Search Results - "Podrez, E. A."

Formation of Nitric Oxide–Derived Oxidants by Myeloperoxidase in Monocytes: Pathways for Monocyte-Mediated Protein Nitration and Lipid Peroxidation In Vivo by Hazen, Stanley L, Zhang, Renliang, Shen, Zhongzhou, Wu, Weijia, Podrez, Eugene A, MacPherson, Jennifer C, Schmitt, David, Mitra, Shome N, Mukhopadhyay, Chaitali, Chen, Yonghong, Cohen, Peter A, Hoff, Henry F, Abu-Soud, Husam M

“…Protein nitration and lipid peroxidation are implicated in the pathogenesis of atherosclerosis; however, neither the cellular mediators nor the reaction…”
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Platelet hyperreactivity, scavenger receptors and atherothrombosis by VALIYAVEETTIL, M., PODREZ, E. A.

“…Scavenger receptors (SRs) were initially identified as macrophage receptors that recognize modified lipoproteins. The lists of SRs, their ligands and cells…”
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Scavenger Receptors Class A-I/II and CD36 Are the Principal Receptors Responsible for the Uptake of Modified Low Density Lipoprotein Leading to Lipid Loading in Macrophages by Kunjathoor, Vidya V., Febbraio, Maria, Podrez, Eugene A., Moore, Kathryn J., Andersson, Lorna, Koehn, Stephanie, Rhee, Jeongmi S., Silverstein, Roy, Hoff, Henry F., Freeman, Mason W.

“…Modification of low density lipoprotein (LDL) can result in the avid uptake of these lipoproteins via a family of macrophage transmembrane proteins referred to…”
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Myeloperoxidase-generated oxidants and atherosclerosis by Podrez, Eugene A., Abu-Soud, Husam M., Hazen, Stanley L.

“…Atherosclerosis is a chronic inflammatory process where oxidative damage within the artery wall is implicated in the pathogenesis of the disease. Mononuclear…”
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Novel aspects of Kindlin‐3 function in humans based on a new case of leukocyte adhesion deficiency III by MELLER, J., MALININ, N. L., PANIGRAHI, S., KERR, B. A., PATIL, A., MA, Y., VENKATESWARAN, L., ROGOZIN, I. B., MOHANDAS, N., EHLAYEL, M. S., PODREZ, E. A., CHINEN, J., BYZOVA, T. V.

“…Background:  Kindlin‐3 is a novel integrin activator in hematopoietic cells, and its deficiency leads to immune problems and severe bleeding, known as…”
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Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice by Febbraio, M, Podrez, E A, Smith, J D, Hajjar, D P, Hazen, S L, Hoff, H F, Sharma, K, Silverstein, R L

“…Macrophage scavenger receptors have been implicated as key players in the pathogenesis of atherosclerosis. To assess the role of the class B scavenger receptor…”
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Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro by Podrez, E A, Schmitt, D, Hoff, H F, Hazen, S L

“…Oxidized LDL is implicated in atherosclerosis; however, the pathways that convert LDL into an atherogenic form in vivo are not established. Production of…”
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Identification of a Novel Family of Oxidized Phospholipids That Serve as Ligands for the Macrophage Scavenger Receptor CD36 by Podrez, Eugene A., Poliakov, Eugenia, Shen, Zhongzhou, Zhang, Renliang, Deng, Yijun, Sun, Mingjiang, Finton, Paula J., Shan, Lian, Gugiu, Bogdan, Fox, Paul L., Hoff, Henry F., Salomon, Robert G., Hazen, Stanley L.

“…The macrophage scavenger receptor CD36 plays an important role in the uptake of oxidized forms of low density lipoprotein (LDL) and contributes to lesion…”
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A Novel Family of Atherogenic Oxidized Phospholipids Promotes Macrophage Foam Cell Formation via the Scavenger Receptor CD36 and Is Enriched in Atherosclerotic Lesions by Podrez, Eugene A., Poliakov, Eugenia, Shen, Zhongzhou, Zhang, Renliang, Deng, Yijun, Sun, Mingjiang, Finton, Paula J., Shan, Lian, Febbraio, Maria, Hajjar, David P., Silverstein, Roy L., Hoff, Henry F., Salomon, Robert G., Hazen, Stanley L.

