Search Results - "Poirier, Marc"
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Social integration and acclimation of translocated bighorn sheep (Ovis canadensis)
Published in Biological conservation (01-02-2018)“…Translocation of animals to reinforce small populations is a widespread technique in conservation biology. Recent reviews of translocation science underline…”
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Genetic decline, restoration and rescue of an isolated ungulate population
Published in Evolutionary applications (01-08-2019)“…Isolation of small populations is expected to reduce fitness through inbreeding and loss of genetic variation, impeding population growth and compromising…”
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Thermodynamic and kinetic studies of a catalytic process to convert glycerol into solketal as an oxygenated fuel additive
Published in Fuel (Guildford) (01-01-2014)“…[Display omitted] •Thermodynamics and kinetics of glycerol ketalization were studied for the first time.•External mass transfer resistance was completely…”
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A new continuous-flow process for catalytic conversion of glycerol to oxygenated fuel additive: Catalyst screening
Published in Applied energy (15-06-2014)“…[Display omitted] •A continuous-flow process for catalytic synthesis of solketal from glycerol.•Six different heterogeneous acid catalysts were studied in the…”
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Catalytic conversion of glycerol to oxygenated fuel additive in a continuous flow reactor: Process optimization
Published in Fuel (Guildford) (15-07-2014)“…[Display omitted] •A continuous flow process for synthesis of solketal from glycerol was optimized.•A maximum yield of 94±2% was obtained at optimum…”
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Texas field crickets (Gryllus texensis) use visual cues to place learn but perform poorly when intra- and extra-maze cues conflict
Published in Learning & behavior (01-09-2022)“…Central place foraging field crickets are an ideal system for studying the adaptive value of learning and memory, but more research is needed on ecologically…”
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Solution to the C 3 –Arylation of Indazoles: Development of a Scalable Method
Published in Organic letters (01-07-2016)Get full text
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How general is cognitive ability in non-human animals? A meta-analytical and multi-level reanalysis approach
Published in Proceedings of the Royal Society. B, Biological sciences (09-12-2020)“…General intelligence has been a topic of high interest for over a century. Traditionally, research on general intelligence was based on principal component…”
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Solution to the C3–Arylation of Indazoles: Development of a Scalable Method
Published in Organic letters (01-07-2016)“…3-(Hetero)arylindazoles are important motifs in several biologically active compounds. Mild and flexible palladium-mediated Negishi reaction conditions are…”
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THE NAFTA CHAPTER 11 EXPROPRIATION DEBATE THROUGH THE EYES OF A PROPERTY THEORIST
Published in Environmental law (Portland, Ore.) (22-09-2003)“…The limits set to property by other public interests present themselves as a branch of what is called the police power of the State. The boundary at which the…”
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Discovery of a 3‑(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity
Published in Journal of medicinal chemistry (13-04-2017)“…Leucine-rich repeat kinase 2 (LRRK2) is a large, multidomain protein which contains a kinase domain and GTPase domain among other regions. Individuals…”
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pH-Switchable Phase-Transfer Agents for Host Cell Protein Rejection in the Cascaded Biocatalytic Synthesis of an Active Pharmaceutical Ingredient
Published in Organic process research & development (20-01-2023)“…Given the increased reliance on multienzymatic cascades to synthesize biologically inspired small molecule drug candidates, the pharmaceutical industry…”
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Extrapolation of dynamic load behaviour on hydroelectric turbine blades with cyclostationary modelling
Published in Mechanical systems and signal processing (01-01-2017)“…In this paper, we present the application of cyclostationary modelling for the extrapolation of short stationary load strain samples measured in situ on…”
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Manufacturing Process Development for the Biaryl Ether Fragment of Nemtabrutinib (MK-1026)
Published in Organic process research & development (17-11-2023)“…MK-1026, also known as nemtabrutinib (1), has been developed as a reversible Bruton’s tyrosine kinase (BTK) inhibitor for the treatment of chronic lymphocytic…”
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Development of a Robust Manufacturing Route for Molnupiravir, an Antiviral for the Treatment of COVID-19
Published in Organic process research & development (17-12-2021)“…Herein is described the development of a large-scale manufacturing process for molnupiravir, an orally dosed antiviral that was recently demonstrated to be…”
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Development of a stereoselective and scalable process for the preparation of a methylcyclobutanol-pyridyl ether
Published in Bioorganic & medicinal chemistry (15-02-2018)“…[Display omitted] The evolution of a scalable process for the preparation of methylcyclobutanol-pyridyl ether 1 is described. Key aspects of this development…”
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Polymorphs, Particle Size, and a Pandemic: Development of a Scalable Crystallization Process for Molnupiravir, an Antiviral for the Treatment of COVID-19
Published in Organic process research & development (17-11-2023)“…Molnupiravir is a small-molecule active pharmaceutical ingredient (API) prodrug of a nucleoside analog that was demonstrated to be efficacious for the…”
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Discovery and Development of an Unusual Organocatalyst for the Conversion of Thymidine to Furanoid Glycal
Published in Organic process research & development (18-03-2022)“…Our work required a reliable efficient preparation of 2-trimethylsilyloxymethyl((2R,3S)-3-(trimethylsilyloxy)-2,3-dihydrofuran (glycal 1). The best literature…”
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Diverse Catalytic Reactions for the Stereoselective Synthesis of Cyclic Dinucleotide MK-1454
Published in Journal of the American Chemical Society (06-04-2022)“…As practitioners of organic chemistry strive to deliver efficient syntheses of the most complex natural products and drug candidates, further innovations in…”
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