Search Results - "Poli, Aurélie"

PARK7/DJ-1 in microglia: implications in Parkinson's disease and relevance as a therapeutic target by Lind-Holm Mogensen, Frida, Scafidi, Andrea, Poli, Aurélie, Michelucci, Alessandro

“…Microglia are the immune effector cells of the brain playing critical roles in immune surveillance and neuroprotection in healthy conditions, while they can…”
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Revisiting the Functional Impact of NK Cells by Poli, Aurélie, Michel, Tatiana, Patil, Neha, Zimmer, Jacques

“…Immune responses are critical for the maintenance of homeostasis but can also upset the equilibrium, depending on the context and magnitude of the response…”
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Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia by Baginska, Joanna, Viry, Elodie, Berchem, Guy, Poli, Aurélie, Noman, Muhammad Zaeem, van Moer, Kris, Medves, Sandrine, Zimmer, Jacques, Oudin, Anaïs, Niclou, Simone P., Bleackley, R. Chris, Goping, Ing Swie, Chouaib, Salem, Janji, Bassam

“…Recent studies demonstrated that autophagy is an important regulator of innate immune response. However, the mechanism by which autophagy regulates natural…”
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Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level by Kmiecik, Justyna, Poli, Aurélie, Brons, Nicolaas H.C, Waha, Andreas, Eide, Geir Egil, Enger, Per Øyvind, Zimmer, Jacques, Chekenya, Martha

“…Abstract We characterized GBM patients' tumor and systemic immune contexture with aim to reveal the mechanisms of immunological escape, their impact on patient…”
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CpG Adjuvant in Allergen-Specific Immunotherapy: Finding the Sweet Spot for the Induction of Immune Tolerance by Montamat, Guillem, Leonard, Cathy, Poli, Aurélie, Klimek, Ludger, Ollert, Markus

“…Prevalence and incidence of IgE-mediated allergic diseases have increased over the past years in developed and developing countries. Allergen-specific…”
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NK cells in central nervous system disorders by Poli, Aurélie, Kmiecik, Justyna, Domingues, Olivia, Hentges, François, Bléry, Mathieu, Chekenya, Martha, Boucraut, José, Zimmer, Jacques

“…NK cells are important players in immunity against pathogens and neoplasms. As a component of the innate immune system, they are one of the first effectors on…”
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Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus by Perez-Bercoff, Danielle, Laude, Hélène, Lemaire, Morgane, Hunewald, Oliver, Thiers, Valérie, Vignuzzi, Marco, Blanc, Hervé, Poli, Aurélie, Amoura, Zahir, Caval, Vincent, Suspène, Rodolphe, Hafezi, François, Mathian, Alexis, Vartanian, Jean-Pierre, Wain-Hobson, Simon

“…APOBEC3 (A3) enzymes are best known for their role as antiviral restriction factors and as mutagens in cancer. Although four of them, A3A, A3B, A3F and A3G,…”
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Elucidating tumour‐associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency by Pires‐Afonso, Yolanda, Muller, Arnaud, Grzyb, Kamil, Oudin, Anaïs, Yabo, Yahaya A., Sousa, Carole, Scafidi, Andrea, Poli, Aurélie, Cosma, Antonio, Halder, Rashi, Coowar, Djalil, Golebiewska, Anna, Skupin, Alexander, Niclou, Simone P., Michelucci, Alessandro

“…In glioblastoma (GBM), tumour‐associated microglia/macrophages (TAMs) represent the major cell type of the stromal compartment and contribute to tumour immune…”
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Human leukocyte antigen class I deficiencies by Michel, Tatiana, Poli, Aurélie, Zimmer, Jacques

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PARK7/DJ-1 deficiency impairs microglial activation in response to LPS-induced inflammation by Lind-Holm Mogensen, Frida, Sousa, Carole, Ameli, Corrado, Badanjak, Katja, Pereira, Sandro L, Muller, Arnaud, Kaoma, Tony, Coowar, Djalil, Scafidi, Andrea, Poovathingal, Suresh K, Tziortziou, Maria, Antony, Paul M A, Nicot, Nathalie, Ginolhac, Aurélien, Vogt Weisenhorn, Daniela M, Wurst, Wolfgang, Poli, Aurélie, Nazarov, Petr V, Skupin, Alexander, Grünewald, Anne, Michelucci, Alessandro

