Search Results - "Pohl, Nicole M"

Enhanced Ca2+-Sensing Receptor Function in Idiopathic Pulmonary Arterial Hypertension by Yamamura, Aya, Guo, Qiang, Yamamura, Hisao, Zimnicka, Adriana M, Pohl, Nicole M, Smith, Kimberly A, Fernandez, Ruby A, Zeifman, Amy, Makino, Ayako, Dong, Hui, Yuan, Jason X.-J

“…RATIONALE:A rise in cytosolic Ca concentration ([Ca]cyt) in pulmonary arterial smooth muscle cells (PASMC) is an important stimulus for pulmonary…”
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Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension by Tang, Haiyang, Yamamura, Aya, Yamamura, Hisao, Song, Shanshan, Fraidenburg, Dustin R, Chen, Jiwang, Gu, Yali, Pohl, Nicole M, Zhou, Tong, Jiménez-Pérez, Laura, Ayon, Ramon J, Desai, Ankit A, Goltzman, David, Rischard, Franz, Khalpey, Zain, Black, Stephan M, Garcia, Joe G N, Makino, Ayako, Yuan, Jason X J

“…An increase in cytosolic free Ca(2+) concentration ([Ca(2+)]cyt) in pulmonary arterial smooth muscle cells (PASMC) is a major trigger for pulmonary…”
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MicroRNA-mediated downregulation of K + channels in pulmonary arterial hypertension by Babicheva, Aleksandra, Ayon, Ramon J, Zhao, Tengteng, Ek Vitorin, Jose F, Pohl, Nicole M, Yamamura, Aya, Yamamura, Hisao, Quinton, Brooke A, Ba, Manqing, Wu, Linda, Ravellette, Keeley S, Rahimi, Shamin, Balistrieri, Francesca, Harrington, Angela, Vanderpool, Rebecca R, Thistlethwaite, Patricia A, Makino, Ayako, Yuan, Jason X-J

“…Downregulated expression of K channels and decreased K currents in pulmonary artery smooth muscle cells (PASMC) have been implicated in the development of…”
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Transcriptional regulation and biological functions of selenium-binding protein 1 in colorectal cancer in vitro and in nude mouse xenografts by Pohl, Nicole M, Tong, Chang, Fang, Wenfeng, Bi, Xiuli, Li, Tianhong, Yang, Wancai

“…It has been shown that selenium-binding protein 1 (SBP1) is significantly downregulated in different human cancers. Its regulation and function have not yet…”
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Functional and physical interaction between the selenium-binding protein 1 (SBP1) and the glutathione peroxidase 1 selenoprotein by Fang, Wenfeng, Goldberg, Marci L., Pohl, Nicole M., Bi, Xiuli, Tong, Chang, Xiong, Bin, Koh, Timothy J., Diamond, Alan M., Yang, Wancai

“…Selenium-binding protein (SBP) 1 is present in reduced levels in several cancer types as compared with normal tissues, and lower levels are associated with…”
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Dihydropyridine Ca2+ Channel Blockers Increase Cytosolic [Ca2+] by Activating Ca2+-sensing Receptors in Pulmonary Arterial Smooth Muscle Cells by Yamamura, Aya, Yamamura, Hisao, Guo, Qiang, Zimnicka, Adriana M, Wan, Jun, Ko, Eun A, Smith, Kimberly A, Pohl, Nicole M, Song, Shanshan, Zeifman, Amy, Makino, Ayako, Yuan, Jason X.-J

“…RATIONALE:An increase in cytosolic free Ca concentration ([Ca]cyt) in pulmonary arterial smooth muscle cells (PASMC) is a major trigger for pulmonary…”
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Stress-induced c-Jun-dependent Vitamin D Receptor (VDR) Activation Dissects the Non-classical VDR Pathway from the Classical VDR Activity by Li, Qing-Ping, Qi, Xiaomei, Pramanik, Rocky, Pohl, Nicole M., Loesch, Mathew, Chen, Guan

“…Vitamin D receptor (VDR) is a ligand-dependent transcription factor that mediates vitamin D3-induced gene expression. Our previous work has established that…”
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Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension by Smith, Kimberly A, Voiriot, Guillaume, Tang, Haiyang, Fraidenburg, Dustin R, Song, Shanshan, Yamamura, Hisao, Yamamura, Aya, Guo, Qiang, Wan, Jun, Pohl, Nicole M, Tauseef, Mohammad, Bodmer, Rolf, Ocorr, Karen, Thistlethwaite, Patricia A, Haddad, Gabriel G, Powell, Frank L, Makino, Ayako, Mehta, Dolly, Yuan, Jason X-J

“…Hypoxic pulmonary vasoconstriction (HPV) is an important physiological response that optimizes the ventilation/perfusion ratio. Chronic hypoxia causes vascular…”
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Enhanced Ca(2+)-sensing receptor function in idiopathic pulmonary arterial hypertension by Yamamura, Aya, Guo, Qiang, Yamamura, Hisao, Zimnicka, Adriana M, Pohl, Nicole M, Smith, Kimberly A, Fernandez, Ruby A, Zeifman, Amy, Makino, Ayako, Dong, Hui, Yuan, Jason X-J

“…A rise in cytosolic Ca(2+) concentration ([Ca(2+)](cyt)) in pulmonary arterial smooth muscle cells (PASMC) is an important stimulus for pulmonary…”
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Notch Activation of Ca2+ Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension by Smith, Kimberly A., Voiriot, Guillaume, Tang, Haiyang, Fraidenburg, Dustin R., Song, Shanshan, Yamamura, Hisao, Yamamura, Aya, Guo, Qiang, Wan, Jun, Pohl, Nicole M., Tauseef, Mohammad, Bodmer, Rolf, Ocorr, Karen, Thistlethwaite, Patricia A., Haddad, Gabriel G., Powell, Frank L., Makino, Ayako, Mehta, Dolly, Yuan, Jason X.-J.

