Search Results - "Podgorski, I."
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ICTV Virus Taxonomy Profile: Adenoviridae 2022
Published in Journal of general virology (01-03-2022)“…The family includes non-enveloped viruses with linear dsDNA genomes of 25-48 kb and medium-sized icosahedral capsids. Adenoviruses have been discovered in…”
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Polysialic acid is a cellular receptor for human adenovirus 52
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-2018)“…Human adenovirus 52 (HAdV-52) is one of only three known HAdVs equipped with both a long and a short fiber protein.While the long fiber binds to the coxsackie…”
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Omentum and bone marrow: how adipocyte-rich organs create tumour microenvironments conducive for metastatic progression
Published in Obesity reviews (01-11-2016)“…Summary A number of clinical studies have linked adiposity with increased cancer incidence, progression and metastasis, and adipose tissue is now being…”
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Gene Expression Profiling Reveals Fundamental Sex-Specific Differences in SIRT3-Mediated Redox and Metabolic Signaling in Mouse Embryonic Fibroblasts
Published in International journal of molecular sciences (01-04-2024)“…Sirt-3 is an important regulator of mitochondrial function and cellular energy homeostasis, whose function is associated with aging and various pathologies…”
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Ancient Origins of Cytoskeletal Crosstalk: Spectraplakin-like Proteins Precede the Emergence of Cortical Microtubule Stabilization Complexes as Crosslinkers
Published in International journal of molecular sciences (17-05-2022)“…Adhesion between cells and the extracellular matrix (ECM) is one of the prerequisites for multicellularity, motility, and tissue specialization. Focal…”
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Chronic High Fat Diet Intake Impairs Hepatic Metabolic Parameters in Ovariectomized Sirt3 KO Mice
Published in International journal of molecular sciences (20-04-2021)“…High fat diet (HFD) is an important factor in the development of metabolic diseases, with liver as metabolic center being highly exposed to its influence…”
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Macrophage cathepsin K promotes prostate tumor progression in bone
Published in Oncogene (21-03-2013)“…Bone marrow macrophages (BMMs) share common progenitors with osteoclasts and are critical components of bone–tumor microenvironment; however, their function in…”
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Para -N-Methylpyridinium Pyrenes: Impact of Positive Charge on ds-DNA/RNA and Protein Recognition, Photo-Induced Bioactivity, and Intracellular Localisation
Published in Pharmaceutics (17-11-2022)“…The 2- and 2,7- substituted -N-methylpyridinium pyrene cations show high-affinity intercalation into ds-DNAs, whereas their non-methylated analogues interacted…”
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Role of Sirt3 in Differential Sex-Related Responses to a High-Fat Diet in Mice
Published in Antioxidants (20-02-2020)“…Metabolic homeostasis is differently regulated in males and females. Little is known about the mitochondrial Sirtuin 3 (Sirt3) protein in the context of…”
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Sirt3 Exerts Its Tumor-Suppressive Role by Increasing p53 and Attenuating Response to Estrogen in MCF-7 Cells
Published in Antioxidants (01-04-2020)“…Estrogen (E2) is a major risk factor for the initiation and progression of malignancy in estrogen receptor (ER) positive breast cancers, whereas sirtuin 3…”
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Cathepsin B and tumor proteolysis: contribution of the tumor microenvironment
Published in Seminars in cancer biology (01-04-2005)“…Tumor–stromal interactions induce expression of matrix metalloproteinases and serine proteases and, as shown recently, the cysteine protease cathepsin B. We…”
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Cathepsin K in the bone microenvironment: link between obesity and prostate cancer?
Published in Biochemical Society transactions (01-08-2007)“…The skeleton is the most common site of metastasis in patients with advanced prostate cancer. Despite many advances in targeting skeletal metastases, the…”
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Characterization of monkey adenoviruses with three fiber genes
Published in Infection, genetics and evolution (01-03-2023)“…Although the occurrence of three fiber genes in monkey adenoviruses had already been described, the relatedness of the “extra” fibers have not yet been…”
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Circumventing antivector immunity: potential use of nonhuman adenoviral vectors
Published in Human gene therapy (01-04-2014)“…Adenoviruses are efficient gene delivery vectors based on their ability to transduce a wide variety of cell types and drive high-level transient transgene…”
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Sirtuin 3 drives sex-specific responses to age-related changes in mouse embryonic fibroblasts
Published in Mechanisms of ageing and development (01-12-2024)“…The aging process is a complex phenomenon characterised by a gradual decline in physiological functions and an increased susceptibility to age-related…”
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Genome analysis of four Old World monkey adenoviruses supports the proposed species classification of primate adenoviruses and reveals signs of possible homologous recombination
Published in Journal of general virology (01-07-2016)“…Within the family Adenoviridae, presently Simian mastadenovirus A is the single species approved officially for monkey adenoviruses (AdVs), whilst the…”
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Combination of sirtuin 3 and hyperoxia diminishes tumorigenic properties of MDA-MB-231 cells
Published in Life sciences (1973) (01-08-2020)“…Since the role of the major mitochondrial NAD+-dependent deacetylase, sirtuin 3 (Sirt3), is differential in cancer, opposite to the well-known…”
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Full genome sequence analysis of a novel adenovirus from a captive polar bear (Ursus maritimus)
Published in Virus research (01-02-2020)“…•Novel mastadenovirus found in captive polar bear in Budapest Zoo.•Full sequence was determined using primer walking method.•All genus-common genes present…”
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Taxonomy proposal for Old World monkey adenoviruses: characterisation of several non-human, non-ape primate adenovirus lineages
Published in Archives of virology (01-12-2015)“…A species classification regarding Old World monkey adenoviruses is proposed. We determined the nucleotide sequences of PCR-amplified fragments from the genes…”
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Adenoviruses of the most ancient primate lineages support the theory on virus-host co-evolution
Published in Acta veterinaria Hungarica (Budapest. 1983) (01-09-2018)“…The scarcity or complete lack of information on the adenoviruses (AdVs) occurring in the most ancient non-human primates resulted in the initiation of a study…”
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