Search Results - "Podhorez, David E"

Development of a Scalable Process for the Insecticidal Candidate Tyclopyrazoflor. Part 2. Fit-for-Purpose Optimization of the Route to Tyclopyrazoflor Featuring [3 + 2] Cyclization of 3‑Hydrazinopyridine·2HCl and Methyl Acrylate by Yang, Qiang, Li, Xiaoyong, Lorsbach, Beth A, Muhuhi, Joseck M, Roth, Gary A, Gray, Kaitlyn, Podhorez, David E

“…Optimization of the route to the sap-feeding insecticidal candidate tyclopyrazoflor featuring [3 + 2] cyclization of 3-hydrazinopyridine·2HCl and methyl…”
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Development of a Scalable Process for the Insecticidal Candidate Tyclopyrazoflor. Part 1. Evaluation of [3 + 2] Cyclization Strategies to 3‑(3-Chloro‑1H‑pyrazol-1-yl)pyridine by Yang, Qiang, Li, Xiaoyong, Lorsbach, Beth A, Roth, Gary, Podhorez, David E, Ross, Ronald, Niyaz, Noormohamed, Buysse, Ann, Knueppel, Daniel, Nissen, Jeffrey

“…The evaluation of [3 + 2] cyclization strategies to prepare a key intermediate, 3-(3-chloro-1H-pyrazol-1-yl)­pyridine, for the insecticidal candidate…”
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Development of a Scalable Process for the Crop Protection Agent Isoclast by Arndt, Kim E, Bland, Douglas C, Irvine, Nicholas M, Powers, Stacey L, Martin, Timothy P, McConnell, James Russell, Podhorez, David E, Renga, James M, Ross, Ronald, Roth, Gary A, Scherzer, Brian D, Toyzan, Todd W

“…A scalable process to the insecticide Isoclast manufactured by Dow AgroSciences LLC is described. The process involves the de novo construction of a fully…”
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Development of potential manufacturing routes for substituted thiophenes--preparation of halogenated 2-thiophenecarboxylic acid derivatives as building blocks for a new family of 2,6-dihaloaryl 1,2,4-triazole insecticides by Hull, Jr, John W, Romer, Duane R, Podhorez, David E, Ash, Mezzie L, Brady, Christine H

“…Dow AgroSciences has been investigating a new family of functionalized 2,6-dihaloaryl 1,2,4-triazole insecticides featuring specifically targeted insecticidal…”
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Development of Manufacturing Processes for a New Family of 2,6-Dihaloaryl 1,2,4-Triazole Insecticides by Hull, John W, Romer, Duane R, Adaway, Timothy J, Podhorez, David E

“…Details are presented on the process development work for the new 2,6-dihaloaryl-1,2,4-triazole insecticide 1, and the development of a one-pot process toward…”
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Studies in biomimetic alkaloid syntheses. 12. Enantioselective total syntheses of (-)- and (+)-vincadifformine and of (-)-tabersonine by Kuehne, Martin E, Podhorez, David E

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Enantioselective Birch reduction and reductive alkylations of chiral 2-phenylbenzoic acid derivatives. Application to the synthesis of hydrofluoren-9-ones, hydrophenanthren-9-ones, and (-)-(1R,2R)-2-phenylcyclohexanamine by Schultz, Arthur G, Macielag, Mark, Podhorez, David E, Suhadolnik, Joseph C, Kullnig, Rudolph K

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Biomimetic alkaloid syntheses. 15. Enantioselective syntheses with epichlorohydrin: total syntheses of (+)-, (-)- and (.+-.)-vindoline and a synthesis of (-)-vindorosine by Kuehne, Martin E, Podhorez, David E, Mulamba, Tshilundu, Bornmann, William G

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Stepwise approach to the 2,3-dihydroimidazo[1,2-a]pyridine and 5-oxo-1,2,3,5-tetrahydroimidazo[1,2-a]pyridine ring systems by Podhorez, David E.

“…The syntheses of 2,3‐dihydro‐8‐fluoro‐6‐trifluoromethylimidazo[1,2‐a]pyridine‐3‐carbonitrile (2),…”
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