Search Results - "Pogliaghi, Gabriele"

Intratumoral Genetic Heterogeneity in Papillary Thyroid Cancer: Occurrence and Clinical Significance by Fugazzola, Laura, Muzza, Marina, Pogliaghi, Gabriele, Vitale, Mario

“…Intratumoral heterogeneity (ITH refers to a subclonal genetic diversity observed within a tumor. ITH is the consequence of genetic instability and accumulation…”
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FAM83B is involved in thyroid cancer cell differentiation and migration by Cirello, Valentina, Grassi, Elisa Stellaria, Pogliaghi, Gabriele, Ghiandai, Viola, Ermellino, Laura, Muzza, Marina, Gazzano, Giacomo, Persani, Luca, Colombo, Carla, Fugazzola, Laura

“…FAM83B has been recently identified as an oncogene, but its role in thyroid cancers (TC) is still unclear. We examined the expression of FAM83B and its…”
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The molecular and gene/miRNA expression profiles of radioiodine resistant papillary thyroid cancer by Colombo, Carla, Minna, Emanuela, Gargiuli, Chiara, Muzza, Marina, Dugo, Matteo, De Cecco, Loris, Pogliaghi, Gabriele, Tosi, Delfina, Bulfamante, Gaetano, Greco, Angela, Fugazzola, Laura, Borrello, Maria Grazia

“…Abstract Background Papillary thyroid cancer (PTC) is the most frequent endocrine tumor. Radioiodine (RAI) treatment is highly effective in these tumors, but…”
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Triple-A Syndrome (TAS): An In-Depth Overview on Genetic and Phenotype Heterogeneity by Pogliaghi, Gabriele, Cangiano, Biagio, Duminuco, Paolo, Vezzoli, Valeria, Bonomi, Marco

“…Triple-A Syndrome (TAS) is a rare autosomal recessive disorder characterized by three cardinal symptoms: alacrimia, achalasia and adrenal insufficiency due to…”
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Thyroid cancer harboring PTEN and TP53 mutations: A peculiar molecular and clinical case report by Colombo, Carla, Pogliaghi, Gabriele, Tosi, Delfina, Muzza, Marina, Bulfamante, Gaetano, Persani, Luca, Fugazzola, Laura, Cirello, Valentina

“…To date, the molecular mechanisms that underline aggressiveness and resistance to tyrosine kinase inhibitors in some thyroid carcinomas (TCs) are not known…”
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Clinical and Genetic Features of a Large Monocentric Series of Familial Non-Medullary Thyroid Cancers by Cirello, Valentina, Colombo, Carla, Karapanou, Olga, Pogliaghi, Gabriele, Persani, Luca, Fugazzola, Laura

“…Several low penetration susceptibility risk loci or genes have been proposed in recent years with a possible causative role for familial non-medullary thyroid…”
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Radiofrequency ablation is an effective treatment for Bethesda III thyroid nodules without genetic alterations by Fugazzola, Laura, Deandrea, Maurilio, Borgato, Stefano, Dell'Acqua, Marco, Retta, Francesca, Mormile, Alberto, Carzaniga, Chiara, Gazzano, Giacomo, Pogliaghi, Gabriele, Muzza, Marina, Persani, Luca

“…Radiofrequency ablation (RFA) is effective in the treatment of thyroid nodules, leading to a 50-90% reduction with respect to baseline. Current guidelines…”
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Liquid biopsy in thyroid cancer: from circulating biomarkers to a new prospective of tumor monitoring and therapy by Pogliaghi, Gabriele

“…Recently, liquid biopsy has attracted much interest as a tool for early cancer screening, prognosis, monitoring and response to treatment in many different…”
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The thyroid risk score (TRS) for nodules with indeterminate cytology by Colombo, Carla, Muzza, Marina, Pogliaghi, Gabriele, Palazzo, Sonia, Vannucchi, Guia, Vicentini, Leonardo, Persani, Luca, Gazzano, Giacomo, Fugazzola, Laura

“…Cytology is the gold standard method for the differential diagnosis of thyroid nodules, though 25–30% of them are classified as indeterminate. We aimed to set…”
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Extra-nuclear TERT counteracts oxidative stress and promotes progression in papillary thyroid carcinoma by Muzza, Marina, Pogliaghi, Gabriele, Colombo, Carla, Grassi, Elisa Stellaria, Carbone, Erika, Palazzo, Sonia, Frattini, Francesco, Gazzano, Giacomo, Persani, Luca, Fugazzola, Laura

“…The reactivation of TERT is associated with poor outcome in papillary thyroid cancer (PTC). Extra-telomeric functions of TERT were reported, with a protective…”
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Oxidative Stress Correlates with More Aggressive Features in Thyroid Cancer by Muzza, Marina, Pogliaghi, Gabriele, Colombo, Carla, Carbone, Erika, Cirello, Valentina, Palazzo, Sonia, Frattini, Francesco, Gentilini, Davide, Gazzano, Giacomo, Persani, Luca, Fugazzola, Laura

“…Oxidative stress (OS) can have an impact in the pathogenesis and in the progression of thyroid cancer. We investigated the levels of reactive oxygen species…”
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Combined Mutational and Clonality Analyses Support the Existence of Intra-Tumor Heterogeneity in Papillary Thyroid Cancer by Muzza, Marina, Pogliaghi, Gabriele, Persani, Luca, Fugazzola, Laura, Colombo, Carla

“…Despite its potential clinical impact, intra-tumor genetic heterogeneity (ITH) has been scantly investigated in papillary thyroid cancer (PTC). We studied ITH…”
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Genetic variants of PARP4 gene and PARP4P2 pseudogene in patients with multiple primary tumors including thyroid cancer by Cirello, Valentina, Colombo, Carla, Pogliaghi, Gabriele, Proverbio, Maria Carla, Rossi, Stefania, Mussani, Elena, Tosi, Delfina, Bulfamante, Gaetano, Bonoldi, Emanuela, Gherardi, Giorgio, Persani, Luca, Fugazzola, Laura

“…Recently, the PARP4 gene has been identified as a possible susceptibility gene of primary thyroid and breast cancers. We analyzed PARP4 in 53 patients with…”
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Thyroid cancer harboring PTEN and TP53 mutations: A peculiar molecular and clinical case report by Colombo, Carla, Pogliaghi, Gabriele, Tosi, Delfina, Muzza, Marina, Bulfamante, Gaetano, Persani, Luca, Fugazzola, Laura, Cirello, Valentina

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