Search Results - "Polanovsky, O. L."

Antibody Engineering: From the Idea to Its Implementation by Polanovsky, O. L.

“…The late 1970s brought opportunities to create proteins with new properties and, in particular, various derivatives of mouse monoclonal antibodies (mAbs) owing…”
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Expression of the chimeric IgE gene in cell culture and in various mouse tissues by Rodin, D.V., Rad’ko, B.V., Kolesnikov, V.A., Polanovsky, O.L., Deyev, S.M.

“…Transient expression of recombinant gene constructs is now more widely used in gene therapy as well as in DNA vaccination. In this study, the ability of one…”
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Tissue-specific isoforms of the ubiquitous transcription factor Oct-1 by Pankratova, E V, Deyev, I E, Zhenilo, S V, Polanovsky, O L

“…The ubiquitously expressed transcription factor Oct-1 is a member of the POU protein family. It is involved in the activation of snRNA promoters and some mRNA…”
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The oct Genes and Oct Proteins by Deyev, I E, Polanovsky, O L

“…The review considers the functions and properties of Oct proteins, which belong to the POU family of transcription factors, and the roles of the POU and other…”
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Spliced oct-1 mRNA Isoforms with Untranslated Exons and a Partly Deleted Region Coding for the POU-Specific Domain by Deyev, I E, Zhenilo, S V, Polanovsky, O L

“…Transcription factor Oct-1 is involved in expression regulation of housekeeping genes, in lymphocyte differentiation, and in the immune response…”
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The Tissue-Specific Splicing of 5"-Terminal Exons of the Oct-1 Gene by Pankratova, E V, Deev, I E, Polanovsky, O L

“…It has been shown that the pre-mRNA of transcription factor Oct-1 undergoes tissue-specific splicing. The Oct-1R isoform is synthesized in mouse lymphoid…”
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Isoforms of Transcription Factor Oct-1 Synthesized in Lymphocytes by Pankratova, E V, Deyev, I E, Zhenilo, S V, Anfalova, T V, Polanovsky, O L

“…Transcription factor Oct-1 is ubiquitous, participating in expression of the cell housekeeping genes as well as in differentiation of lymphocytes and…”
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Expression of anti-tumor recombinant IgG- and IgE-like genes in eukaryotic cells by Polanovsky, O. L., Lukash, S. V., Stremovskiy, O. A., Karpenko, D. V., Deyev, S. M.

“…The tandem of humanized variable VL and VH genes (ScFv fragment 4D5) possessing a high affinity to the HER-2/neu oncogene (the epidermal growth factor receptor…”
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Allelic variants of rearranged immunoglobulin heavy and light chain genes in hybridoma PTF-02 and parent myeloma by DEYEV, S. M, URAKOV, D. N, STEPCHENKO, A. G, POLANOVSKY, O. L

“…The hybridoma PTF-02 secretes an antibody against pig transferrin. Rearranged genes for heavy and light immunoglobulin chains have been studied in the genomes…”
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Alternative Promoters and Tissue-Specific Regulation of Mouse oct-1 Gene Transcription by Pankratova, E V, Sytina, E V, Stepchenko, A G, Manuylova, E A, Polanovsky, O L

“…The gene encoding mouse transcription factor Oct-1 contains two exons, 1U and 1L, at the 5' end. Oct-1 mRNA from all tissues contains exon 1U, whereas exon 1L…”
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Expression of chimeric immunoglobulin genes in mammalian cells by Deyev, S M, Polanovsky, O L

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Expression of immunoglobulin genes tandem in eukaryotic cells under the control of T7 bacteriophage RNA polymerase by Deyev, S M, Lieber, A, Radko, B V, Polanovsky, O L

“…A tandem of recombinant mouse/human immunoglobulin (Ig) genes was constructed and inserted into the plasmid pGEM1 under the control of T7 phage RNA polymerase…”
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Oct-1 promoter region contains octamer sites and TAAT motifs recognized by Oct proteins by Pankratova, E.V, Polanovasky, O.L

“…The 5′-upstream region (1.3 kb) of the gene encoding the POU domain transcription factor Oct-1 was cloned and sequenced. CAT reporter gene analysis of this…”
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Conservative Val super(47) residue of POU homeodomain: Role in DNA recognition by Stepchenko, A G, Luchina, N N, Polanovsky, O L

“…Conservative Val super(47) residue, located in the third recognition helix of the Oct-2 POU domain, was alternately substituted with other 19 amino acids…”
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The Tissue-Specific Splicing of 5QUOTATION_MARK-Terminal Exons of the Oct-1 Gene by Pankratova, E V, Deev, I E, Polanovsky, O L

“…It has been shown that the pre-mRNA of transcription factor Oct-1 undergoes tissue-specific splicing. The Oct-1R isoform is synthesized in mouse lymphoid…”
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Conservative Val47 residue of POU homeodomain: role in DNA recognition by Stepchenko, Alexander G, Luchina, Nadezda N, Polanovsky, Oleg L

“…Conservative Val47 residue, located in the third recognition helix of the Oct‐2 POU domain, was alternately substituted with other 19 amino acids. Affinity and…”
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Production of recombinant antibodies in lymphoid and non-lymphoid cells by Deyev, Sergey M., Lieber, Andre, Radko, Boris V., Polanovsky, Oleg L.

“…A recombinant tandem of ‘chimeric’ mouse/human immunoglobulin (Ig) genes was constructed and inserted into plasmid pGEM 1 under the control of the T7…”
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Oct-1 promoter region contains octamer sites and TAAT motifs recognized by Oct proteins

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Alternative promoters and oct-1 gene tissue-specific regulation

“…Murine oct-1 gene contains exons IU and 1L at 5'-end, which are alternatively presented in oct-1 mRNA. 1U exon is presented in oct-1 mRNA expressed in all…”
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Expression of immunoglobulin genes tandem in eukaryotic cells under the control of T7 bacteriophage RNA polymerase. Discussion by DEYEV, S. M, LIEBER, A, RADKO, B. V, POLANOVSKY, O. L, DEYEV, S

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