Search Results - "Polejaeva, I."

Cloned pigs produced by nuclear transfer from adult somatic cells by Polejaeva, Irina A, Chen, Shu-Hung, Vaught, Todd D, Page, Raymond L, Mullins, June, Ball, Suyapa, Dai, Yifan, Boone, Jeremy, Walker, Shawn, Ayares, David L, Colman, Alan, Campbell, Keith H. S

“…Since the first report of live mammals produced by nuclear transfer from a cultured differentiated cell population in 1995 (ref. 1), successful development has…”
Get full text

Risk of equine infectious anemia virus disease transmission through in vitro embryo production using somatic cell nuclear transfer by Gregg, K., Polejaeva, I.

“…Prevention and regulation of equine infectious anemia virus (EIAV) disease transmission solely depend on identification, isolation, and elimination of infected…”
Get full text

Generation of antibody- and B cell-deficient pigs by targeted disruption of the J-region gene segment of the heavy chain locus by Mendicino, M, Ramsoondar, J, Phelps, C, Vaught, T, Ball, S, LeRoith, T, Monahan, J, Chen, S, Dandro, A, Boone, J, Jobst, P, Vance, A, Wertz, N, Bergman, Z, Sun, X-Z, Polejaeva, I, Butler, J, Dai, Y, Ayares, D, Wells, K

“…A poly(A)-trap gene targeting strategy was used to disrupt the single functional heavy chain (HC) joining region (JH) of swine in primary fibroblasts…”
Get full text

Production of a Cloned Offspring and CRISPR/Cas9 Genome Editing of Embryonic Fibroblasts in Cattle by Singina, G. N., Sergiev, P. V., Lopukhov, A. V., Rubtsova, M. P., Taradajnic, N. P., Ravin, N. V., Shedova, E. N., Taradajnic, T. E., Polejaeva, I. A., Dozev, A. V., Brem, G., Dontsova, O. A., Zinovieva, N. A.

“…Somatic Cell Nuclear Transfer (SCNT) technique was used to produce the first viable cloned cattle offspring in Russia. Whole-genome SNP genotyping confirmed…”
Get full text

Targeted disruption of the porcine immunoglobulin kappa light chain locus by Ramsoondar, J, Mendicino, M, Phelps, C, Vaught, T, Ball, S, Monahan, J, Chen, S, Dandro, A, Boone, J, Jobst, P, Vance, A, Wertz, N, Polejaeva, I, Butler, J, Dai, Y, Ayares, D, Wells, K

“…Inactivation of the endogenous pig immunoglobulin (Ig) loci, and replacement with their human counterparts, would produce animals that could alleviate both the…”
Get full text

Experimental risk assessment of bovine viral diarrhea virus transmission via in vitro embryo production using somatic cell nucleus transfer by Gregg, K., Chen, S.H., Sadeghieh, S., Guerra, T., Xiang, T., Meredith, J., Polejaeva, I.

“…The objective of this study was to perform a comprehensive risk assessment on infectious disease transmission in the system of in vitro embryo production via…”
Get full text

Large scale in vivo risk assessment of bovine viral diarrhea virus (BVDV) transmission through transfer of bovine embryos produced via somatic cell nuclear transfer (SCNT) by Gregg, K., Gosch, G., Guerra, T., Chen, S.H., Xiang, T., Broek, D., Bruner, B., Polejaeva, I.

“…The objective was to use the bovine viral diarrhea virus (BVDV) as a model to assess the risk of infectious disease transmission in the system of in vitro…”
Get full text

Risk and prevention of bovine viral diarrhea virus (BVDV) transmission through embryo production via somatic cell nuclear transfer (SCNT) using oocytes from persistently infected donors by Gregg, K., Riddell, K.P., Chen, S.H., Galik, P.K., Xiang, T., Guerra, T., Marley, M.S., Polejaeva, I., Givens, M.D.

“…The objective was to assess the risk of transmission of bovine viral diarrhea virus (BVDV) through embryo production via somatic cell nuclear transfer (SCNT),…”
Get full text

Risk assessment of porcine reproductive and respiratory syndrome virus (PRRSV) transmission via somatic cell nuclear transfer (SCNT) embryo production using oocytes from commercial abattoirs by Gregg, K., Xiang, T., Arenivas, S.S., Hwang, E., Arenivas, F., Chen, S.-H., Walker, S., Picou, A., Polejaeva, I.

“…Somatic cell nuclear transfer (SCNT) technology has become a powerful tool for reproductive biology to preserve and propagate valuable genetics for livestock…”
Get full text

A sensitive and efficient detection method for bovine viral diarrhea virus (BVDV) in single preimplantation bovine embryos by Gregg, K., Chen, S.H., Guerra, T., Sadeghieh, S., Xiang, T., Meredith, J., Polejaeva, I.

