Search Results - "Poea, Sandrine"
-
1
membrane domain of vacuolar H+ATPase: a crucial player in neurotransmitter exocytotic release
Published in Cellular and molecular life sciences : CMLS (01-07-2015)“…V-ATPases are multimeric enzymes made of two sectors, a V1 catalytic domain and a V0 membrane domain. They accumulate protons in various intracellular…”
Get full text
Journal Article -
2
The molecular basis of p21-activated kinase-associated neurodevelopmental disorders: From genotype to phenotype
Published in Frontiers in neuroscience (02-03-2023)“…Although the identification of numerous genes involved in neurodevelopmental disorders (NDDs) has reshaped our understanding of their etiology, there are still…”
Get full text
Journal Article -
3
Alternative Splicing Controls Neuronal Expression of v-ATPase Subunit a1 and Sorting to Nerve Terminals
Published in The Journal of biological chemistry (23-06-2006)“…Vacuolar proton ATPase accumulates protons inside various intracellular organelles such as synaptic vesicles; its membrane domain V0 could also be involved in…”
Get full text
Journal Article -
4
The V-ATPase membrane domain is a sensor of granular pH that controls the exocytotic machinery
Published in The Journal of cell biology (28-10-2013)“…Several studies have suggested that the V0 domain of the vacuolar-type H(+)-adenosine triphosphatase (V-ATPase) is directly implicated in secretory vesicle…”
Get full text
Journal Article -
5
Antagonistic actions of PAK1 and NF2/Merlin drive myelin membrane expansion in oligodendrocytes
Published in Glia (01-08-2024)“…In the central nervous system, the formation of myelin by oligodendrocytes (OLs) relies on the switch from the polymerization of the actin cytoskeleton to its…”
Get full text
Journal Article -
6
The enhanced cyan fluorescent protein: a sensitive pH sensor for fluorescence lifetime imaging
Published in Analytical and bioanalytical chemistry (01-05-2013)“…pH is an important parameter that affects many functions of live cells, from protein structure or function to several crucial steps of their metabolism…”
Get full text
Journal Article -
7
The renal v-ATPase a4 subunit is expressed in specific subtypes of human gliomas
Published in Glia (01-05-2012)“…Vacuolar H+‐ATPases (v‐ATPases) are multimeric proton pumps which acidify various intra‐cellular organelles and may participate in pHe and pHi regulation in…”
Get full text
Journal Article -
8
PAK3 is a key signature gene of the glioma proneural subtype and affects its proliferation, differentiation and growth
Published in Cellular oncology (Dordrecht) (01-12-2021)“…Purpose Gliomas are the most lethal adult primary brain cancers. Recent advances in their molecular characterization have contributed to a better understanding…”
Get full text
Journal Article -
9
Effects of Cytokines on Acetylcholine Receptor Expression: Implications for Myasthenia Gravis
Published in The Journal of immunology (1950) (15-05-2005)“…Myasthenia gravis is an autoimmune disease associated with thymic pathologies, including hyperplasia. In this study, we investigated the processes that may…”
Get full text
Journal Article -
10
PAK3 mutations responsible for severe intellectual disability and callosal agenesis inhibit cell migration
Published in Neurobiology of disease (01-03-2020)“…Corpus callosum agenesis (CCA) is a brain malformation associated with a wide clinical spectrum including intellectual disability (ID) and an etiopathological…”
Get full text
Journal Article -
11
Establishment of a Human Thymic Myoid Cell Line
Published in The American journal of pathology (01-10-1999)“…The subset of myoid cells is a normal component of the thymic stroma. To characterize these cells, we immortalized stromal cells from human thymus by using a…”
Get full text
Journal Article -
12
Spastic paraplegia 5: Locus refinement, candidate gene analysis and clinical description
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (05-10-2007)“…Thirty‐three different loci for hereditary spastic paraplegias (HSP) have been mapped, and 15 responsible genes have been identified. Autosomal recessive…”
Get full text
Journal Article -
13
NIPA1 (SPG6) mutations are a rare cause of autosomal dominant spastic paraplegia in Europe
Published in Neurogenetics (01-04-2007)Get full text
Journal Article -
14
A Specific Interferon (IFN)-stimulated Response Element of the Distal HLA-G Promoter Binds IFN-regulatory Factor 1 and Mediates Enhancement of This Nonclassical Class I Gene by IFN-β
Published in The Journal of biological chemistry (02-03-2001)“…Type I interferons display a broad range of immunomodulatory functions. Interferon β increases gene expression at the transcriptional level through binding of…”
Get full text
Journal Article -
15
Regulation of acetylcholine receptor gene expression in human myasthenia gravis muscles. Evidences for a compensatory mechanism triggered by receptor loss
Published in The Journal of clinical investigation (01-07-1998)“…Myasthenia gravis (MG) is a neuromuscular disorder mediated by antibodies directed against the acetylcholine receptor (nAChR) resulting in a functional nAChR…”
Get full text
Journal Article -
16
Establishment of a Human Thymic Myoid Cell Line : Phenotypic and Functional Characteristics
Published in The American journal of pathology (01-10-1999)“…The subset of myoid cells is a normal component of the thymic stroma. To characterize these cells, we immortalized stromal cells from human thymus by using a…”
Get full text
Journal Article -
17
Establishment of a human thymic myoid cell line: Phenptypic and functional characteristics
Published in The American journal of pathology (01-10-1999)“…The subset of myoid cells is a normal component of the thymic stroma. To characterize these cells, we immortalized stromal cells from human thymus by using a…”
Get full text
Journal Article -
18
A Specific Interferon (IFN)-stimulated Response Element of the Distal HLA-G Promoter Binds IFN-regulatory Factor 1 and Mediates Enhancement of This Nonclassical Class I Gene by IFN-Î
Published in The Journal of biological chemistry (02-03-2001)“…Type I interferons display a broad range of immunomodulatory functions. Interferon β increases gene expression at the transcriptional level through binding of…”
Get full text
Journal Article -
19
Modulation of acetylcholine receptor expression in seronegative myasthenia gravis
Published in Annals of neurology (01-11-2000)“…In a previous study, we demonstrated a compensatory mechanism for regulating acetylcholine receptor (AChR) gene expression in muscle biopsies from seropositive…”
Get full text
Journal Article -
20
The membrane domain of vacuolar H^sup +^ATPase: a crucial player in neurotransmitter exocytotic release
Published in Cellular and molecular life sciences : CMLS (01-07-2015)“…V-ATPases are multimeric enzymes made of two sectors, a V1 catalytic domain and a V0 membrane domain. They accumulate protons in various intracellular…”
Get full text
Journal Article