Search Results - "Polakova, Eva"

Genetic Testing in Patients with Hypertrophic Cardiomyopathy by Bonaventura, Jiri, Polakova, Eva, Vejtasova, Veronika, Veselka, Josef

“…Hypertrophic cardiomyopathy (HCM) is a common inherited heart disease with an estimated prevalence of up to 1 in 200 individuals. In the majority of cases, HCM…”
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Prediction of Sudden Cardiac Arrest After Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: ASA-SCARRE Risk Score by Veselka, Josef, Liebregts, Max, Cooper, Robert, Faber, Lothar, Januska, Jaroslav, Kashtanov, Maksim, Tesarkova, Klara Hulikova, Hansen, Peter Riis, Seggewiss, Hubert, Shloydo, Eugene, Popov, Kirill, Hansvenclova, Eva, Polakova, Eva, ten Berg, Jurriën, Stables, Rodney Hilton, Jarkovsky, Jiri, Bonaventura, Jiri

“…This study aimed to derive a new score, the Alcohol Septal Ablation-Sudden Cardiac ARREst (ASA-SCARRE) risk score, that can be easily used to evaluate the risk…”
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Relationship Between Genotype Status and Clinical Outcome in Hypertrophic Cardiomyopathy by Bonaventura, Jiri, Rowin, Ethan J, Chan, Raymond H, Chin, Michael T, Puchnerova, Veronika, Polakova, Eva, Macek, Jr, Milan, Votypka, Pavel, Batorsky, Rebecca, Perera, Gayani, Koethe, Benjamin, Veselka, Josef, Maron, Barry J, Maron, Martin S

“…The genetic basis of hypertrophic cardiomyopathy (HCM) is complex, and the relationship between genotype status and clinical outcome is incompletely resolved…”
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Vincristine-Induced Overexpression of P-Glycoprotein in L1210 Cells Is Associated with Remodeling of Cell Surface Saccharides by Sulová, Zdenka, Mislovičová, Danica, Gibalová, Lenka, Vajčnerová, Zuzana, Poláková, Eva, Uhrík, Branislav, Tylková, Lucia, Kovárová, Annamária, Sedlák, Ján, Breier, Albert

“…Multidrug resistance of murine leukemic cell line L1210/VCR (R), obtained by adaptation of parental L1210 cells (S) on vincristine, is associated with…”
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Management of Massive Pulmonary Embolism by Polaková, Eva, Veselka, Josef

“…Abstract Pulmonary embolism is a potentially lethal manifestation of venous thromboembolic disease. It is one of the three main causes of cardiovascular…”
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Mitochondrial dysfunctions during progression of dystrophic cardiomyopathy by Kyrychenko, Victoria, Poláková, Eva, Janíček, Radoslav, Shirokova, Natalia

“…Graphical abstract…”
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Type 1 and 2 IP3 Receptors Respond Differently to Catecholamines and Stress by Krizanova, Olga, Holotnakova, Tereza, Jurkovicova, Dana, Polakova, Eva, Zahradnikova, Alexandra, Lacinova, Lubica, Kvetňanský, Richard, Myslivecek, Jaromir, Pastorekova, Silvia

“…Type 1 and 2 inositol 1,4,5‐trisphosphate (IP3) receptors have been found in cardiac tissue, although they are localized in different types of cells. While the…”
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Maximal acceleration of Ca2+ release refractoriness by β‐adrenergic stimulation requires dual activation of kinases PKA and CaMKII in mouse ventricular myocytes by Poláková, Eva, Illaste, Ardo, Niggli, Ernst, Sobie, Eric A.

“…Key points Refractoriness of calcium release in heart cells is altered in several disease states, but the physiological mechanisms that regulate this process…”
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Posttranslational modifications of cardiac ryanodine receptors: Ca2+ signaling and EC-coupling by Niggli, Ernst, Ullrich, Nina D., Gutierrez, Daniel, Kyrychenko, Sergii, Poláková, Eva, Shirokova, Natalia

“…In cardiac muscle, a number of posttranslational protein modifications can alter the function of the Ca2+ release channel of the sarcoplasmic reticulum (SR),…”
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L1210 cells cultivated under the selection pressure of doxorubicin or vincristine express common mechanisms of multidrug resistance based on the overexpression of P-glycoprotein by Boháčová, Viera, Sulová, Zdena, Dovinová, Ima, Poláková, Eva, Barančík, Miroslav, Uhrík, Branislav, Orlický, Jozef, Breier, Albert

