Search Results - "Polakova, K"
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Laboratory recommendations for scoring deep molecular responses following treatment for chronic myeloid leukemia
Published in Leukemia (01-05-2015)“…Treatment of chronic myeloid leukemia (CML) with tyrosine kinase inhibitors has advanced to a stage where many patients achieve very low or undetectable levels…”
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Unraveling the complexity of tyrosine kinase inhibitor–resistant populations by ultra-deep sequencing of the BCR-ABL kinase domain
Published in Blood (29-08-2013)“…In chronic myeloid leukemia and Philadelphia chromosome–positive acute lymphoblastic leukemia, tyrosine kinase inhibitor (TKI) therapy may select for…”
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Clinical impact of low-burden BCR-ABL1 mutations detectable by amplicon deep sequencing in Philadelphia-positive acute lymphoblastic leukemia patients
Published in Leukemia (01-07-2016)Get full text
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A certified plasmid reference material for the standardisation of BCR–ABL1 mRNA quantification by real-time quantitative PCR
Published in Leukemia (01-02-2015)“…Serial quantification of BCR–ABL1 mRNA is an important therapeutic indicator in chronic myeloid leukaemia, but there is a substantial variation in results…”
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Comparison of HLA-G and MMP transcription in human tumor cell lines
Published in Neoplasma (01-01-2018)“…HLA-G antigens and matrix metalloproteinases (MMPs) expressed in various tumors are involved in tumor growth and metastasis. In this study, we investigated if…”
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Thermostable trypsin conjugates immobilized to biogenic magnetite show a high operational stability and remarkable reusability for protein digestion
Published in Nanotechnology (29-03-2013)“…In this work, magnetosomes produced by microorganisms were chosen as a suitable magnetic carrier for covalent immobilization of thermostable trypsin conjugates…”
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Field emission scanning electron microscopy (FE-SEM) as an approach for nanoparticle detection inside cells
Published in Micron (Oxford, England : 1993) (01-12-2014)“…•Stem cells labeled by SPIO NPs help in diagnostics and regenerative medicine.•FE-SEM enables to image NPs uptake and distribution within stem cells.•FE-SEM…”
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Proteomic analysis of imatinib-resistant CML-T1 cells reveals calcium homeostasis as a potential therapeutic target
Published in Oncology reports (01-09-2016)“…Chronic myeloid leukemia (CML) therapy has markedly improved patient prognosis after introduction of imatinib mesylate for clinical use. However, a subset of…”
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Demethylating agent 5-aza-2′-deoxycytidine activates HLA-G expression in human leukemia cell lines
Published in Leukemia research (01-04-2009)“…Abstract HLA-G is a non-classical HLA class I antigen primarily expressed in the extravillous cytotrophoblast. HLA-G can also be expressed at some pathological…”
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Real-time PCR quantification of major Wilms’ tumor gene 1 (WT1) isoforms in acute myeloid leukemia, their characteristic expression patterns and possible functional consequences
Published in Leukemia (01-09-2012)“…Wilms’ tumor gene 1 ( WT1 ) functions including some contradictory effects may be explained by the presence and interactions of its isoforms, however, their…”
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Impact of blood processing on estimation of soluble HLA-G
Published in Neoplasma (01-01-2011)“…HLA-G is a non-classical MHC class I antigen that functions as an immunomodulatory molecule. There are two forms of HLA-G antigens, soluble and membrane bound…”
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N-terminal region of the PB1-F2 protein is responsible for increased expression of influenza A viral protein PB1
Published in Acta virologica (Anglickâa verze) (2011)“…Influenza A virus (IAV) PB1-F2 protein is encoded by an alternative reading frame (+1) within the PB1 gene. PB1-F2 has been shown to contribute to the…”
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Recent patterns in cutaneous melanoma descriptive epidemiology in the Slovak Republic
Published in Neoplasma (01-01-2013)“…An increase in melanoma incidence in the Slovak Republic (SR) is evident during approximately the same time and maybe caused by changes in socio-economic…”
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Non-structural carbohydrates in the nutrition of high-yielding dairy cows during a transition period
Published in Czech Journal of Animal Science (01-01-2010)“…The main aim of this study was to investigate experimentally the effect of different composition of non-structural carbohydrates (NFC) in prepartum feed…”
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Activation of HLA-G expression by 5-aza-2 - deoxycytidine in malignant hematopoetic cells isolated from leukemia patients
Published in Neoplasma (2009)“…Human leukocyte antigen - G (HLA-G) is a non-classical HLA class I antigen with restricted distribution in normal tissues. Ectopic HLA-G expression observed at…”
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Modulation of HLA-G expression
Published in Neoplasma (2007)“…Recent studies demonstrated that HLA-G transcription is in some cells silenced by epigenetic mechanisms as DNA methylation and histone modification…”
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Expression of the non-classical HLA-G antigen in tumor cell lines is extremely restricted
Published in Neoplasma (2000)“…It has been proposed that tumor cells frequently associated with partial or total loss of HLA class Ia expression may abnormally express HLA-G class Ib…”
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Evaluation of Czech spring malting barleys with respect to the β-amylase allele incidence
Published in Plant breeding (01-06-2006)“…Strong enzymatic activities in the germinating barley grain, together with protein and starch content, are crucial for high extraction values in the resulting…”
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Coding region single nucleotide polymorphism in the barley low-pI, alpha-amylase gene Amy32b
Published in Theoretical and applied genetics (01-05-2005)“…Barley alpha-amylase variability influences the quality of barley grain in the brewing, feed and food industries. alpha-Amylase proteins are encoded by…”
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