“…Specific microglia responses are thought to contribute to the development and progression of neurodegenerative diseases, including Parkinson's disease (PD)…”
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Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts by Yabo, Yahaya A, Moreno-Sanchez, Pilar M, Pires-Afonso, Yolanda, Kaoma, Tony, Nosirov, Bakhtiyor, Scafidi, Andrea, Ermini, Luca, Lipsa, Anuja, Oudin, Anaïs, Kyriakis, Dimitrios, Grzyb, Kamil, Poovathingal, Suresh K, Poli, Aurélie, Muller, Arnaud, Toth, Reka, Klink, Barbara, Berchem, Guy, Berthold, Christophe, Hertel, Frank, Mittelbronn, Michel, Heiland, Dieter H, Skupin, Alexander, Nazarov, Petr V, Niclou, Simone P, Michelucci, Alessandro, Golebiewska, Anna

“…A major contributing factor to glioblastoma (GBM) development and progression is its ability to evade the immune system by creating an immune-suppressive…”
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Allergic airway inflammation delays glioblastoma progression and reinvigorates systemic and local immunity in mice by Poli, Aurélie, Oudin, Anaïs, Muller, Arnaud, Salvato, Ilaria, Scafidi, Andrea, Hunewald, Oliver, Domingues, Olivia, Nazarov, Petr V., Puard, Vincent, Baus, Virginie, Azuaje, Francisco, Dittmar, Gunnar, Zimmer, Jacques, Michel, Tatiana, Michelucci, Alessandro, Niclou, Simone P., Ollert, Markus

“…Background Numerous patient‐based studies have highlighted the protective role of immunoglobulin E‐mediated allergic diseases on glioblastoma (GBM)…”
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Control of NK cell functions by CD4+CD25+ regulatory T cells by Ralainirina, Natacha, Poli, Aurélie, Michel, Tatiana, Poos, Linda, Andrès, Emmanuel, Hentges, François, Zimmer, Jacques

“…Regulatory T cells (Treg) are key players in the maintenance of peripheral tolerance. As a result of suppressive effects on CD4+ and CD8+ effector T cells,…”
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Granulocytes and mast cells in AllergoOncology—Bridging allergy to cancer: An EAACI position paper by Pascal, Mariona, Bax, Heather J., Bergmann, Christoph, Bianchini, Rodolfo, Castells, Mariana, Chauhan, Jitesh, De las Vecillas, Leticia, Hartmann, Karin, Álvarez, Elena Izquierdo, Jappe, Uta, Jimenez‐Rodriguez, Teodorikez‐Wilfox, Knol, Edward, Levi‐Schaffer, Francesca, Mayorga, Cristobalina, Poli, Aurélie, Redegeld, Frank, Santos, Alexandra F., Jensen‐Jarolim, Erika, Karagiannis, Sophia N.

“…Derived from the myeloid lineage, granulocytes, including basophils, eosinophils, and neutrophils, along with mast cells, play important, often disparate,…”
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Targeting glioblastoma with NK cells and mAb against NG2/CSPG4 prolongs animal survival by Poli, Aurélie, Wang, Jian, Domingues, Olivia, Planagumà, Jesús, Yan, Tao, Rygh, Cecilie Brekke, Skaftnesmo, Kai Ove, Thorsen, Frits, McCormack, Emmet, Hentges, François, Pedersen, Paal Henning, Zimmer, Jacques, Enger, Per Øyvind, Chekenya, Martha

