Search Results - "Pohlmann, A."
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Transatlantic spread of highly pathogenic avian influenza H5N1 by wild birds from Europe to North America in 2021
Published in Scientific reports (11-07-2022)“…Highly pathogenic avian influenza (HPAI) viruses of the A/Goose/Guangdong/1/1996 lineage (GsGd), which threaten the health of poultry, wildlife and humans, are…”
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2
Somatic DNA demethylation generates tissue-specific methylation states and impacts flowering time
Published in The Plant cell (29-03-2022)“…Cytosine methylation is a reversible epigenetic modification of DNA. In plants, removal of cytosine methylation is accomplished by the four members of the…”
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A paper-based multiplexed transaminase test for low-cost, point-of-care liver function testing
Published in Science translational medicine (19-09-2012)“…In developed nations, monitoring for drug-induced liver injury through serial measurements of serum transaminases [aspartate aminotransferase (AST) and alanine…”
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4
How bold is blood oxygenation level-dependent (BOLD) magnetic resonance imaging of the kidney? Opportunities, challenges and future directions
Published in Acta Physiologica (01-01-2015)“…Renal tissue hypoperfusion and hypoxia are key elements in the pathophysiology of acute kidney injury and its progression to chronic kidney disease. Yet, in…”
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High Prevalence of Highly Variable Atypical Porcine Pestiviruses Found in Germany
Published in Transboundary and emerging diseases (01-10-2017)“…Summary Recently, a novel atypical porcine pestivirus (APPV) with significant distribution was described in the USA. Subsequent screening of the German pig…”
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Skin penetration and dermal tolerability of acrylic nanocapsules: Influence of the surface charge and a chitosan gel used as vehicle
Published in International journal of pharmaceutics (30-06-2016)“…[Display omitted] For an improved understanding of the relevant particle features for cutaneous use, we studied the effect of the surface charge of acrylic…”
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Imiquimod-loaded nanocapsules improve cytotoxicity in cervical cancer cell line
Published in European journal of pharmaceutics and biopharmaceutics (01-03-2019)“…[Display omitted] This paper proposes the development of imiquimod-loaded polymeric nanocapsules formulation for the treatment of cervical cancer. The…”
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Tretinoin-loaded nanocapsules: Preparation, physicochemical characterization, and photostability study
Published in International journal of pharmaceutics (20-03-2008)“…The aim of this study was to prepare and characterize tretinoin-loaded nanocapsules as well as to evaluate the influence of this nanoencapsulation on tretinoin…”
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New pectin-based hydrogel containing imiquimod-loaded polymeric nanocapsules for melanoma treatment
Published in Drug delivery and translational research (01-12-2020)“…We developed a pectin-based hydrogel containing nanocapsules as a new strategy for melanoma treatment. Our first objective was to evaluate the…”
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IgG functionalized polymeric nanoparticles for oral insulin administration
Published in International journal of pharmaceutics (25-06-2022)“…[Display omitted] The oral route is the best way to administer a drug; however, fitting peptide drugs in this route is a major challenge. In insulin cases,…”
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Chitosan as a coating material for nanoparticles intended for biomedical applications
Published in Reactive & functional polymers (01-02-2020)“…This review provides a comprehensive and updated overview of the state of the art related to the biomedical applications of nanoparticles coated with chitosan…”
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Nanocarriers for optimizing the balance between interfollicular permeation and follicular uptake of topically applied clobetasol to minimize adverse effects
Published in Journal of controlled release (10-02-2016)“…The treatment of various hair disorders has become a central focus of good dermatologic patient care as it affects men and women all over the world. For many…”
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13
Lipid-core nanocapsules increase the oral efficacy of quercetin in cutaneous leishmaniasis
Published in Parasitology (01-11-2017)“…New oral treatments are needed for all forms of leishmaniasis. Here, the improved oral efficacy of quercetin (Qc) and its penta-acetylated derivative (PQc) was…”
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14
Effects of indomethacin‐loaded nanocapsules in experimental models of inflammation in rats
Published in British journal of pharmacology (01-10-2009)“…Background and purpose: The effects of systemic treatment with indomethacin‐loaded nanocapsules (IndOH‐NC) were compared with those of free indomethacin…”
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15
Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion
Published in Neuro-oncology (Charlottesville, Va.) (01-11-2013)“…Glioblastomas are the most aggressive primary brain tumors in humans. Microglia/brain macrophage accumulation in and around the tumor correlates with…”
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Anti-HPV Nanoemulsified-Imiquimod: A New and Potent Formulation to Treat Cervical Cancer
Published in AAPS PharmSciTech (06-01-2020)“…Cervical cancer is associated with the human papilloma virus (HPV) and nowadays is the fourth most frequent cancer among women. One of the treatments for this…”
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Sublingual tablets containing spray-dried carvedilol-loaded nanocapsules: development of an innovative nanomedicine
Published in Pharmaceutical development and technology (20-10-2020)“…The aim of this study was to propose the use of spray-dried mucoadhesive carvedilol-loaded nanocapsules in the formulation of sublingual tablets. There is no…”
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Characterization of rheology and release profiles of olanzapine-loaded lipid-core nanocapsules in thermosensitive hydrogel
Published in Journal of nanoscience and nanotechnology (01-12-2013)“…In this study we developed a new drug delivery system for olanzanpine comprised of drug-loaded lipid-core nanocapsules incorporated in a thermosensitive…”
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Nanoencapsulation of tacrolimus in lipid-core nanocapsules showed similar immunosuppressive activity after oral and intraperitoneal administrations
Published in Journal of biomedical nanotechnology (01-08-2014)“…Tacrolimus is widely used in the prophylaxis of solid-organ transplant rejection. Several studies have reported that tacrolimus has variable and poor…”
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Early effects of an x-ray contrast medium on renal T2/T2 MRI as compared to short-term hyperoxia, hypoxia and aortic occlusion in rats
Published in Acta Physiologica (01-06-2013)“…Aim X‐ray contrast media (CM) can cause acute kidney injury (AKI). Medullary hypoxia is pivotal in CM‐induced AKI, as indicated by invasively and pin‐point…”
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