Search Results - "Polach, K. J."

Mechanism of Protein Access to Specific DNA Sequences in Chromatin: A Dynamic Equilibrium Model for Gene Regulation by Polach, K.J., Widom, J.

“…We present evidence for a mechanism by which regulatory proteins may gain access to their target DNA sequences in chromatin. In this model, nucleosomes are…”
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A Model for the Cooperative Binding of Eukaryotic Regulatory Proteins to Nucleosomal Target Sites by Polach, K.J., Widom, J.

“…The mechanism by which gene regulatory proteins gain access to their DNA target sequences in chromatin is not known. We recently showed that nucleosomes are…”
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Effects of core histone tail domains on the equilibrium constants for dynamic dna site accessibility in nucleosomes by Polach, K.J., Lowary, P.T., Widom, J.

“…The N and C-terminal tail domains of the core histones play important roles in gene regulation, but the mechanisms through which they act are not known. These…”
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Restriction enzymes as probes of nucleosome stability and dynamics by Polach, K J, Widom, J

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Coupled-enzymatic assays for the rate and mechanism of DNA site exposure in a nucleosome by Protacio, R.U, Polach, K.J, Widom, J

“…The packaging of DNA in nucleosomes presents obstacles to the action of gene regulatory proteins and polymerases on their natural chromatin substrates. We…”
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Cooperative Binding of ATP and RNA Substrates to the DEAD/H Protein DbpA by Polach, Kevin J, Uhlenbeck, Olke C

“…Unlike most DEAD/H proteins, the purified Escherichia coli protein DbpA demonstrates high specificity for its 23S rRNA substrate in vitro. Here we describe…”
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Organic analyses of an actual and simulated mixed waste: Hanford's organic complexant waste revisited by Toste, A. P., Osborn, B. C., Polach, K. J., Lechner-Fish, T. J.

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Fuel cycle and nuclear waste: Chemodynamics of EDTA in a simulated, mixed waste: Chemo-degradation vs. gamma-radiolysis by Toste, A. P., Polach, K. J., Ohnuki, T.

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