“…Multidrug resistance of neoplastic tissue is often associated with the overexpression and increased drug transport activity of plasma membrane transporters…”
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Alterations in T-tubule and dyad structure in heart disease: challenges and opportunities for computational analyses by Poláková, Eva, Sobie, Eric A

“…Compelling recent experimental results make clear that sub-cellular structures are altered in ventricular myocytes during the development of heart failure, in…”
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Hierarchical accumulation of RyR post-translational modifications drives disease progression in dystrophic cardiomyopathy by Kyrychenko, Sergii, Poláková, Eva, Kang, Chifei, Pocsai, Krisztina, Ullrich, Nina D, Niggli, Ernst, Shirokova, Natalia

“…Duchenne muscular dystrophy (DMD) is a muscle disease with serious cardiac complications. Changes in Ca(2+) homeostasis and oxidative stress were recently…”
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Effectiveness of alcohol septal ablation for hypertrophic obstructive cardiomyopathy in patients with late gadolinium enhancement on cardiac magnetic resonance by Polaková, Eva, Liebregts, Max, Marková, Natália, Adla, Theodor, Kara, Basak, ten Berg, Jurriën, Bonaventura, Jiří, Veselka, Josef

“…According to European guidelines, alcohol septal ablation (ASA) for hypertrophic obstructive cardiomyopathy (HOCM) may be less effective in patients with…”
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Update on alcohol septal ablation for hypertrophic obstructive cardiomyopathy by Veselka, Josef, Polaková, Eva, Bonaventura, Jiří

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TAVI-in-TAVI in a patient after alcohol septal ablation by Polaková, Eva, Adlová, Radka, Hájek, Petr, Veselka, Josef

“…Cardiovascular medicine at its beginning was dominated by surgical treatment options. The trend of the last decades is heading towards catheterization…”
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Mid-term outcomes of patients with Lotus and Evolut transcatheter valves by Hájek, Petr, Polaková, Eva, Adlová, Radka, Horváth, Martin, Hansvenclová, Eva, Pecková, Monika, Veselka, Josef

“…Introduction: Long-term data on the Lotus® (Boston Scientific, USA) valve are lacking. Aim: To evaluate mid-term outcomes of aortic stenosis patients treated…”
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Outcomes of Patients With Hypertrophic Obstructive Cardiomyopathy and Pacemaker Implanted After Alcohol Septal Ablation by Veselka, Josef, Liebregts, Max, Cooper, Robert, Faber, Lothar, Januska, Jaroslav, Kashtanov, Maksim, Tesarkova, Klara Hulikova, Hansen, Peter Riis, Seggewiss, Hubert, Shloydo, Eugene, Popov, Kirill, Hansvenclova, Eva, Bonaventura, Jiri, Berg, Jurriën ten, Stables, Rodney Hilton, Polakova, Eva

“…BACKGROUNDAtrioventricular block is a frequent major complication after alcohol septal ablation (ASA). OBJECTIVESThe aim of this study was to evaluate the…”
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Calcium spike variability in cardiac myocytes results from activation of small cohorts of ryanodine receptor 2 channels by Janicek, Radoslav, Zahradnikova Jr, Alexandra, Polakova, Eva, Pavelkova, Jana, Zahradnik, Ivan, Zahradnikova, Alexandra

“…Key points •  Cardiac myocytes contract due to the upsurge in intracellular calcium concentration resulting from the activation of ryanodine receptor (RyR)…”
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Simulations of Subcellular Heterogeneity in Calcium Blink Kinetics by Nunez Acosta, Elisa, Polakova, Eva, Sobie, Eric A.

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Local calcium release activation by DHPR calcium channel openings in rat cardiac myocytes by Polakova, Eva, Zahradnikova Jr, Alexandra, Pavelkova, Jana, Zahradnik, Ivan, Zahradnikova, Alexandra

“…The principal role of calcium current in the triggering of calcium release in cardiac myocytes is well recognized. The mechanism of how calcium current ( I Ca…”
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