“…The macrophage scavenger receptor CD36 plays an important role in binding and uptake of oxidized forms of low-density lipoprotein (LDL), foam cell formation,…”
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Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species by Podrez, E A, Febbraio, M, Sheibani, N, Schmitt, D, Silverstein, R L, Hajjar, D P, Cohen, P A, Frazier, W A, Hoff, H F, Hazen, S L

“…The oxidative conversion of LDL into an atherogenic form is considered a pivotal event in the development of cardiovascular disease. Recent studies have…”
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Thrombospondin-1 up-regulates expression of cell adhesion molecules and promotes monocyte binding to endothelium by Narizhneva, Natalya V, Razorenova, Olga V, Podrez, Eugene A, Chen, Juhua, Chandrasekharan, Unni M, DiCorleto, Paul E, Plow, Edward F, Topol, Eric J, Byzova, Tatiana V

“…ABSTRACTExpression of cell adhesion molecules (CAM) responsible for leukocyte‐endothelium interactions plays a crucial role in inflammation and atherogenesis…”
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Measurement of oxidation in plasma Lp(a) in CAPD patients using a novel ELISA by Podrez, Eugene A., O'Neil, June, Salomon, Robert G., Schreiber, Martin J., Hoff, Henry F.

“…Measurement of oxidation in plasma Lp(a) in CAPD patients using a novel ELISA. LGE2 is produced by the cyclooxygenase- or free radical-mediated modification of…”
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Isolevuglandin–protein adducts in humans: products of free radical-induced lipid oxidation through the isoprostane pathway by Salomon, Robert G., Batyreva, Eugenia, Kaur, Kamaljit, Sprecher, Dennis L., Schreiber, Martin J., Crabb, John W., Penn, Marc S., DiCorleto, Angela M., Hazen, Stanley L., Podrez, Eugene A.

“…A family of extremely reactive electrophiles, isolevuglandins (isoLGs), is generated in vivo by free radical-induced lipid oxidation and rearrangement of…”
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Inhibition of cholesterol synthesis by lovastatin tested on six human cell types in vitro by SVIRIDOV, D. D, SAFONOVA, I. G, PAVLOV, M. Y, KOSYKH, V. A, PODREZ, E. A, ANTONOV, A. S, FUKI, I. V, REPIN, V. S

“…Lovastatin (mevinolin) caused a strong and dose-dependent inhibition of cholesterol synthesis in six types of cultured human cells. Fifty percent inhibition of…”
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Effect of chylomicron remnants on cholesterol metabolism in cultured rabbit hepatocytes: Very low density lipoprotein and bile acid production by Kosykh, Vladimir A., Novikov, Dmitri K., Trakht, Iliya N., Podrez, Eugeni A., Victorov, Alexander V., Repin, Vadim S., Smirnov, Viadimir N.

“…The interrelationship between very low density lipoprotein (VLDL) secretion and bile acid production was studied in primary culture of rabbit hepatocytes…”
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Apolipoprotein B release from activated human platelets by Preobrazhensky, S N, Podrez, E A, Tsibulsky, V P, Fuki, I V, Mazurov, A V, Repin, V S, Smirnov, V N

“…Apolipoprotein B (apoB) release from activated washed human platelets was measured by enzyme-linked immunosorbent assay (ELISA) using monospecific rabbit…”
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Very low density lipoprotein secretion by cultured hepatocytes of rabbits fed purified or autoxidized cholesterol by Kosykh, Vladimir A., Lankin, Vadim Z., Podrez, Eugeniy A., Novikov, Dmitriy K., Volgushev, Sergey A., Victorov, Alexander V., Repin, Vaddim S., Smirnov, Vladimir N.

“…The main objectives of this study were to compare the effects of dietary commercial cholesterol (containing 5% of oxidized cholesterol derivatives) and…”
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Effect of bezafibrate on lipoprotein secretion by cultured human hepatocytes by Kosykh, V A, Podrez, E A, Novikov, D K, Victorov, A V, Dolbin, A G, Repin, V S, Smirnov, V N

“…The secretion of newly synthesized very low density lipoprotein and low density lipoprotein (VLDL + LDL) and high density lipoprotein (HDL) in cultured human…”
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Macrophage receptors responsible for distinct recognition of low density lipoprotein containing pyrrole or pyridinium adducts: models of oxidized low density lipoprotein by Podrez, E A, Hoppe, G, O'Neil, J, Sayre, L M, Sheibani, N, Hoff, H F

“…Oxidation of low density lipoproteins (LDL) induced by incubation with Cu(2+) ions results in the formation of a heterogeneous group of aldehydic adducts on…”
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Phorbol ester stimulates platelet spreading and thrombi-like aggregate formation on the surface of immobilized type V collagen by Leytin, V L, Misselwitz, F, Avdonin, P V, Podrez, F A, Domogatsky, S P, Tkachuk, V A

“…We have studied the effect of the tumor-promoting phorbol ester, 4 beta-phorbol-12 beta-myristate-13 a-acetate (PMA), and of the stable prostaglandin…”
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