Because of the complex pattern of…”
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Role of IL-6 in cytokine-induced sickness behavior: a study with IL-6 deficient mice
Published in Physiology & behavior (01-08-2000)“…Interleukin-6 (IL-6) is synthesized and released in response to the cytokine inducer lipopolysaccharide (LPS) and IL-1, and acts as an endogenous pyrogen…”
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P381 THE ROLE OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 (STAT3) IN CHOLESTASIS AND BILE ACID (BA) SYNTHESIS
Published in Journal of hepatology (01-04-2014)Get full text
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PO-298 MYC favours the onset of tumour initiating cells by inducing epigenetic reprogramming of mammary epithelial cells towards a stem cell-like state
Published in ESMO open (01-07-2018)“…IntroductionBreast cancer consists of highly heterogenous tumours whose cell of origin resulted difficult to be defined. Recent findings highlighted the…”
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PO-237 The pro-oncogenic transcription factor STAT3 regulates Ca2 +release and apoptosis from the endoplasmic reticulum via interaction with the Ca2 +CHANNEL IP3R3
Published in ESMO open (01-07-2018)“…IntroductionSignal Transducer and Activator of Transcription (STAT) 3 is an oncogenic transcription factor found constitutively activated in several tumours,…”
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CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy
Published in The Journal of clinical investigation (01-09-1998)“…After two-thirds hepatectomy, normally quiescent liver cells are stimulated to reenter the cell cycle and proliferate to restore the original liver mass. The…”
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TEVAR for Iatrogenic Injury of the Distal Aortic Arch after Pacemaker Implantation
Published in European journal of vascular and endovascular surgery (01-08-2013)Get full text
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Interleukin‐6 deficient mice are protected from bone loss caused by estrogen depletion
Published in The EMBO journal (01-03-1994)“…Interleukin‐6 (IL‐6) is a multifunctional cytokine whose circulating levels are under physiological conditions below detection, but whose production is rapidly…”
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Defective inflammatory response in interleukin 6-deficient mice
Published in The Journal of experimental medicine (01-10-1994)“…Systemic and localized inflammation elicit a number of host responses which include fever, cachexia, hypoglycemia, and major changes in the concentration of…”
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7018 POSTER NFkB Activity Modulates the Oncogenic Potential of Stat3 in Prostate Cancer Development
Published in European journal of cancer (1990) (2011)Get full text
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Endogenous leukemia inhibitory factor attenuates endotoxin response
Published in Laboratory investigation (01-02-2005)“…Leukemia inhibitory factor (LIF) is induced in inflammation and likely plays a regulatory role. Using LIF-deficient mice (LIF−/−), we report here that…”
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Intercomparison of two nowcasting methods: preliminary analysis
Published in Meteorology and atmospheric physics (01-10-2008)“…Summary With term nowcasting is intended the description of a weather situation and its consequent extrapolation ahead in the future for few hours. This work…”
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