Search Results - "Podtelejnikov, A V"

Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid by Huttner, Wieland B, Söling, Hans-Dieter, Schmidt, Anne, Wolde, Michael, Thiele, Christoph, Fest, Werner, Kratzin, Hartmut, Podtelejnikov, Alexandre V, Witke, Walter

“…Endophilin I is a presynaptic protein of unknown function that binds to dynamin, a GTPase that is implicated in endocytosis and recycling of synaptic vesicles…”
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Identification of the Components of Simple Protein Mixtures by High-Accuracy Peptide Mass Mapping and Database Searching by Jensen, Ole N, Podtelejnikov, Alexandre V, Mann, Matthias

“…Peptide mass mapping by matrix-assisted laser desorption/ionization (MALDI) followed by database searching with the set of measured peptide masses is now a…”
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A strategy for identifying gel-separated proteins in sequence databases by MS alone by Shevchenko, A, Wilm, M, Vorm, O, Jensen, O N, Podtelejnikov, A V, Neubauer, G, Shevchenko, A, Mortensen, P, Mann, M

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The nuclear export receptor Xpo1p forms distinct complexes with NES transport substrates and the yeast Ran binding protein 1 (Yrb1p) by Maurer, P, Redd, M, Solsbacher, J, Bischoff, F R, Greiner, M, Podtelejnikov, A V, Mann, M, Stade, K, Weis, K, Schlenstedt, G

“…Xpo1p (Crm1p) is the nuclear export receptor for proteins containing a leucine-rich nuclear export signal (NES). Xpo1p, the NES-containing protein, and…”
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Analysis of Receptor Signaling Pathways by Mass Spectrometry: Identification of Vav-2 as a Substrate of the Epidermal and Platelet-Derived Growth Factor Receptors by Pandey, Akhilesh, Podtelejnikov, Alexandre V., Blagoev, Blagoy, Bustelo, Xosé R., Mann, Matthias, Lodish, Harvey F.

“…Oligomerization of receptor protein tyrosine kinases such as the epidermal growth factor receptor (EGFR) by their cognate ligands leads to activation of the…”
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Linking Genome and Proteome by Mass Spectrometry: Large-Scale Identification of Yeast Proteins from Two Dimensional Gels by Shevchenko, Andrej, Jensen, Ole N., Podtelejnikov, Alexandre V., Sagliocco, Francis, Wilm, Matthias, Vorm, Ole, Mortensen, Peter, Shevchenko, Anna, Boucherie, Helian, Mann, Matthias

“…The function of many of the uncharacterized open reading frames discovered by genomic sequencing can be determined at the level of expressed gene products, the…”
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A Proteomic Approach for Identification of Secreted Proteins during the Differentiation of 3T3-L1 Preadipocytes to Adipocytes by Kratchmarova, Irina, Kalume, Dario E, Blagoev, Blagoy, Scherer, Philipp E, Podtelejnikov, Alexandre V, Molina, Henrik, Bickel, Perry E, Andersen, Jens S, Fernandez, Minerva M, Bunkenborg, Jacob, Roepstorff, Peter, Kristiansen, Karsten, Lodish, Harvey F, Mann, Matthias, Pandey, Akhilesh

“…We have undertaken a systematic proteomic approach to purify and identify secreted factors that are differentially expressed in preadipocytes versus…”
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In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly by Witke, Walter, Podtelejnikov, Alexander V., Nardo, Alessia Di, Sutherland, James D., Gurniak, Christine B., Dotti, Carlos, Mann, Matthias

“…Profilins are thought to be essential for regulation of actin assembly. However, the functions of profilins in mammalian tissues are not well understood. In…”
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The RING-H2 Finger Protein APC11 and the E2 Enzyme UBC4 Are Sufficient to Ubiquitinate Substrates of the Anaphase-Promoting Complex by Gmachl, Michael, Gieffers, Christian, Podtelejnikov, Alexandre V., Mann, Matthias, Peters, Jan-Michael

“…The anaphase-promoting complex (APC) is a cell cycle-regulated ubiquitin-protein ligase that targets cyclin B, securin and other destruction box containing…”
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The complex containing actin-related proteins Arp2 and Arp3 is required for the motility and integrity of yeast actin patches by Winter, Dirk, Podtelejnikov, Alexandre V., Mann, Matthias, Li, Rong