“…The objective was to develop a method to accurately and efficiently detect minute amounts of bovine viral diarrhea virus (BVDV) associated with a single…”
Get full text

New advances in somatic cell nuclear transfer: application in transgenesis by Polejaeva, I.A., Campbell, K.H.S.

“…The ability to produce live offspring by nuclear transfer from cultured somatic cells provides a route for the precise genetic manipulation of large animal…”
Get full text

Comparison of meat composition from offspring of cloned and conventionally produced boars by Walker, S.C., Christenson, R.K., Ruiz, R.P., Reeves, D.E., Pratt, S.L., Arenivas, F., Williams, N.E., Bruner, B.L., Polejaeva, I.A.

“…This study compares the meat composition of the offspring from boars produced by somatic cell nuclear transfer ( n = 4) to that of the offspring from…”
Get full text

Prolactin-induced termination of obligate diapause of mink (Mustela vison) blastocysts in vitro and subsequent establishment of embryonic stem-like cells by Polejaeva, I A, Reed, W A, Bunch, T D, Ellis, L C, White, K L

“…The mink reproductive cycle includes an obligatory period of embryonic diapause and delayed implantation, which continues in vitro and reduces the efficiency…”
Get full text

670: F508del and G542X sheep models exhibit a severe cystic fibrosis phenotype, and their tracheal epithelial cells respond to human therapeutics in vitro by Perisse, I. Viotti, Fan, Z., Liu, Y., Leir, S., Wettere, A. Van, Harris, A., White, K., Polejaeva, I.

Get full text

Cloning pigs: advances and applications by Polejaeva, I A

“…Although mouse embryonic stem cells have been used widely for over a decade as an important tool for introducing precise genetic modification into the genome,…”
Get more information

A comparison of reproductive characteristics of boars generated by somatic cell nuclear transfer to highly related conventionally produced boars by Williams, N E, Walker, S C, Reeves, D E, Sherrer, E, Galvin, J M, Polejaeva, I, Rampacek, G, Benyshek, L, Christenson, R K, Graves, W M, Pratt, S L

“…This study compares the reproductive performance of boars produced by somatic cell nuclear transfer versus conventional breeding. Two different genotypes were…”
Get more information

Production of alpha 1,3-galactosyltransferase-deficient pigs by Phelps, Carol J, Koike, Chihiro, Vaught, Todd D, Boone, Jeremy, Wells, Kevin D, Chen, Shu-Hung, Ball, Suyapa, Specht, Susan M, Polejaeva, Irina A, Monahan, Jeff A, Jobst, Pete M, Sharma, Sugandha B, Lamborn, Ashley E, Garst, Amy S, Moore, Marilyn, Demetris, Anthony J, Rudert, William A, Bottino, Rita, Bertera, Suzanne, Trucco, Massimo, Starzl, Thomas E, Dai, Yifan, Ayares, David L

“…The enzyme alpha1,3-galactosyltransferase (alpha1,3GT or GGTA1) synthesizes alpha1,3-galactose (alpha1,3Gal) epitopes (Galalpha1,3Galbeta1,4GlcNAc-R), which…”
Get full text

Targeted disruption of the alpha 1, 3-galactosyltransferase gene in cloned pigs by Dai, Yifan, Vaught, T D, Boone, J, Chen, Shu-Hung, Phelps, C J, Ball, S, Monahan, JA, Jobst, P M, McCreath, K J, Lamborn, A E, Cowell-Lucero, J L, Wells, K D, Colman, A, Polejaeva, IA, Ayares, D L

“…Galactose- alpha 1, 3-galactose ( alpha 1,3Gal) is the major xenoantigen causing hyperacute rejection in pig-to-human xenotransplantation. Disruption of the…”
Get full text

Efficient generation of chimaeric mice using embryonic stem cells after long-term culture in the presence of ciliary neurotrophic factor by WOLF, E, KRAMER, R, POLEJAEVA, I, THOENEN, H, BREM, G

“…The aim of our study was to evaluate whether ciliary neurotrophic factor (CNTF) can substitute for leukaemia inhibitory factor (LIF) in maintaining…”
Get full text

Transcript levels of several epigenome regulatory genes in bovine somatic donor cells are not correlated with their cloning efficiency by Zhou, Wenli, Sadeghieh, Sanaz, Abruzzese, Ronald, Uppada, Subhadra, Meredith, Justin, Ohlrichs, Charletta, Broek, Diane, Polejaeva, Irina

“…Among many factors that potentially affect somatic cell nuclear transfer (SCNT) embryo development is the donor cell itself. Cloning potentials of somatic…”
Get more information