Search Results - "Polezhaev, F. I"

Recombinant cold-adapted attenuated influenza A vaccines for use in children: molecular genetic analysis of the cold-adapted donor and recombinants by GHENDON, Y. Z, POLEZHAEV, F. I, LISOVSKAYA, K. V, MEDVEDEVA, T. E, KLIMOV, A. I

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Recombinant cold-adapted attenuated influenza A vaccines for use in children: reactogenicity and antigenic activity of cold-adapted recombinants and analysis of isolates from the vaccinees by ALEXANDROVA, G. I, POLEZHAEV, F. I, GHENDON, Y. Z, BUDILOVSKY, G. N, GARMASHOVA, L. M, TOPURIA, N. A, EGOROV, A. Y, ROMEJKO-GURKO, Y. R, KOVAL, T. A, LISOVSKAYA, K. V, KLIMOV, A. I

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Analysis of Genome Composition and Reactogenicity of Recombinants of Cold-adapted and Virulent Virus Strains by Ghendon, Y. Z, Klimov, A. I, Alexandrova, G. I, Polezhaev, F. I

“…1 Moscow Research Institute for Viral Preparations, 15, 1st Dubrovskaya Str., Moscow 109088, U.S.S.R. and 2 Institute of Experimental Medicine, Leningrad,…”
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Class-specific antibody responses in school children vaccinated with an A/Brazil/11/78 (H1N1)-like recombinant influenza virus prepared from the A/Leningrad/134/57 paediatric cold-adapted donor strain by Slepushkin, A N, Patriarca, P A, Obrosova-Serova, N P, Harmon, M W, Kupryashina, L N, Cheshik, S G, Vartanyan, R B, Alexandrova, G I, Polezhaev, F I, Lonskaya, N I

“…Forty-three school children from 8 to 11 years old were vaccinated intranasally with two doses of a paediatric attenuated influenza vaccine developed by…”
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Interfering activity of epidemic, attenuated and recombinant strains of influenza A virus by Romanova YuR, Polezhaev, F I, Shneider, M A, Aleksandrova, G I

“…Interfering activity (IA) of the epidemic and attenuated influenza virus strains of different ts-phenotype was studied. IA was assessed by inhibition of…”
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Location of ts defects in the genome of cold-adapted recombinant influenza A virus vaccine strains by Medvedeva, T E, Lisovskaya, K V, Polezhaev, F I, Garmashova, L M, Alexandrova, G I, Ghendon, Y Z

“…The ts phenotype and location of ts mutations were studied in the genome of parent viruses and those obtained by recombination of cold-adapted strains…”
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Peculiarities of obtaining and characterization of a cold-adapted A/PR/8/34 influenza virus variant by Egorov AYu, Medvedeva, T E, Polezhaev, F I, Alexandrova, G I, Ghendon YuZ

“…The dynamics of alterations in biological properties of A/PR/8/34 virus strain was studied in the process of prolonged adaptation to the growth in chick…”
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Attenuated ts-recombinants of influenza A/USSR/77 (H1N1) virus obtained by crossing with the cold-adapted donor A/Leningrad/134/57 (H2N2) virus by Polezhaev, F I, Garmashova, L M, Koval, T A, Taranova, G P, Topuriya, N V, Aleksandrova, G I

“…Conditions of obtaining attenuated influenza virus recombinants by crossing of a cold-adapted donor with A (H1N1) influenza virus that reappeared in 1977 were…”
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Conditions for production of thermosensitive attenuated influenza virus recombinants by Polezhaev, F I, Garmashova, L M, Polyakov, Y M, Golubev, D B, Aleksandrova, G I

“…Recombination and cross-reactivation between virulent influenza viruses and a cold-adapted thermosensitive vaccine strain regularly produced genetically stable…”
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Peculiarities of obtaining attenuated thermosensitive recombinants of influenza A virus at the end of the H3N2 epidemic cycle by Polezhaev, F I, Garmashova, L M, Rumovsky, V I, Aleksandrova, G I, Smorodintsev, A A

“…The conditions of obtaining thermosensitive recombinants of the virulent A/Leningrad/82/76 (H3N2) virus with two donors of attenuation, A/Leningrad/134/17/57…”
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Study of live recombinant cold-adapted influenza bivalent vaccine of type A for use in children: an epidemiological control trial by Alexandrova, G I, Budilovsky, G N, Koval, T A, Polezhaev, F I, Garmashova, L M, Ghendon YuZ, Romanova, Y R, Smorodintsev, A A

“…Live cold-adapted recombinant bivalent vaccine of influenza type A was studied in a controlled field trial in 1982-1983 among nearly 30,000 children 3-15 years…”
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Temperature-sensitive recombinants of influenzavirus B by Polezhaev, F I, Aleksandrova, G I

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Isolation of temperature-sensitive strains of the influenza virus in the epidemic caused by the A/Victoria virus in 1975-1976 by Polezhaev, F I, Aleksandrova, G I

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Cold-adapted strain of A/Leningrad/134/47/57 (H2N2)--a special attenuation donor of live influenza vaccine for children and the isolation of its recombinants by Garmashova, L M, Polezhaev, F I, Aleksandrova, G I

“…A cold-adapted A/Leningrad/134/47/57 (H2N2) strain, a special donor of attenuation for generation of recombinant vaccine strains safe for children, has been…”
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Safety and high immunogenicity for children 3 to 15 of a mono- and a divaccine from recombinant influenza A/Brazil /11/78 (H1N1) and A/Bangkok/1/79 (H3N2) viruses obtained from a special donor attenuation base--the cold-adapted virus A/Leningrad/134/47/57 (H2N2) by Polezhaev, F I, Budilovskiĭ, G N, Garmashova, L M, Romeĭko-Gurko, Iu R, Egorov, A Iu

“…The data on complete safety and high immunogenic potency of intranasal live influenza vaccine from the recombinant A/Brazil/11/78 (H1N1) and A/Bangkok/1/79…”
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Role of temperature-sensitive mutants in the natural evolution of the influenza virus by Polezhaev, F I, Smorodintsev, A A

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Reactogenicity, genetic stability and effectiveness of a live recombinant influenza vaccine for children designed on the base of a cold-adapted attenuation donor A/Leningrad/134/47/57 by Aleksandrova, G I, Medvedeva, T E, Polezhaev, F I, Garmashova, L M, Budilovskiĭ, G N

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The possibility of the circulation of vaccinal influenza A viral strains in the biosphere by Petrov, N A, Kiselev, O I, Grinbaum, E B, Luzianina, T Ia, Polezhaev, F I, Vasilenko, S K

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Analysis of the polypeptides of epidemic strains and heat-sensitive variants of the influenza virus by Kramskaia, T A, Chetverikova, L K, Polezhaev, F I, Romeĭko-Gurko, Iu R, Poliak, R Ia

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