“…Glioblastoma (GBM) is the most malignant brain tumor where patients' survival is only 14.6 months, despite multimodal therapy with debulking surgery,…”
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Targeting the ACOD1-itaconate axis stabilizes atherosclerotic plaques by Harber, Karl J., Neele, Annette E., van Roomen, Cindy PAA, Gijbels, Marion JJ, Beckers, Linda, Toom, Myrthe den, Schomakers, Bauke V., Heister, Daan AF, Willemsen, Lisa, Griffith, Guillermo R., de Goede, Kyra E., van Dierendonck, Xanthe AMH, Reiche, Myrthe E., Poli, Aurélie, L-H Mogensen, Frida, Michelucci, Alessandro, Verberk, Sanne GS, de Vries, Helga, van Weeghel, Michel, Van den Bossche, Jan, de Winther, Menno PJ

“…Inflammatory macrophages are key drivers of atherosclerosis that can induce rupture-prone vulnerable plaques. Skewing the plaque macrophage population towards…”
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Mouse lung and spleen natural killer cells have phenotypic and functional differences, in part influenced by macrophages by Michel, Tatiana, Poli, Aurélie, Domingues, Olivia, Mauffray, Marion, Thérésine, Maud, Brons, Nicolaas H C, Hentges, François, Zimmer, Jacques

“…NK cells are lymphocytes of the innate immune system which are a first line of defense against infections and tumor cells, in bone marrow and peripheral organs…”
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AllergoOncology: Biomarkers and refined classification for research in the allergy and glioma nexus—A joint EAACI‐EANO position paper by Turner, Michelle C., Radzikowska, Urszula, Ferastraoaru, Denisa E., Pascal, Mariona, Wesseling, Pieter, McCraw, Alexandra, Backes, Claudine, Bax, Heather J., Bergmann, Christoph, Bianchini, Rodolfo, Cari, Luigi, de las Vecillas, Leticia, Izquierdo, Elena, Lind‐Holm Mogensen, Frida, Michelucci, Alessandro, Nazarov, Petr V., Niclou, Simone P., Nocentini, Giuseppe, Ollert, Markus, Preusser, Matthias, Rohr‐Udilova, Nataliya, Scafidi, Andrea, Toth, Reka, Van Hemelrijck, Mieke, Weller, Michael, Jappe, Uta, Escribese, Maria M., Jensen‐Jarolim, Erika, Karagiannis, Sophia N., Poli, Aurélie

“…Epidemiological studies have explored the relationship between allergic diseases and cancer risk or prognosis in AllergoOncology. Some studies suggest an…”
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AllergoOncology: Danger signals in allergology and oncology: A European Academy of Allergy and Clinical Immunology (EAACI) Position Paper by Bergmann, Christoph, Poli, Aurélie, Agache, Ioana, Bianchini, Rodolfo, Bax, Heather J., Castells, Mariana, Crescioli, Silvia, Dombrowicz, David, Ferastraoaru, Denisa, Fiebiger, Edda, Gould, Hannah J., Hartmann, Karin, Izquierdo, Elena, Jordakieva, Galateja, Josephs, Debra H., Jutel, Marek, Levi‐Schaffer, Francesca, de las Vecillas, Leticia, Lotze, Michael T., Osborn, Gabriel, Pascal, Mariona, Redegeld, Frank, Rosenstreich, David, Roth‐Walter, Franziska, Schmidt‐Weber, Carsten, Shamji, Mohamed, Steveling, Esther H., Turner, Michelle C., Untersmayr, Eva, Jensen‐Jarolim, Erika, Karagiannis, Sophia N.

“…The immune system interacts with many nominal ‘danger’ signals, endogenous danger‐associated (DAMP), exogenous pathogen (PAMP) and allergen (AAMP)‐associated…”
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Metformin impacts the differentiation of mouse bone marrow cells into macrophages affecting tumour immunity by Scafidi, Andrea, Lind-Holm Mogensen, Frida, Campus, Eleonora, Pailas, Alexandros, Neumann, Katrin, Legrave, Nathalie, Bernardin, François, Pereira, Sandro L., Antony, Paul M.A., Nicot, Nathalie, Mittelbronn, Michel, Grünewald, Anne, Nazarov, Petr V., Poli, Aurélie, Van Dyck, Eric, Michelucci, Alessandro

“…Epidemiological studies suggest that metformin reduces the risk of developing several types of cancer, including gliomas, and improves the overall survival in…”
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