Search Results - "Polevaya, L"

Conformation and bioactivity. Design and discovery of novel antihypertensive drugs by Mavromoustakos, T, Zervou, M, Zoumpoulakis, P, Kyrikou, I, Benetis, N P, Polevaya, L, Roumelioti, P, Giatas, N, Zoga, A, Minakakis, P Moutevelis, Kolocouris, A, Vlahakos, D, Grdadolnik, S Golic, Matsoukas, J

“…Peptidomimitism is applied to the medicinal chemistry in order to synthesize drugs that devoid of the disadvantages of peptides. AT1 antagonists constitute a…”
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Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi--pi interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT(1) non-peptide antagonists by Polevaya, L, Mavromoustakos, T, Zoumboulakis, P, Golic Grdadolnik, S, Roumelioti, P, Giatas, N, Mutule, I, Keivish, T, Vlahakos, D V, Iliodromitis, E K, Kremastinos, D T, Matsoukas, J

“…The novel amide linked Angiotensin II (ANG II) cyclic analogue cyclo(3, 5) -[Sar(1)-Lys(3)-Glu(5)-Ile(8)] ANG II (18) has been designed, synthesized and…”
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Design, synthesis and biological evaluation of cyclic angiotensin II analogues with 3,5 side-Chain bridges: Role of C-Terminal aromatic residue and ring cluster for activity and implications in the drug design of AT1 non-peptide antagonists by Roumelioti, Panagiota, Polevaya, Ludmila, Zoumpoulakis, Panagiotis, Giatas, Nektarios, Mutule, Ilze, Keivish, Tatjana, Zoga, Anastasia, Vlahakos, Demetrios, Iliodromitis, E., Kremastinos, Demetrios, Grdadolnik, Simona Golic, Mavromoustakos, Thomas, Matsoukas, John

“…The novel amide linked Angiotensin II (ANG II) cyclic analogues: γ,ε-cyclo(3, 5)-[Sar 1-Glu 3-Lys 5-Ile 8] ANG II (I) and γ, ε-cyclo(3, 5)-[Sar 1-Glu 3-Lys…”
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The design and synthesis of a potent Angiotensin II cyclic analogue confirms the ring cluster receptor conformation of the hormone Angiotensin II by MATSOUKAS, J. M, POLEVAYA, L, ANCANS, J, MAVROMOUSTAKOS, T, KOLOCOURIS, A, ROUMELIOTI, P, VLAHAKOS, D. V, YAMDAGNI, R, QIAO WU, MOORE, G. J

“…The novel amide linked Angiotensin II potent cyclic analogue, c-[Sar1,Lys3,Glu5] ANG II 19 has been designed and synthesized in an attempt to test the aromatic…”
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Salt bridges in model peptides by SEKACIS, I, SHENDEROVICH, M, NIKIFOROVICH, G, LIEPINS, E, POLEVAYA, L, CHIPENS, G

“…A group of synthetic peptides including Boc-Lys-Phe-X-Y, X = Ala ( I, III ) or Thr ( II ), Y = Pro ( I, II ) or Ala ( III ) was studied by means of 1 H NMR…”
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Synthesis of some derivatives of the C-terminal tetrapeptide of the hormone gastrin by Smirnov, O. V., Polevaya, L. K., Chipens, G. I.

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