“…Background: Structural modeling and biochemical experiments in vitro have implicated a multi-protein complex containing two actin-related proteins, Arp2 and…”
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Ssdp Proteins Interact with the LIM-Domain-Binding Protein Ldb1 to Regulate Development by Chen, Lan, Segal, Daniel, Hukriede, Neil A., Podtelejnikov, Alexandre V., Bayarsaihan, Dashzeveg, Kennison, James A., Ogryzko, Vasily V., Dawid, Igor B., Westphal, Heiner

“…The LIM-domain-binding protein Ldb1 is a key factor in the assembly of transcriptional complexes involving LIM-homeodomain proteins and other transcription…”
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Use of Mass Spectrometric Methods for Protein Identification in Receptor Research by Schrotz-King, P., Wilm, M., Andersen, J. S., Ashman, K., Podtelejnikov, A. V., Bachi, A., King, A., Mann, M.

“…Abstract In recent years, mass spectrometry has become the method of choice for identifying small amounts of gel separated proteins. Using high mass accuracy…”
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Cloning of a novel phosphotyrosine binding domain containing molecule, Odin, involved in signaling by receptor tyrosine kinases by PANDEY, Akhilesh, BLAGOEV, Blagoy, MANN, Matthias, KRATCHMAROVA, Irina, FERNANDEZ, Minerva, NIELSEN, Mogens, KRISTIANSEN, Troels Zakarias, OHARA, Osamu, PODTELEJNIKOV, Alexandre V, ROCHE, Serge, LODISH, Harvey F

“…We have used a proteomic approach using mass spectrometry to identify signaling molecules involved in receptor tyrosine kinase signaling pathways. Using…”
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Association of yeast RNA polymerase I with a nucleolar substructure active in rRNA synthesis and processing by Fath, S, Milkereit, P, Podtelejnikov, A.V, Bischler, N, Schultz, P, Bier, M, Mann, M, Tschochner, H

“…A novel ribonucleoprotein complex enriched in nucleolar proteins was purified from yeast extracts and constituents were identified by mass spectrometry. When…”
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Correlation of acidic and basic carrier ampholyte and immobilized pH gradient two-dimensional gel electrophoresis patterns based on mass spectrometric protein identification by Nawrocki, A, Larsen, M R, Podtelejnikov, A V, Jensen, O N, Mann, M, Roepstorff, P, Görg, A, Fey, S J, Larsen, P M

“…Separation of proteins on either carrier ampholyte-based or immobilized pH gradient-based two-dimensional (2-D) gels gives rise to electrophoretic patterns…”
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Mitotic regulation of the APC activator proteins CDC20 and CDH1 by Kramer, E R, Scheuringer, N, Podtelejnikov, A V, Mann, M, Peters, J M

“…The ordered activation of the ubiquitin protein ligase anaphase-promoting complex (APC) or cyclosome by CDC20 in metaphase and by CDH1 in telophase is…”
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Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck by Kirschner, Marc W, Eden, Sharon, Rohatgi, Rajat, Podtelejnikov, Alexandre V, Mann, Matthias

“…Rac signalling to actin-a pathway that is thought to be mediated by the protein Scar/WAVE (WASP (Wiskott-Aldrich syndrome protein)-family verprolin homologous…”
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Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability by Mailand, Niels, Podtelejnikov, Alexandre V, Groth, Anja, Mann, Matthias, Bartek, Jiri, Lukas, Jiri

“…DNA replication in higher eukaryotes requires activation of a Cdk2 kinase by Cdc25A, a labile phosphatase subject to further destabilization upon genotoxic…”
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Proteomic Mapping of Brain Plasma Membrane Proteins by Nielsen, Peter Aa, Olsen, Jesper V, Podtelejnikov, Alexandre V, Andersen, Jens R, Mann, Matthias, Wisniewski, Jacek R

“…Proteomics is potentially a powerful technology for elucidating brain function and neurodegenerative diseases. So far, the brain proteome has generally been…”
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Yeast poly(A)-binding protein Pab1 shuttles between the nucleus and the cytoplasm and functions in mRNA export by Brune, Christiane, Munchel, Sarah E, Fischer, Nicole, Podtelejnikov, Alexandre V, Weis, Karsten

“…Pab1 is the major poly(A)-binding protein in yeast. It is a multifunctional protein that mediates many cellular functions associated with the 3'-poly(A)-tail…”
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