“…Hypoxic pulmonary vasoconstriction (HPV) is an important physiological response that optimizes the ventilation/perfusion ratio. Chronic hypoxia causes vascular…”
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Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice by Bi, Xiuli, Pohl, Nicole M., Qian, Zhibin, Yang, George R., Gou, Yuan, Guzman, Grace, Kajdacsy-Balla, Andre, Iozzo, Renato V., Yang, Wancai

“…Previous studies have shown that decorin expression is significantly reduced in colorectal cancer tissues and cancer cells, and genetic deletion of the decorin…”
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Activation of Notch signaling by short-term treatment with Jagged-1 enhances store-operated Ca(2+) entry in human pulmonary arterial smooth muscle cells by Yamamura, Hisao, Yamamura, Aya, Ko, Eun A, Pohl, Nicole M, Smith, Kimberly A, Zeifman, Amy, Powell, Frank L, Thistlethwaite, Patricia A, Yuan, Jason X-J

“…Notch signaling plays a critical role in controlling proliferation and differentiation of pulmonary arterial smooth muscle cells (PASMC). Upregulated Notch…”
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Dihydropyridine Ca(2+) channel blockers increase cytosolic [Ca(2+)] by activating Ca(2+)-sensing receptors in pulmonary arterial smooth muscle cells by Yamamura, Aya, Yamamura, Hisao, Guo, Qiang, Zimnicka, Adriana M, Wan, Jun, Ko, Eun A, Smith, Kimberly A, Pohl, Nicole M, Song, Shanshan, Zeifman, Amy, Makino, Ayako, Yuan, Jason X-J

“…An increase in cytosolic free Ca(2+) concentration ([Ca(2+)](cyt)) in pulmonary arterial smooth muscle cells (PASMC) is a major trigger for pulmonary…”
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p38α Antagonizes p38γ Activity through c-Jun-dependent Ubiquitin-proteasome Pathways in Regulating Ras Transformation and Stress Response by Qi, Xiaomei, Pohl, Nicole M., Loesch, Mathew, Hou, Songwang, Li, Rongshan, Qin, Jian-Zhong, Cuenda, Ana, Chen, Guan

“…p38 MAPK family consists of four isoform proteins (α, β, γ, and δ) that are activated by the same stimuli, but the information about how these proteins act…”
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Deacetylation of MicroRNA-124 in Fibroblasts: Role in Pulmonary Hypertension by Pohl, Nicole M, Fernandez, Ruby A, Smith, Kimberly A, Yuan, Jason X.-J

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A sequence variant in the phospholipase C epsilon C2 domain is associated with esophageal carcinoma and esophagitis by Wang, Li-Dong, Bi, Xiuli, Song, Xin, Pohl, Nicole M., Cheng, Yulan, Zhou, Yixing, Shears, Stephen, Ansong, Emmanuel, Xing, Mengtao, Wang, Shaomeng, Xu, Xiao-Chun, Huang, Peng, Xu, Liyan, Wang, Liang, Fan, Zongmin, Zhao, Xueke, Dong, Huali, Meltzer, Stephen J., Ding, Ivan, Yang, Wancai

“…A single‐nucleotide polymorphism (rs2274223: A5780G:His1927Arg) in the phospholipase C epsilon gene (PLCϵ) was recently identified as a susceptibility locus…”
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Loss of JNK2 increases intestinal tumor susceptibility in Apc1638+/― mice with dietary modulation by XIULI BI, POHL, Nicole M, ZHINAN YIN, WANCAI YANG

“…A recent study has shown that c-Jun NH2-terminal kinases (JNKs) 2 interacts with and inhibits β-catenin signaling in vitro. To determine the role of genetic…”
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Abstract 18495: Lung Inflammation Impairs Hypoxic Pulmonary Vasoconstriction Through Activation of Nuclear Factor of Activated T-Cells by Fraidenburg, Dustin R, Voiriot, Guillaume, Pohl, Nicole M, Smith, Kimberly A, Yuan, Jason X

“…Abstract only Hypoxic pulmonary vasoconstriction (HPV) is an important physiologic mechanism that directs blood flow away from poorly ventilated regions of the…”
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Selectively upregulated microRNAs in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension by Pohl, Nicole M., Makino, Ayako, Yuan, Jason X.‐J.

“…Pulmonary vascular remodeling is a major cause for the elevated pulmonary vascular resistance in patients with idiopathic pulmonary arterial hypertension…”
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Notch Activation of Ca 2+ Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension by Smith, Kimberly A., Voiriot, Guillaume, Tang, Haiyang, Fraidenburg, Dustin R., Song, Shanshan, Yamamura, Hisao, Yamamura, Aya, Guo, Qiang, Wan, Jun, Pohl, Nicole M., Tauseef, Mohammad, Bodmer, Rolf, Ocorr, Karen, Thistlethwaite, Patricia A., Haddad, Gabriel G., Powell, Frank L., Makino, Ayako, Mehta, Dolly, Yuan, Jason X.-J.

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